iGMDRD398
Standard Name | Pubchem CID | Drug Status | Drug Type |
---|---|---|---|
Sepantronium | 10126200 | Alone | Small Molecule |
Drug Targets:
BIRC5 (Survivin)Drug Pathways:
Apoptosis regulationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene ID | Gene Name | Model Num. |
---|---|---|
64901 | RANBP17 | 3 |
1147 | CHUK | 1 |
9833 | MELK | 1 |
4854 | NOTCH3 | 3 |
7514 | XPO1 | 1 |
7074 | TIAM1 | 2 |
3725 | JUN | 3 |
10903 | MTMR11 | 2 |
7535 | ZAP70 | 1 |
79054 | TRPM8 | 3 |
10221 | TRIB1 | 3 |
3383 | ICAM1 | 3 |
8915 | BCL10 | 2 |
8476 | CDC42BPA | 3 |
7161 | TP73 | 3 |
11183 | MAP4K5 | 2 |
29101 | SSU72 | 3 |
4291 | MLF1 | 3 |
8929 | PHOX2B | 3 |
2200 | FBN1 | 4 |
7171 | TPM4 | 3 |
3708 | ITPR1 | 1 |
1588 | CYP19A1 | 2 |
1520 | CTSS | 3 |
93 | ACVR2B | 3 |
4750 | NEK1 | 3 |
2100 | ESR2 | 2 |
8266 | UBL4A | 2 |
5934 | RBL2 | 3 |
57143 | ADCK1 | 6 |
2335 | FN1 | 3 |
4928 | NUP98 | 6 |
53616 | ADAM22 | 2 |
6938 | TCF12 | 3 |
7850 | IL1R2 | 3 |
9475 | ROCK2 | 3 |
83942 | TSSK1B | 2 |
2176 | FANCC | 3 |
5241 | PGR | 3 |
5133 | PDCD1 | 2 |
29888 | STRN4 | 3 |
5079 | PAX5 | 4 |
64783 | RBM15 | 4 |
10863 | ADAM28 | 2 |
1136 | CHRNA3 | 3 |
23213 | SULF1 | 3 |
22853 | LMTK2 | 6 |
23310 | NCAPD3 | 2 |
6318 | SERPINB4 | 2 |
4092 | SMAD7 | 3 |
84299 | MIEN1 | 2 |
7048 | TGFBR2 | 2 |
112858 | TP53RK | 2 |
1893 | ECM1 | 2 |
5756 | TWF1 | 2 |
2043 | EPHA4 | 2 |
2313 | FLI1 | 3 |
56164 | STK31 | 2 |
2984 | GUCY2C | 4 |
9048 | ARTN | 2 |
5966 | REL | 2 |
9411 | ARHGAP29 | 2 |
5074 | PAWR | 3 |
85021 | REPS1 | 2 |
3604 | TNFRSF9 | 2 |
29998 | BICRA | 2 |
10438 | C1D | 3 |
27148 | STK36 | 1 |
5396 | PRRX1 | 3 |
55351 | STK32B | 5 |
7173 | TPO | 2 |
139378 | ADGRG4 | 2 |
7158 | TP53BP1 | 5 |
89910 | UBE3B | 2 |
4001 | LMNB1 | 3 |
9578 | CDC42BPB | 2 |
23522 | KAT6B | 2 |
55728 | N4BP2 | 3 |
10006 | ABI1 | 3 |
102 | ADAM10 | 2 |
55819 | RNF130 | 3 |
5900 | RALGDS | 3 |
11073 | TOPBP1 | 2 |
7025 | NR2F1 | 3 |
2051 | EPHB6 | 4 |
608 | TNFRSF17 | 3 |
4478 | MSN | 3 |
8549 | LGR5 | 6 |
22806 | IKZF3 | 2 |
166614 | DCLK2 | 2 |
7416 | VDAC1 | 3 |
3645 | INSRR | 2 |
8313 | AXIN2 | 3 |
6733 | SRPK2 | 2 |
6091 | ROBO1 | 2 |
2042 | EPHA3 | 3 |
29904 | EEF2K | 3 |
51804 | SIX4 | 3 |
4194 | MDM4 | 2 |
269 | AMHR2 | 2 |
83931 | STK40 | 2 |
55681 | SCYL2 | 2 |
238 | ALK | 2 |
