CDC42BPB
Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:614062 Ensembl IDEnsembl:ENSG00000198752 HGNC IDHGNC:HGNC:1738 PHARMGKB IDPA26268 Map Location14q32.32 | |||||
GO terms in CDC42BPB
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IDA | GO:0006468 | protein phosphorylation |
| BP | ISS | GO:0006468 | protein phosphorylation |
| BP | TAS | GO:0007010 | cytoskeleton organization |
| BP | TAS | GO:0007163 | establishment or maintenance of cell polarity |
| BP | TAS | GO:0007165 | signal transduction |
| BP | IMP | GO:0016477 | cell migration |
Gene expression in normal tissue: CDC42BPB
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CDC42BPB
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CDC42BPB
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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