iGMDRD513
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| BML-259 | CHEMBL426972 | 16760000 | Alone | Small Molecule |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 2 |
| 27102 | EIF2AK1 | 1 |
| 6664 | SOX11 | 3 |
| 79054 | TRPM8 | 4 |
| 7128 | TNFAIP3 | 4 |
| 6491 | STIL | 1 |
| 8444 | DYRK3 | 2 |
| 21 | ABCA3 | 1 |
| 132 | ADK | 2 |
| 8476 | CDC42BPA | 3 |
| 840 | CASP7 | 3 |
| 1969 | EPHA2 | 2 |
| 23097 | CDK19 | 1 |
| 80070 | ADAMTS20 | 1 |
| 26511 | CHIC2 | 1 |
| 3431 | SP110 | 1 |
| 6938 | TCF12 | 1 |
| 7764 | ZNF217 | 2 |
| 10863 | ADAM28 | 1 |
| 1607 | DGKB | 2 |
| 3320 | HSP90AA1 | 3 |
| 3066 | HDAC2 | 2 |
| 7253 | TSHR | 1 |
| 54822 | TRPM7 | 4 |
| 80122 | MAP3K19 | 1 |
| 202374 | STK32A | 1 |
| 1387 | CREBBP | 2 |
| 23225 | NUP210 | 3 |
| 5579 | PRKCB | 2 |
| 7133 | TNFRSF1B | 1 |
| 51755 | CDK12 | 1 |
| 3604 | TNFRSF9 | 2 |
| 5899 | RALB | 1 |
| 5159 | PDGFRB | 3 |
| 7373 | COL14A1 | 1 |
| 7173 | TPO | 2 |
| 5465 | PPARA | 3 |
| 9578 | CDC42BPB | 2 |
| 23522 | KAT6B | 2 |
| 5900 | RALGDS | 3 |
| 256646 | NUTM1 | 1 |
| 22806 | IKZF3 | 1 |
| 10342 | TFG | 1 |
| 7416 | VDAC1 | 3 |
| 4005 | LMO2 | 3 |
| 22984 | PDCD11 | 2 |
| 5468 | PPARG | 1 |
| 6733 | SRPK2 | 2 |
| 80129 | CCDC170 | 1 |
| 10188 | TNK2 | 2 |
| 2736 | GLI2 | 1 |
| 83990 | BRIP1 | 2 |
| 51804 | SIX4 | 2 |
| 6928 | HNF1B | 1 |
| 140901 | STK35 | 3 |
| 2064 | ERBB2 | 3 |
| 983 | CDK1 | 3 |
| 57476 | GRAMD1B | 3 |
| 79971 | WLS | 1 |
| 7486 | WRN | 2 |
| 5573 | PRKAR1A | 3 |
| 4140 | MARK3 | 1 |
| 5286 | PIK3C2A | 2 |
| 25989 | ULK3 | 3 |
| 8859 | STK19 | 1 |
| 3667 | IRS1 | 3 |
| 51433 | ANAPC5 | 1 |
| 6792 | CDKL5 | 2 |
| 1123 | CHN1 | 2 |
| 5450 | POU2AF1 | 3 |
| 91461 | PKDCC | 1 |
| 23152 | CIC | 3 |
| 904 | CCNT1 | 1 |
| 10413 | YAP1 | 1 |
| 1029 | CDKN2A | 2 |
| 23048 | FNBP1 | 1 |
| 5336 | PLCG2 | 1 |
| 4855 | NOTCH4 | 1 |
| 356 | FASLG | 3 |
| 3000 | GUCY2D | 1 |
| 7249 | TSC2 | 1 |
| 65243 | ZFP69B | 2 |
| 4869 | NPM1 | 2 |
| 8874 | ARHGEF7 | 4 |
| 51086 | TNNI3K | 4 |
| 4921 | DDR2 | 1 |
| 2177 | FANCD2 | 4 |
| 55589 | BMP2K | 1 |
| 136332 | LRGUK | 3 |