171019 | ADAMTS19 | 2 |
983 | CDK1 | 1 |
85443 | DCLK3 | 4 |
6850 | SYK | 1 |
54899 | PXK | 2 |
23191 | CYFIP1 | 3 |
5127 | CDK16 | 3 |
9759 | HDAC4 | 1 |
25989 | ULK3 | 3 |
8215 | DVL1P1 | 2 |
10087 | COL4A3BP | 3 |
5591 | PRKDC | 3 |
8859 | STK19 | 2 |
80312 | TET1 | 3 |
659 | BMPR2 | 2 |
9472 | AKAP6 | 1 |
8515 | ITGA10 | 2 |
2778 | GNAS | 2 |
3667 | IRS1 | 2 |
80243 | PREX2 | 3 |
472 | ATM | 2 |
2734 | GLG1 | 3 |
54986 | ULK4 | 2 |
5289 | PIK3C3 | 1 |
898 | CCNE1 | 1 |
23152 | CIC | 2 |
7681 | MKRN3 | 3 |
56648 | EIF5A2 | 3 |
10062 | NR1H3 | 3 |
5108 | PCM1 | 2 |
9794 | MAML1 | 2 |
8576 | STK16 | 3 |
9874 | TLK1 | 1 |
11143 | KAT7 | 3 |
27347 | STK39 | 2 |
7157 | TP53 | 1 |
6794 | STK11 | 1 |
7869 | SEMA3B | 2 |
6184 | RPN1 | 4 |
2133 | EXT3 | 3 |
1045 | CDX2 | 2 |
8833 | GMPS | 3 |
344387 | CDKL4 | 3 |
8874 | ARHGEF7 | 8 |
5597 | MAPK6 | 6 |
10516 | FBLN5 | 2 |
136332 | LRGUK | 2 |
652 | BMP4 | 2 |
1656 | DDX6 | 3 |
5650 | KLK7 | 3 |
8115 | TCL1A | 3 |
6103 | RPGR | 1 |
4437 | MSH3 | 3 |
23269 | MGA | 4 |
7994 | KAT6A | 1 |
57551 | TAOK1 | 5 |
4089 | SMAD4 | 4 |
54658 | UGT1A1 | 1 |
6654 | SOS1 | 8 |
672 | BRCA1 | 2 |
2737 | GLI3 | 2 |
7204 | TRIO | 1 |
256536 | TCERG1L | 3 |
9252 | RPS6KA5 | 2 |
139760 | GPR119 | 3 |
78989 | COLEC11 | 2 |
23373 | CRTC1 | 2 |
5727 | PTCH1 | 2 |
9448 | MAP4K4 | 2 |
285220 | EPHA6 | 2 |
51366 | UBR5 | 6 |
23678 | SGK3 | 5 |
85414 | SLC45A3 | 3 |
2047 | EPHB1 | 2 |
7786 | MAP3K12 | 2 |
57144 | PAK5 | 4 |
286133 | SCARA5 | 3 |
440275 | EIF2AK4 | 2 |
5290 | PIK3CA | 1 |
1514 | CTSL | 4 |
90 | ACVR1 | 3 |
7043 | TGFB3 | 3 |
2318 | FLNC | 2 |
10565 | ARFGEF1 | 2 |
5530 | PPP3CA | 2 |
3458 | IFNG | 2 |
26166 | RGS22 | 3 |
28958 | COA3 | 3 |
1956 | EGFR | 2 |
157680 | VPS13B | 2 |
64333 | ARHGAP9 | 2 |
5599 | MAPK8 | 5 |
1459 | CSNK2A2 | 2 |
8013 | NR4A3 | 6 |
90427 | BMF | 2 |
100130933 | SMIM6 | 3 |
5462 | POU5F1B | 2 |
1440 | CSF3 | 2 |
51265 | CDKL3 | 3 |
51701 | NLK | 3 |
2189 | FANCG | 3 |
7443 | VRK1 | 2 |
1653 | DDX1 | 3 |
8900 | CCNA1 | 2 |
5187 | PER1 | 3 |
7917 | BAG6 | 3 |
375056 | MIA3 | 3 |
91754 | NEK9 | 1 |
3949 | LDLR | 3 |
57082 | KNL1 | 2 |
4790 | NFKB1 | 3 |
1769 | DNAH8 | 2 |
4863 | NPAT | 3 |
780 | DDR1 | 3 |
57538 | ALPK3 | 1 |
2078 | ERG | 3 |
339345 | NANOS2 | 2 |
120892 | LRRK2 | 1 |
