SEARCH

HOME / SEARCH / NSC95397

iGMDRD144

Canonical SMILES: C1=CC=C2C(=C1)C(=O)C(=C(C2=O)SCCO)SCCO

InChI: InChI=1S/C14H14O4S2/c15-5-7-19-13-11(17)9-3-1-2-4-10(9)12(18)14(13)20-8-6-16/h1-4,15-16H,5-8H2

InChI Key: MAASHDQFQDDECQ-UHFFFAOYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
NSC95397	CHEMBL429095	262093	Alone	Small Molecule

Drug Targets:

CDC25A CDC25B CDC25C

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
3696	ITGB8	3
7514	XPO1	1
6664	SOX11	1
7074	TIAM1	2
1464	CSPG4	3
10641	NPRL2	4
7128	TNFAIP3	1
6491	STIL	2
10987	COPS5	6
21	ABCA3	3
3383	ICAM1	3
5933	RBL1	3
2986	GUCY2F	3
79947	DHDDS	3
5546	PRCC	3
7171	TPM4	5
220064	LTO1	2
1520	CTSS	3
93	ACVR2B	6
3845	KRAS	3
4750	NEK1	6
23552	CDK20	2
8289	ARID1A	7
80070	ADAMTS20	1
8266	UBL4A	2
701	BUB1B	6
3939	LDHA	3
2335	FN1	3
53616	ADAM22	4
6597	SMARCA4	8
9869	SETDB1	3
8780	RIOK3	2
7764	ZNF217	4
353345	GPR141	3
5133	PDCD1	2
3069	HDLBP	2
11116	FGFR1OP	8
10320	IKZF1	2
3209	HOXA13	2
7942	TFEB	3
390502	SERPINA2	2
56776	FMN2	3
10892	MALT1	3
6598	SMARCB1	3
3694	ITGB6	2
23213	SULF1	3
3320	HSP90AA1	2
3066	HDAC2	3
22853	LMTK2	3
55781	RIOK2	3
7253	TSHR	9
23310	NCAPD3	3
10645	CAMKK2	2
5298	PI4KB	3
8749	ADAM18	4
2241	FER	5
22821	RASA3	4
2249	FGF4	2
79934	COQ8B	5
54822	TRPM7	3
1387	CREBBP	4
1893	ECM1	4
10454	TAB1	3
3727	JUND	3
2885	GRB2	3
5788	PTPRC	2
2313	FLI1	3
56164	STK31	5
10013	HDAC6	3
10178	TENM1	1
79858	NEK11	7
9048	ARTN	6
85021	REPS1	3
8295	TRRAP	5
2977	GUCY1A2	5
11122	PTPRT	2
9024	BRSK2	3
5159	PDGFRB	3
7173	TPO	2
10215	OLIG2	8
5605	MAP2K2	6
139378	ADGRG4	8
7158	TP53BP1	3
145264	SERPINA12	3
2033	EP300	2
8784	TNFRSF18	4
9578	CDC42BPB	2
641	BLM	2
10746	MAP3K2	2
10006	ABI1	2
25925	ZNF521	2
4610	MYCL	8
3976	LIF	3
4301	AFDN	2
816	CAMK2B	3
5081	PAX7	2
5900	RALGDS	6
1880	GPR183	3
122011	CSNK1A1L	2
57787	MARK4	4
4478	MSN	3
1586	CYP17A1	4
1591	CYP24A1	6
5613	PRKX	8
22806	IKZF3	8
166614	DCLK2	2
9175	MAP3K13	5
200576	PIKFYVE	5
80351	TNKS2	2
8313	AXIN2	6
6733	SRPK2	1
5330	PLCB2	3
730249	ACOD1	3
10217	CTDSPL	2
2736	GLI2	5
29904	EEF2K	6
388581	C1QTNF12	3
83931	STK40	2
2045	EPHA7	6
7078	TIMP3	2
171019	ADAMTS19	5
94103	ORMDL3	2
57476	GRAMD1B	2
83983	TSSK6	2
286826	LIN9	6
23387	SIK3	7
4294	MAP3K10	3
1456	CSNK1G3	2
5127	CDK16	2
6416	MAP2K4	3
7525	YES1	5
6709	SPTAN1	3
158056	MAMDC4	5
2068	ERCC2	5
8859	STK19	6
8515	ITGA10	4
6917	TCEA1	4
472	ATM	2
1009	CDH11	4
53942	CNTN5	5
84433	CARD11	5
9564	BCAR1	2
4804	NGFR	3
1123	CHN1	2
1496	CTNNA2	1
5450	POU2AF1	3
898	CCNE1	3
23152	CIC	2
2050	EPHB4	3
2272	FHIT	8
7681	MKRN3	3
1647	GADD45A	3
5327	PLAT	3
5863	RGL2	2
51517	NCKIPSD	3
10413	YAP1	9
2201	FBN2	2
27436	EML4	2
57523	NYNRIN	4
8576	STK16	3
7157	TP53	2
6092	ROBO2	3
4088	SMAD3	3
6714	SRC	1
6794	STK11	5
2322	FLT3	2
57194	ATP10A	7
3791	KDR	3
93210	PGAP3	4
54498	SMOX	3
2263	FGFR2	6
1019	CDK4	3
7409	VAV1	2
65243	ZFP69B	7
9967	THRAP3	4
85481	PSKH2	3
5604	MAP2K1	3
