iGMDRD524
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| ISX-9 | CHEMBL1222381 | 19582700 | Alone | Small Molecule |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 5 |
| 3696 | ITGB8 | 6 |
| 64901 | RANBP17 | 5 |
| 1147 | CHUK | 1 |
| 7128 | TNFAIP3 | 3 |
| 132 | ADK | 6 |
| 8476 | CDC42BPA | 3 |
| 4627 | MYH9 | 2 |
| 4168 | MCF2 | 5 |
| 2200 | FBN1 | 3 |
| 150465 | TTL | 6 |
| 1520 | CTSS | 3 |
| 57554 | LRRC7 | 3 |
| 7272 | TTK | 6 |
| 347365 | ITIH6 | 5 |
| 2100 | ESR2 | 3 |
| 80070 | ADAMTS20 | 1 |
| 84700 | MYO18B | 1 |
| 5593 | PRKG2 | 3 |
| 79092 | CARD14 | 5 |
| 53616 | ADAM22 | 5 |
| 1263 | PLK3 | 3 |
| 7764 | ZNF217 | 5 |
| 353345 | GPR141 | 4 |
| 5133 | PDCD1 | 4 |
| 3069 | HDLBP | 3 |
| 9530 | BAG4 | 2 |
| 4771 | NF2 | 6 |
| 1786 | DNMT1 | 1 |
| 10863 | ADAM28 | 2 |
| 3694 | ITGB6 | 2 |
| 10142 | AKAP9 | 3 |
| 7253 | TSHR | 4 |
| 2241 | FER | 2 |
| 57172 | CAMK1G | 3 |
| 9816 | URB2 | 3 |
| 51199 | NIN | 1 |
| 112858 | TP53RK | 2 |
| 1387 | CREBBP | 6 |
| 3604 | TNFRSF9 | 2 |
| 8295 | TRRAP | 5 |
| 5159 | PDGFRB | 6 |
| 7173 | TPO | 2 |
| 4851 | NOTCH1 | 3 |
| 5314 | PKHD1 | 2 |
| 51512 | GTSE1 | 6 |
| 89910 | UBE3B | 6 |
| 974 | CD79B | 6 |
| 9578 | CDC42BPB | 3 |
| 23522 | KAT6B | 3 |
| 440279 | UNC13C | 3 |
| 8767 | RIPK2 | 6 |
| 57787 | MARK4 | 1 |
| 5613 | PRKX | 2 |
| 329 | BIRC2 | 3 |
| 64083 | GOLPH3 | 5 |
| 7416 | VDAC1 | 3 |
| 8313 | AXIN2 | 3 |
| 1050 | CEBPA | 3 |
| 2260 | FGFR1 | 6 |
| 10188 | TNK2 | 5 |
| 9636 | ISG15 | 3 |
| 11169 | WDHD1 | 3 |
| 2736 | GLI2 | 3 |
| 83990 | BRIP1 | 3 |
| 51804 | SIX4 | 1 |
| 284217 | LAMA1 | 2 |
| 269 | AMHR2 | 3 |
| 7424 | VEGFC | 6 |
| 238 | ALK | 2 |
| 399979 | SNX19 | 3 |
| 22858 | ICK | 6 |
| 287015 | TRIM42 | 5 |
| 83983 | TSSK6 | 3 |
| 8643 | PTCH2 | 2 |
| 8395 | PIP5K1B | 3 |
| 6663 | SOX10 | 3 |
| 1456 | CSNK1G3 | 5 |
| 783 | CACNB2 | 2 |
| 5580 | PRKCD | 3 |
| 6416 | MAP2K4 | 7 |
| 92 | ACVR2A | 2 |
| 1452 | CSNK1A1 | 6 |
| 57510 | XPO5 | 3 |
| 25989 | ULK3 | 3 |
| 6709 | SPTAN1 | 3 |
| 8215 | DVL1P1 | 3 |
