ZNF217
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| zinc finger protein 217 | MIM:602967 | Ensembl:ENSG00000171940 | HGNC:HGNC:13009 | PA37588 | 20q13.2 |
Gene Categories:
CLINICALLY ACTIONABLEGO terms in ZNF217
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0000122 | negative regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IDA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IBA | GO:0045892 | negative regulation of transcription, DNA-templated |
| BP | IDA | GO:0045892 | negative regulation of transcription, DNA-templated |
| CC | IDA | GO:0000118 | histone deacetylase complex |
| CC | IDA | GO:0005654 | nucleoplasm |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IDA | GO:0016607 | nuclear speck |
| MF | IDA | GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | ISA | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding |
| MF | IBA | GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | IDA | GO:0001078 | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | TAS | GO:0003700 | DNA-binding transcription factor activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0044212 | transcription regulatory region DNA binding |
| MF | IEA | GO:0046872 | metal ion binding |
Gene expression in normal tissue: ZNF217
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in ZNF217
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-162582 | Signal Transduction |
| reactome | R-HSA-8939211 | ESR-mediated signaling |
| reactome | R-HSA-9006931 | Signaling by Nuclear Receptors |
| reactome | R-HSA-9018519 | Estrogen-dependent gene expression |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD399 | Selumetinib | 3 |
| iGMDRD562 | Navitoclax | 5 |
| iGMDRD780 | PP-30 | 4 |
| iGMDRD577 | BIX01294 | 2 |
| iGMDRD888 | Compound 44 | 2 |
| iGMDRD506 | Fedratinib | 5 |
| iGMDRD64 | Parbendazole | 1 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD524 | ISX-9 | 5 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD513 | BML-259 | 2 |
| iGMDRD260 | FQI-2 | 3 |
| iGMDRD171 | Pemetrexed | 2 |
| iGMDRD782 | DC-45-A2 | 2 |
| iGMDRD870 | BRD63610 | 1 |
| iGMDRD441 | TW 37 | 1 |
| iGMDRD885 | Compound 110 | 4 |
| iGMDRD318 | PAC-1 | 2 |
| iGMDRD226 | ML006 | 4 |
| iGMDRD201 | SKI II | 2 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD61 | Kinetin riboside | 3 |
| iGMDRD193 | Fqi1 | 1 |
| iGMDRD639 | YK 4-279 | 2 |
| iGMDRD394 | BX-795 | 3 |
| iGMDRD280 | CYTOCHALASIN B | 2 |
| iGMDRD375 | GW-405833 | 2 |
| iGMDRD151 | CHM-1 | 3 |
| iGMDRD76 | Simvastatin | 2 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD144 | NSC95397 | 4 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD781 | Sirolimus | 8 |
| iGMDRD483 | SCH-529074 | 2 |
| iGMDRD552 | AZD-1775 | 5 |
| iGMDRD263 | AACOCF3 | 4 |
| iGMDRD505 | Pevonedistat | 6 |
| iGMDRD82 | Quiflapon | 3 |
| iGMDRD202 | Curcumin | 5 |
| iGMDRD251 | ML162 | 2 |
| iGMDRD5 | Tyrphostin AG 1478 | 5 |
| iGMDRD705 | Nakiterpiosin | 3 |
| iGMDRD289 | Parthenolide | 4 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD231 | Importazole | 2 |
| iGMDRD481 | Dactolisib | 2 |
| iGMDRD237 | ABT-751 | 1 |
| iGMDRD57 | Chloropentafluorobenzene | 2 |
| iGMDRD698 | Neratinib | 5 |
| iGMDRD945 | ML214 | 2 |
| iGMDRD486 | Tosedostat | 4 |
| iGMDRD560 | MK-2206 | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ZNF217
CLASSFICATION
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