SCARA5
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| scavenger receptor class A member 5 | MIM:611306 | Ensembl:ENSG00000168079 | HGNC:HGNC:28701 | PA142670948 | 8p21.1 |
GO terms in SCARA5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0005044 | scavenger receptor activity |
| MF | ISS | GO:0070287 | ferritin receptor activity |
| CC | ISS | GO:0005887 | integral component of plasma membrane |
| CC | IEA | GO:0009986 | cell surface |
| BP | ISS | GO:0006879 | cellular iron ion homeostasis |
| BP | ISS | GO:0006897 | endocytosis |
| BP | IEA | GO:0006898 | receptor-mediated endocytosis |
| BP | IEA | GO:0034605 | cellular response to heat |
| BP | ISS | GO:0034755 | iron ion transmembrane transport |
| BP | ISS | GO:0070207 | protein homotrimerization |
Gene expression in normal tissue: SCARA5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SCARA5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-2173782 | Binding and Uptake of Ligands by Scavenger Receptors |
| reactome | R-HSA-3000480 | Scavenging by Class A Receptors |
| reactome | R-HSA-5653656 | Vesicle-mediated transport |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD781 | Sirolimus | 1 |
| iGMDRD150 | RITA | 6 |
| iGMDRD345 | Compound 10b [PMID: 11504634] | 1 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD329 | Merck60 | 6 |
| iGMDRD577 | BIX01294 | 3 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD100 | Zebularine | 5 |
| iGMDRD356 | PNU-74654 | 3 |
| iGMDRD634 | SCHEMBL2608041 | 3 |
| iGMDRD300 | Tozasertib | 3 |
| iGMDRD123 | Isoevodiamine | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SCARA5
CLASSFICATION
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