| 50488 | MINK1 | 4 |
| 79705 | LRRK1 | 3 |
| 4046 | LSP1 | 3 |
| 6464 | SHC1 | 2 |
| 6098 | ROS1 | 2 |
| 8515 | ITGA10 | 2 |
| 3685 | ITGAV | 2 |
| 80243 | PREX2 | 6 |
| 8945 | BTRC | 1 |
| 139285 | AMER1 | 6 |
| 3418 | IDH2 | 3 |
| 28996 | HIPK2 | 1 |
| 3397 | ID1 | 5 |
| 9096 | TBX18 | 3 |
| 4058 | LTK | 2 |
| 1496 | CTNNA2 | 3 |
| 23152 | CIC | 3 |
| 2050 | EPHB4 | 1 |
| 2272 | FHIT | 1 |
| 7867 | MAPKAPK3 | 6 |
| 5327 | PLAT | 2 |
| 7184 | HSP90B1 | 2 |
| 139728 | PNCK | 3 |
| 5129 | CDK18 | 3 |
| 157753 | TMEM74 | 3 |
| 57523 | NYNRIN | 2 |
| 2868 | GRK4 | 3 |
| 9874 | TLK1 | 3 |
| 58508 | KMT2C | 3 |
| 7157 | TP53 | 3 |
| 2099 | ESR1 | 5 |
| 4602 | MYB | 2 |
| 4855 | NOTCH4 | 3 |
| 6794 | STK11 | 3 |
| 8218 | CLTCL1 | 3 |
| 3791 | KDR | 3 |
| 114788 | CSMD3 | 1 |
| 130399 | ACVR1C | 6 |
| 225689 | MAPK15 | 3 |
| 5585 | PKN1 | 4 |
| 1019 | CDK4 | 1 |
| 65243 | ZFP69B | 3 |
| 1045 | CDX2 | 1 |
| 85481 | PSKH2 | 3 |
| 5604 | MAP2K1 | 3 |
| 863 | CBFA2T3 | 3 |
| 55034 | MOCOS | 3 |
| 57188 | ADAMTSL3 | 3 |
| 57105 | CYSLTR2 | 6 |
| 136332 | LRGUK | 6 |
| 50945 | TBX22 | 3 |
| 676 | BRDT | 3 |
| 5650 | KLK7 | 2 |
| 5871 | MAP4K2 | 2 |
| 2081 | ERN1 | 4 |
| 8997 | KALRN | 3 |
| 2175 | FANCA | 2 |
| 4089 | SMAD4 | 4 |
| 51284 | TLR7 | 3 |
| 8288 | EPX | 3 |
| 6654 | SOS1 | 1 |
| 2668 | GDNF | 6 |
| 10948 | STARD3 | 1 |
| 1848 | DUSP6 | 3 |
| 4139 | MARK1 | 6 |
| 285220 | EPHA6 | 2 |
| 546 | ATRX | 3 |
| 10769 | PLK2 | 3 |
| 64840 | PORCN | 2 |
| 340533 | NEXMIF | 3 |
| 1198 | CLK3 | 2 |
| 5290 | PIK3CA | 2 |
| 1514 | CTSL | 2 |
| 2318 | FLNC | 6 |
| 4803 | NGF | 2 |
| 7075 | TIE1 | 4 |
| 640 | BLK | 2 |
| 4609 | MYC | 1 |
| 91 | ACVR1B | 1 |
| 10461 | MERTK | 3 |
| 90427 | BMF | 2 |
| 6885 | MAP3K7 | 1 |
| 894 | CCND2 | 6 |
| 833 | CARS | 3 |
| 7917 | BAG6 | 1 |
| 375056 | MIA3 | 2 |
| 91754 | NEK9 | 3 |
| 3949 | LDLR | 2 |
| 203102 | ADAM32 | 3 |
| 1213 | CLTC | 3 |
| 84879 | MFSD2A | 3 |
| 23532 | PRAME | 2 |
| 4863 | NPAT | 1 |
| 57538 | ALPK3 | 5 |
| 8924 | HERC2 | 2 |
| 120892 | LRRK2 | 6 |
| 65268 | WNK2 | 3 |
