SNX19

Summary: Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016].

Loading, please wait...
Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namesorting nexin 19
OMIM ID
Ensembl IDEnsembl:ENSG00000120451
HGNC IDHGNC:HGNC:21532
PHARMGKB IDPA134904352
Map Location11q24.3-q25

GO terms in SNX19


Loading, please wait...
Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IEA GO:0032266 phosphatidylinositol-3-phosphate binding
CC IDA GO:0005737 cytoplasm
CC IEA GO:0030659 cytoplasmic vesicle membrane
CC IEA GO:0031901 early endosome membrane
BP IMP GO:0002062 chondrocyte differentiation
Showing 1 to 6 of 9 rows

Gene expression in normal tissue: SNX19

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in SNX19


Loading, please wait...
Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


Loading, please wait...
Drug ID
Drug Name
Model Num.
iGMDRD387 CHIR-99021 3
iGMDRD486 Tosedostat 1
iGMDRD483 SCH-529074 6
iGMDRD494 Neopeltolide 3
Showing 1 to 4 of 25 rows rows per page

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in SNX19

Loading, please wait...
Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

​​​​

SITE
DATATYPES
CLASSFICATION
Map

Copyright © 2018 Modellab | All Rights Reserved

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.