iGMDRD116
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| CD437 | CHEMBL1180 | 135411 | Alone | Small Molecule |
Drug Targets:
RARGDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 2 |
| 1105 | CHD1 | 3 |
| 4854 | NOTCH3 | 2 |
| 7514 | XPO1 | 1 |
| 5296 | PIK3R2 | 2 |
| 5027 | P2RX7 | 2 |
| 7837 | PXDN | 3 |
| 79054 | TRPM8 | 3 |
| 23085 | ERC1 | 2 |
| 7128 | TNFAIP3 | 3 |
| 6491 | STIL | 6 |
| 10987 | COPS5 | 3 |
| 6774 | STAT3 | 2 |
| 4926 | NUMA1 | 4 |
| 2986 | GUCY2F | 4 |
| 2956 | MSH6 | 1 |
| 1520 | CTSS | 3 |
| 57554 | LRRC7 | 3 |
| 3845 | KRAS | 2 |
| 8289 | ARID1A | 2 |
| 6351 | CCL4 | 1 |
| 80070 | ADAMTS20 | 2 |
| 701 | BUB1B | 2 |
| 8573 | CASK | 2 |
| 4036 | LRP2 | 3 |
| 10395 | DLC1 | 1 |
| 3069 | HDLBP | 5 |
| 10892 | MALT1 | 3 |
| 1786 | DNMT1 | 2 |
| 3066 | HDAC2 | 2 |
| 22821 | RASA3 | 5 |
| 79934 | COQ8B | 3 |
| 10454 | TAB1 | 3 |
| 3727 | JUND | 3 |
| 2313 | FLI1 | 3 |
| 31 | ACACA | 5 |
| 9048 | ARTN | 3 |
| 5596 | MAPK4 | 1 |
| 9411 | ARHGAP29 | 2 |
| 8295 | TRRAP | 3 |
| 10438 | C1D | 2 |
| 9024 | BRSK2 | 3 |
| 7373 | COL14A1 | 3 |
| 5166 | PDK4 | 3 |
| 89910 | UBE3B | 3 |
| 55294 | FBXW7 | 2 |
| 2033 | EP300 | 7 |
| 6927 | HNF1A | 1 |
| 641 | BLM | 1 |
| 4361 | MRE11 | 3 |
| 64324 | NSD1 | 3 |
| 83439 | TCF7L1 | 3 |
| 25865 | PRKD2 | 3 |
| 10818 | FRS2 | 5 |
| 54477 | PLEKHA5 | 3 |
| 440279 | UNC13C | 2 |
| 27065 | NSG1 | 1 |
| 4301 | AFDN | 4 |
| 84033 | OBSCN | 2 |
| 342667 | STAC2 | 3 |
| 8600 | TNFSF11 | 3 |
| 3621 | ING1 | 3 |
| 57787 | MARK4 | 2 |
| 1586 | CYP17A1 | 3 |
| 7416 | VDAC1 | 3 |
| 6041 | RNASEL | 3 |
| 5468 | PPARG | 3 |
| 200576 | PIKFYVE | 3 |
| 8313 | AXIN2 | 2 |
| 2042 | EPHA3 | 5 |
| 2260 | FGFR1 | 3 |
| 114548 | NLRP3 | 3 |
| 10298 | PAK4 | 1 |
| 1936 | EEF1D | 2 |
| 269 | AMHR2 | 1 |
| 4982 | TNFRSF11B | 2 |
| 2045 | EPHA7 | 1 |
| 399979 | SNX19 | 3 |
| 171019 | ADAMTS19 | 3 |
| 375449 | MAST4 | 2 |
| 4752 | NEK3 | 3 |
| 65217 | PCDH15 | 3 |
| 440730 | TRIM67 | 3 |
| 5127 | CDK16 | 3 |
| 2068 | ERCC2 | 3 |
| 5568 | PRKACG | 6 |
| 9472 | AKAP6 | 2 |
| 2778 | GNAS | 3 |
| 472 | ATM | 1 |
| 2580 | GAK | 2 |
| 1009 | CDH11 | 3 |
| 53942 | CNTN5 | 1 |
| 1123 | CHN1 | 3 |
| 7010 | TEK | 4 |
| 7533 | YWHAH | 6 |
| 1029 | CDKN2A | 2 |
| 57523 | NYNRIN | 3 |
| 10018 | BCL2L11 | 7 |
| 7157 | TP53 | 2 |
| 6092 | ROBO2 | 1 |
| 4088 | SMAD3 | 3 |
| 6794 | STK11 | 1 |
| 2322 | FLT3 | 2 |
| 57194 | ATP10A | 1 |
| 25836 | NIPBL | 2 |
| 960 | CD44 | 1 |
| 4292 | MLH1 | 3 |
| 93210 | PGAP3 | 3 |
| 4086 | SMAD1 | 1 |
| 1019 | CDK4 | 1 |
| 11213 | IRAK3 | 3 |
| 84075 | FSCB | 5 |
| 344387 | CDKL4 | 3 |
| 9088 | PKMYT1 | 3 |
| 55437 | STRADB | 2 |
| 4921 | DDR2 | 6 |
| 65125 | WNK1 | 1 |
| 136332 | LRGUK | 8 |
| 8997 | KALRN | 2 |
| 2071 | ERCC3 | 3 |