344387	CDKL4	4
863	CBFA2T3	2
55034	MOCOS	3
9088	PKMYT1	3
55437	STRADB	2
3572	IL6ST	5
9965	FGF19	2
57188	ADAMTSL3	2
57591	MRTFA	2
136332	LRGUK	3
4436	MSH2	1
50945	TBX22	3
6035	RNASE1	3
676	BRDT	2
1656	DDX6	3
5650	KLK7	3
5871	MAP4K2	9
23365	ARHGEF12	3
84181	CHD6	2
8997	KALRN	3
7994	KAT6A	1
4089	SMAD4	2
7471	WNT1	2
54658	UGT1A1	1
6654	SOS1	4
1848	DUSP6	3
2737	GLI3	2
5727	PTCH1	3
546	ATRX	3
85414	SLC45A3	3
2047	EPHB1	5
7786	MAP3K12	6
30827	CXXC1	3
56997	COQ8A	6
57144	PAK5	3
286133	SCARA5	3
3702	ITK	8
440275	EIF2AK4	2
3239	HOXD13	9
3720	JARID2	2
5034	P4HB	6
4145	MATK	9
7043	TGFB3	3
10565	ARFGEF1	6
64919	BCL11B	9
4803	NGF	2
10155	TRIM28	3
7075	TIE1	2
1956	EGFR	9
640	BLK	5
157680	VPS13B	9
4609	MYC	1
64750	SMURF2	5
2624	GATA2	2
5789	PTPRD	1
1459	CSNK2A2	4
10461	MERTK	3
8795	TNFRSF10B	2
4684	NCAM1	3
26278	SACS	9
5462	POU5F1B	2
1440	CSF3	5
79759	ZNF668	2
204851	HIPK1	3
3635	INPP5D	2
1653	DDX1	6
7917	BAG6	2
93627	TBCK	10
27330	RPS6KA6	2
7189	TRAF6	1
6872	TAF1	2
203102	ADAM32	2
84630	TTBK1	5
1981	EIF4G1	3
4790	NFKB1	3
84879	MFSD2A	9
1769	DNAH8	2
3315	HSPB1	3
23532	PRAME	4
83452	RAB33B	2
8924	HERC2	2
89795	NAV3	2
65268	WNK2	2
7027	TFDP1	3
6095	RORA	5
7301	TYRO3	1
8029	CUBN	2
7849	PAX8	3
5979	RET	2
10253	SPRY2	6
9451	EIF2AK3	6
2017	CTTN	3
7286	TUFT1	2
9843	HEPH	3
266747	RGL4	1
5563	PRKAA2	5
23742	NPAP1	8
23049	SMG1	3
10752	CHL1	3
57521	RPTOR	3
208	AKT2	3
51330	TNFRSF12A	3
7155	TOP2B	4
1869	E2F1	3
80124	VCPIP1	3
667	DST	2
1613	DAPK3	2
2897	GRIK1	3
6146	RPL22	2
1950	EGF	2
6009	RHEB	3
8301	PICALM	6
23090	ZNF423	2
28954	REM1	1
91807	MYLK3	3
79834	PEAK1	3
5582	PRKCG	2
56616	DIABLO	3
2119	ETV5	3
55356	SLC22A15	3
8667	EIF3H	6
54904	NSD3	4
53904	MYO3A	2
8648	NCOA1	3
29941	PKN3	5
9372	ZFYVE9	3
2046	EPHA8	2
286151	FBXO43	3
344905	ATP13A5	3
5588	PRKCQ	3
51151	SLC45A2	1
10076	PTPRU	3
2690	GHR	1
2317	FLNB	6
9021	SOCS3	3
100124696	TEC	3
9223	MAGI1	2
860	RUNX2	2
53353	LRP1B	5
55289	ACOXL	2
9659	PDE4DIP	3
7293	TNFRSF4	10
6093	ROCK1	2
131890	GRK7	2
5927	KDM5A	3
598	BCL2L1	2
3579	CXCR2	3
5589	PRKCSH	3
57448	BIRC6	4
2304	FOXE1	5
23139	MAST2	3
79837	PIP4K2C	2
3709	ITPR2	3
57147	SCYL3	3
27004	TCL6	2
8428	STK24	22
3552	IL1A	1
8569	MKNK1	3
11076	TPPP	2
5894	RAF1	1
7046	TGFBR1	8
2122	MECOM	2
51167	CYB5R4	6
3815	KIT	2
9212	AURKB	3
4974	OMG	5
2074	ERCC6	1
7403	KDM6A	3
51364	ZMYND10	3
255239	ANKK1	3
7040	TGFB1	9
30849	PIK3R4	2
3480	IGF1R	3
2011	MARK2	4
2261	FGFR3	3
8711	TNK1	6
84446	BRSK1	3
55422	ZNF331	4
54518	APBB1IP	3
595	CCND1	2
1612	DAPK1	2
5260	PHKG1	1
4613	MYCN	5
63893	UBE2O	5
494551	WEE2	6
1840	DTX1	2
10891	PPARGC1A	4
440270	GOLGA8B	4
57096	RPGRIP1	5
2044	EPHA5	2
4629	MYH11	3
3679	ITGA7	3
6943	TCF21	9
1608	DGKG	6
3440	IFNA2	4
1436	CSF1R	3
4916	NTRK3	9
167359	NIM1K	1
4486	MST1R	6
5970	RELA	2

Gene in drug-gene network: Network Plot

Models in NSC95397

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.