| 5650 | KLK7 | 2 |
| 6280 | S100A9 | 3 |
| 4089 | SMAD4 | 2 |
| 6654 | SOS1 | 3 |
| 23373 | CRTC1 | 1 |
| 285220 | EPHA6 | 2 |
| 51366 | UBR5 | 3 |
| 5297 | PI4KA | 1 |
| 8216 | LZTR1 | 1 |
| 3702 | ITK | 4 |
| 9972 | NUP153 | 1 |
| 3239 | HOXD13 | 3 |
| 7043 | TGFB3 | 1 |
| 5789 | PTPRD | 3 |
| 26278 | SACS | 2 |
| 51265 | CDKL3 | 2 |
| 5156 | PDGFRA | 1 |
| 5187 | PER1 | 3 |
| 375056 | MIA3 | 3 |
| 1544 | CYP1A2 | 1 |
| 673 | BRAF | 4 |
| 84630 | TTBK1 | 4 |
| 4790 | NFKB1 | 1 |
| 3315 | HSPB1 | 3 |
| 23532 | PRAME | 3 |
| 4863 | NPAT | 3 |
| 83452 | RAB33B | 1 |
| 8924 | HERC2 | 2 |
| 2078 | ERG | 1 |
| 867 | CBL | 1 |
| 6095 | RORA | 3 |
| 7468 | NSD2 | 1 |
| 8626 | TP63 | 6 |
| 5294 | PIK3CG | 2 |
| 7849 | PAX8 | 3 |
| 8621 | CDK13 | 3 |
| 1316 | KLF6 | 3 |
| 1869 | E2F1 | 2 |
| 1974 | EIF4A2 | 2 |
| 660 | BMX | 3 |
| 6146 | RPL22 | 2 |
| 8301 | PICALM | 3 |
| 1018 | CDK3 | 1 |
| 5582 | PRKCG | 4 |
| 7465 | WEE1 | 3 |
| 6789 | STK4 | 1 |
| 7454 | WAS | 6 |
| 7036 | TFR2 | 1 |
| 8028 | MLLT10 | 1 |
| 29959 | NRBP1 | 2 |
| 2046 | EPHA8 | 2 |
| 10249 | GLYAT | 2 |
| 5532 | PPP3CB | 1 |
| 2072 | ERCC4 | 1 |
| 332 | BIRC5 | 1 |
| 64764 | CREB3L2 | 3 |
| 8031 | NCOA4 | 1 |
| 55289 | ACOXL | 1 |
| 7094 | TLN1 | 3 |
| 54101 | RIPK4 | 3 |
| 2776 | GNAQ | 1 |
| 7099 | TLR4 | 3 |
| 65267 | WNK3 | 1 |
| 2719 | GPC3 | 3 |
| 5932 | RBBP8 | 2 |
| 2122 | MECOM | 2 |
| 3662 | IRF4 | 1 |
| 1209 | CLPTM1 | 2 |
| 7403 | KDM6A | 3 |
| 2258 | FGF13 | 3 |
| 4302 | MLLT6 | 3 |
| 5586 | PKN2 | 1 |
| 9878 | TOX4 | 3 |
| 51135 | IRAK4 | 1 |
| 2651 | GCNT2 | 2 |
| 11086 | ADAM29 | 2 |
| 581 | BAX | 1 |
| 8321 | FZD1 | 1 |
| 4763 | NF1 | 2 |
| 65975 | STK33 | 3 |
| 440270 | GOLGA8B | 2 |
| 57096 | RPGRIP1 | 1 |
| 4629 | MYH11 | 1 |
| 23683 | PRKD3 | 1 |
| 3679 | ITGA7 | 1 |
| 10048 | RANBP9 | 3 |
| 699 | BUB1 | 4 |
| 83732 | RIOK1 | 1 |
| 3895 | KTN1 | 1 |
| 2892 | GRIA3 | 4 |
| 1436 | CSF1R | 1 |
| 2904 | GRIN2B | 2 |
| 5590 | PRKCZ | 2 |
Gene in drug-gene network: Network Plot
Models in BML-259
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.