| 6095 | RORA | 6 |
| 4298 | MLLT1 | 2 |
| 5979 | RET | 3 |
| 9321 | TRIP11 | 2 |
| 9451 | EIF2AK3 | 2 |
| 654780 | LOC654780 | 6 |
| 8491 | MAP4K3 | 3 |
| 8621 | CDK13 | 2 |
| 5563 | PRKAA2 | 3 |
| 23049 | SMG1 | 4 |
| 55521 | TRIM36 | 2 |
| 5728 | PTEN | 1 |
| 5595 | MAPK3 | 5 |
| 23281 | MTUS2 | 3 |
| 284086 | NEK8 | 1 |
| 3554 | IL1R1 | 3 |
| 83666 | PARP9 | 1 |
| 5305 | PIP4K2A | 2 |
| 2897 | GRIK1 | 3 |
| 85409 | NKD2 | 3 |
| 1950 | EGF | 2 |
| 177 | AGER | 3 |
| 2870 | GRK6 | 1 |
| 23090 | ZNF423 | 4 |
| 4055 | LTBR | 3 |
| 28954 | REM1 | 5 |
| 7273 | TTN | 4 |
| 1445 | CSK | 6 |
| 55356 | SLC22A15 | 3 |
| 85415 | RHPN2 | 3 |
| 203447 | NRK | 3 |
| 2277 | VEGFD | 5 |
| 29959 | NRBP1 | 2 |
| 23411 | SIRT1 | 1 |
| 53904 | MYO3A | 2 |
| 79012 | CAMKV | 2 |
| 9372 | ZFYVE9 | 1 |
| 54861 | SNRK | 3 |
| 128869 | PIGU | 3 |
| 8821 | INPP4B | 2 |
| 51151 | SLC45A2 | 3 |
| 5291 | PIK3CB | 4 |
| 558 | AXL | 2 |
| 9748 | SLK | 1 |
| 5581 | PRKCE | 2 |
| 5923 | RASGRF1 | 3 |
| 4774 | NFIA | 1 |
| 9021 | SOCS3 | 1 |
| 5395 | PMS2 | 1 |
| 860 | RUNX2 | 1 |
| 53353 | LRP1B | 1 |
| 1281 | COL3A1 | 2 |
| 9659 | PDE4DIP | 2 |
| 9201 | DCLK1 | 5 |
| 63976 | PRDM16 | 2 |
| 598 | BCL2L1 | 5 |
| 5170 | PDPK1 | 2 |
| 57007 | ACKR3 | 3 |
| 8317 | CDC7 | 1 |
| 3717 | JAK2 | 3 |
| 57147 | SCYL3 | 1 |
| 11040 | PIM2 | 1 |
| 8428 | STK24 | 3 |
| 2719 | GPC3 | 3 |
| 4261 | CIITA | 3 |
| 84072 | HORMAD1 | 1 |
| 170685 | NUDT10 | 6 |
| 7046 | TGFBR1 | 1 |
| 5087 | PBX1 | 1 |
| 5054 | SERPINE1 | 1 |
| 4217 | MAP3K5 | 3 |
| 63923 | TNN | 6 |
| 2074 | ERCC6 | 3 |
| 8661 | EIF3A | 3 |
| 7403 | KDM6A | 6 |
| 8841 | HDAC3 | 3 |
| 4638 | MYLK | 2 |
| 2261 | FGFR3 | 1 |
| 8711 | TNK1 | 3 |
| 4040 | LRP6 | 1 |
| 84446 | BRSK1 | 2 |
| 4841 | NONO | 1 |
| 3092 | HIP1 | 2 |
| 4593 | MUSK | 3 |
| 4629 | MYH11 | 4 |
| 30811 | HUNK | 3 |
| 1608 | DGKG | 5 |
| 23112 | TNRC6B | 2 |
| 2444 | FRK | 1 |
| 2892 | GRIA3 | 3 |
Gene in drug-gene network: Network Plot
Models in ISX-9
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.