| 23469 | PHF3 | 3 |
| 6654 | SOS1 | 4 |
| 7204 | TRIO | 3 |
| 285220 | EPHA6 | 2 |
| 23678 | SGK3 | 2 |
| 30827 | CXXC1 | 3 |
| 56997 | COQ8A | 5 |
| 4214 | MAP3K1 | 6 |
| 3702 | ITK | 2 |
| 9972 | NUP153 | 4 |
| 3239 | HOXD13 | 3 |
| 50615 | IL21R | 2 |
| 5290 | PIK3CA | 2 |
| 3720 | JARID2 | 5 |
| 5034 | P4HB | 3 |
| 10565 | ARFGEF1 | 6 |
| 57154 | SMURF1 | 3 |
| 2030 | SLC29A1 | 3 |
| 1956 | EGFR | 3 |
| 2735 | GLI1 | 3 |
| 4609 | MYC | 10 |
| 8795 | TNFRSF10B | 2 |
| 4684 | NCAM1 | 1 |
| 1031 | CDKN2C | 1 |
| 6446 | SGK1 | 3 |
| 3553 | IL1B | 2 |
| 1594 | CYP27B1 | 2 |
| 5747 | PTK2 | 2 |
| 3635 | INPP5D | 2 |
| 7917 | BAG6 | 3 |
| 27330 | RPS6KA6 | 3 |
| 203102 | ADAM32 | 4 |
| 84630 | TTBK1 | 2 |
| 1769 | DNAH8 | 2 |
| 4863 | NPAT | 1 |
| 780 | DDR1 | 3 |
| 83452 | RAB33B | 1 |
| 8924 | HERC2 | 3 |
| 6502 | SKP2 | 2 |
| 120892 | LRRK2 | 5 |
| 84441 | MAML2 | 5 |
| 5205 | ATP8B1 | 2 |
| 5979 | RET | 3 |
| 10253 | SPRY2 | 5 |
| 4853 | NOTCH2 | 2 |
| 1230 | CCR1 | 5 |
| 9509 | ADAMTS2 | 1 |
| 8312 | AXIN1 | 2 |
| 10752 | CHL1 | 5 |
| 51330 | TNFRSF12A | 6 |
| 667 | DST | 6 |
| 284086 | NEK8 | 1 |
| 2188 | FANCF | 3 |
| 2648 | KAT2A | 1 |
| 85409 | NKD2 | 2 |
| 7273 | TTN | 2 |
| 5582 | PRKCG | 3 |
| 23332 | CLASP1 | 3 |
| 85415 | RHPN2 | 2 |
| 23389 | MED13L | 1 |
| 2277 | VEGFD | 1 |
| 8667 | EIF3H | 4 |
| 387 | RHOA | 3 |
| 29941 | PKN3 | 3 |
| 2046 | EPHA8 | 1 |
| 7150 | TOP1 | 3 |
| 10243 | GPHN | 8 |
| 8394 | PIP5K1A | 4 |
| 344905 | ATP13A5 | 3 |
| 51151 | SLC45A2 | 2 |
| 7248 | TSC1 | 3 |
| 5923 | RASGRF1 | 6 |
| 2317 | FLNB | 7 |
| 6790 | AURKA | 2 |
| 9223 | MAGI1 | 5 |
| 55289 | ACOXL | 2 |
| 1281 | COL3A1 | 1 |
| 9659 | PDE4DIP | 3 |
| 283455 | KSR2 | 3 |
| 131890 | GRK7 | 2 |
| 2194 | FASN | 3 |
| 5927 | KDM5A | 2 |
| 598 | BCL2L1 | 2 |
| 57448 | BIRC6 | 4 |
| 7227 | TRPS1 | 7 |
| 5506 | PPP1R3A | 6 |
| 6778 | STAT6 | 3 |
| 4772 | NFATC1 | 2 |
| 80216 | ALPK1 | 1 |
| 5932 | RBBP8 | 5 |
| 182 | JAG1 | 2 |
| 80781 | COL18A1 | 5 |
| 8536 | CAMK1 | 3 |
| 2122 | MECOM | 5 |
| 3815 | KIT | 2 |
| 6653 | SORL1 | 3 |
| 4974 | OMG | 3 |
| 5925 | RB1 | 2 |
| 2065 | ERBB3 | 1 |
| 7403 | KDM6A | 3 |
| 7508 | XPC | 2 |
| 4638 | MYLK | 1 |
| 197259 | MLKL | 2 |
| 55959 | SULF2 | 6 |
| 4915 | NTRK2 | 3 |
| 11086 | ADAM29 | 3 |
| 142 | PARP1 | 3 |
| 2261 | FGFR3 | 3 |
| 23072 | HECW1 | 1 |
| 5567 | PRKACB | 5 |
| 4763 | NF1 | 3 |
| 9625 | AATK | 2 |
| 63893 | UBE2O | 6 |
| 1840 | DTX1 | 3 |
| 5287 | PIK3C2B | 1 |
| 3679 | ITGA7 | 3 |
| 1803 | DPP4 | 2 |
| 1499 | CTNNB1 | 4 |
| 3440 | IFNA2 | 2 |
| 1795 | DOCK3 | 1 |
| 167359 | NIM1K | 1 |
| 5970 | RELA | 5 |
| 1488 | CTBP2 | 3 |
Gene in drug-gene network: Network Plot
Models in CD437
CLASSFICATION
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