65268 | WNK2 | 2 |
867 | CBL | 4 |
1677 | DFFB | 3 |
84441 | MAML2 | 2 |
7301 | TYRO3 | 1 |
8178 | ELL | 1 |
10253 | SPRY2 | 3 |
5378 | PMS1 | 5 |
9451 | EIF2AK3 | 2 |
7286 | TUFT1 | 3 |
4853 | NOTCH2 | 4 |
9509 | ADAMTS2 | 2 |
266747 | RGL4 | 2 |
8312 | AXIN1 | 2 |
208 | AKT2 | 5 |
2796 | GNRH1 | 3 |
80124 | VCPIP1 | 2 |
4914 | NTRK1 | 2 |
667 | DST | 2 |
83666 | PARP9 | 2 |
2897 | GRIK1 | 2 |
6770 | STAR | 3 |
1950 | EGF | 2 |
177 | AGER | 3 |
995 | CDC25C | 3 |
7059 | THBS3 | 3 |
55359 | STYK1 | 3 |
6787 | NEK4 | 2 |
29959 | NRBP1 | 3 |
53904 | MYO3A | 2 |
387 | RHOA | 2 |
55561 | CDC42BPG | 3 |
128869 | PIGU | 2 |
10243 | GPHN | 3 |
221895 | JAZF1 | 2 |
8805 | TRIM24 | 2 |
10595 | ERN2 | 6 |
2072 | ERCC4 | 4 |
5588 | PRKCQ | 2 |
1493 | CTLA4 | 3 |
10076 | PTPRU | 2 |
558 | AXL | 2 |
332 | BIRC5 | 2 |
3297 | HSF1 | 3 |
2690 | GHR | 4 |
2041 | EPHA1 | 2 |
8031 | NCOA4 | 3 |
5395 | PMS2 | 4 |
860 | RUNX2 | 5 |
1789 | DNMT3B | 2 |
140913 | PPIAP10 | 3 |
5609 | MAP2K7 | 2 |
9659 | PDE4DIP | 2 |
9201 | DCLK1 | 2 |
4000 | LMNA | 4 |
54101 | RIPK4 | 2 |
6093 | ROCK1 | 5 |
3624 | INHBA | 5 |
598 | BCL2L1 | 1 |
5587 | PRKD1 | 1 |
900 | CCNG1 | 3 |
2321 | FLT1 | 2 |
6196 | RPS6KA2 | 6 |
5681 | PSKH1 | 6 |
22982 | DIP2C | 4 |
7227 | TRPS1 | 4 |
5506 | PPP1R3A | 4 |
8899 | PRPF4B | 5 |
51562 | MBIP | 3 |
6777 | STAT5B | 2 |
3552 | IL1A | 2 |
80216 | ALPK1 | 1 |
5915 | RARB | 3 |
330 | BIRC3 | 3 |
4330 | MN1 | 3 |
170685 | NUDT10 | 3 |
11076 | TPPP | 2 |
23250 | ATP11A | 3 |
7913 | DEK | 3 |
51167 | CYB5R4 | 3 |
1760 | DMPK | 3 |
2065 | ERBB3 | 1 |
5324 | PLAG1 | 3 |
3691 | ITGB4 | 2 |
1432 | MAPK14 | 6 |
4615 | MYD88 | 3 |
8841 | HDAC3 | 4 |
197259 | MLKL | 7 |
255239 | ANKK1 | 2 |
55959 | SULF2 | 2 |
171017 | ZNF384 | 3 |
2011 | MARK2 | 2 |
23092 | ARHGAP26 | 4 |
9262 | STK17B | 6 |
2261 | FGFR3 | 2 |
139604 | MAGEB16 | 3 |
79577 | CDC73 | 4 |
84197 | POMK | 2 |
1013 | CDH15 | 3 |
581 | BAX | 3 |
3092 | HIP1 | 3 |
57697 | FANCM | 3 |
440270 | GOLGA8B | 5 |
2044 | EPHA5 | 2 |
4593 | MUSK | 2 |
23683 | PRKD3 | 3 |
699 | BUB1 | 2 |
4193 | MDM2 | 2 |
6868 | ADAM17 | 1 |
2444 | FRK | 5 |
27151 | CPAMD8 | 2 |
1436 | CSF1R | 3 |
2886 | GRB7 | 3 |
2904 | GRIN2B | 2 |
5624 | PROC | 5 |
1488 | CTBP2 | 2 |
Gene in drug-gene network: Network Plot
Models in Sepantronium