CDK16

Summary: The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It may play a role in signal transduction cascades in terminally differentiated cells; in exocytosis; and in transport of secretory cargo from the endoplasmic reticulum. This gene is thought to escape X inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2009].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namecyclin dependent kinase 16
OMIM IDMIM:311550
Ensembl IDEnsembl:ENSG00000102225
HGNC IDHGNC:HGNC:8749
PHARMGKB IDPA33095
Map LocationXp11.3

GO terms in CDK16


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IBA GO:0005634 nucleus
CC IBA GO:0005737 cytoplasm
CC IDA GO:0005737 cytoplasm
CC IDA GO:0005829 cytosol
CC IDA GO:0005886 plasma membrane
CC IBA GO:0008021 synaptic vesicle
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Gene expression in normal tissue: CDK16

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

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Pathways in CDK16


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Database
Pathway ID
Pathway Des.
No matching records found

Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD772 BRD4770 3
iGMDRD512 nutlin 3 3
iGMDRD255 SB225002 2
iGMDRD434 BMS-536924 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CDK16

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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