iGMDRD398


Canonical SMILES: CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4

InChI: InChI=1S/C20H19N4O3/c1-13-23(9-10-27-2)17-18(24(13)12-14-11-21-7-8-22-14)20(26)16-6-4-3-5-15(16)19(17)25/h3-8,11H,9-10,12H2,1-2H3/q+1

InChI Key: OTSOOHRUMBRSHZ-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
Sepantronium10126200AloneSmall Molecule

Drug Targets:

BIRC5 (Survivin)

Drug Pathways:

Apoptosis regulation

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
64901RANBP173
1147CHUK1
9833MELK1
4854NOTCH33
7514XPO11
7074TIAM12
3725JUN3
10903MTMR112
7535ZAP701
79054TRPM83
10221TRIB13
3383ICAM13
8915BCL102
8476CDC42BPA3
7161TP733
11183MAP4K52
29101SSU723
4291MLF13
8929PHOX2B3
2200FBN14
7171TPM43
3708ITPR11
1588CYP19A12
1520CTSS3
93ACVR2B3
4750NEK13
2100ESR22
8266UBL4A2
5934RBL23
57143ADCK16
2335FN13
4928NUP986
53616ADAM222
6938TCF123
7850IL1R23
9475ROCK23
83942TSSK1B2
2176FANCC3
5241PGR3
5133PDCD12
29888STRN43
5079PAX54
64783RBM154
10863ADAM282
1136CHRNA33
23213SULF13
22853LMTK26
23310NCAPD32
6318SERPINB42
4092SMAD73
84299MIEN12
7048TGFBR22
112858TP53RK2
1893ECM12
5756TWF12
2043EPHA42
2313FLI13
56164STK312
2984GUCY2C4
9048ARTN2
5966REL2
9411ARHGAP292
5074PAWR3
85021REPS12
3604TNFRSF92
29998BICRA2
10438C1D3
27148STK361
5396PRRX13
55351STK32B5
7173TPO2
139378ADGRG42
7158TP53BP15
89910UBE3B2
4001LMNB13
9578CDC42BPB2
23522KAT6B2
55728N4BP23
10006ABI13
102ADAM102
55819RNF1303
5900RALGDS3
11073TOPBP12
7025NR2F13
2051EPHB64
608TNFRSF173
4478MSN3
8549LGR56
22806IKZF32
166614DCLK22
7416VDAC13
3645INSRR2
8313AXIN23
6733SRPK22
6091ROBO12
2042EPHA33
29904EEF2K3
51804SIX43
4194MDM42
269AMHR22
83931STK402
55681SCYL22
238ALK2
171019ADAMTS192
983CDK11
85443DCLK34
6850SYK1
54899PXK2
23191CYFIP13
5127CDK163
9759HDAC41
25989ULK33
8215DVL1P12
10087COL4A3BP3
5591PRKDC3
8859STK192
80312TET13
659BMPR22
9472AKAP61
8515ITGA102
2778GNAS2
3667IRS12
80243PREX23
472ATM2
2734GLG13
54986ULK42
5289PIK3C31
898CCNE11
23152CIC2
7681MKRN33
56648EIF5A23
10062NR1H33
5108PCM12
9794MAML12
8576STK163
9874TLK11
11143KAT73
27347STK392
7157TP531
6794STK111
7869SEMA3B2
6184RPN14
2133EXT33
1045CDX22
8833GMPS3
344387CDKL43
8874ARHGEF78
5597MAPK66
10516FBLN52
136332LRGUK2
652BMP42
1656DDX63
5650KLK73
8115TCL1A3
6103RPGR1
4437MSH33
23269MGA4
7994KAT6A1
57551TAOK15
4089SMAD44
54658UGT1A11
6654SOS18
672BRCA12
2737GLI32
7204TRIO1
256536TCERG1L3
9252RPS6KA52
139760GPR1193
78989COLEC112
23373CRTC12
5727PTCH12
9448MAP4K42
285220EPHA62
51366UBR56
23678SGK35
85414SLC45A33
2047EPHB12
7786MAP3K122
57144PAK54
286133SCARA53
440275EIF2AK42
5290PIK3CA1
1514CTSL4
90ACVR13
7043TGFB33
2318FLNC2
10565ARFGEF12
5530PPP3CA2
3458IFNG2
26166RGS223
28958COA33
1956EGFR2
157680VPS13B2
64333ARHGAP92
5599MAPK85
1459CSNK2A22
8013NR4A36
90427BMF2
100130933SMIM63
5462POU5F1B2
1440CSF32
51265CDKL33
51701NLK3
2189FANCG3
7443VRK12
1653DDX13
8900CCNA12
5187PER13
7917BAG63
375056MIA33
91754NEK91
3949LDLR3
57082KNL12
4790NFKB13
1769DNAH82
4863NPAT3
780DDR13
57538ALPK31
2078ERG3
339345NANOS22
120892LRRK21
65268WNK22
867CBL4
1677DFFB3
84441MAML22
7301TYRO31
8178ELL1
10253SPRY23
5378PMS15
9451EIF2AK32
7286TUFT13
4853NOTCH24
9509ADAMTS22
266747RGL42
8312AXIN12
208AKT25
2796GNRH13
80124VCPIP12
4914NTRK12
667DST2
83666PARP92
2897GRIK12
6770STAR3
1950EGF2
177AGER3
995CDC25C3
7059THBS33
55359STYK13
6787NEK42
29959NRBP13
53904MYO3A2
387RHOA2
55561CDC42BPG3
128869PIGU2
10243GPHN3
221895JAZF12
8805TRIM242
10595ERN26
2072ERCC44
5588PRKCQ2
1493CTLA43
10076PTPRU2
558AXL2
332BIRC52
3297HSF13
2690GHR4
2041EPHA12
8031NCOA43
5395PMS24
860RUNX25
1789DNMT3B2
140913PPIAP103
5609MAP2K72
9659PDE4DIP2
9201DCLK12
4000LMNA4
54101RIPK42
6093ROCK15
3624INHBA5
598BCL2L11
5587PRKD11
900CCNG13
2321FLT12
6196RPS6KA26
5681PSKH16
22982DIP2C4
7227TRPS14
5506PPP1R3A4
8899PRPF4B5
51562MBIP3
6777STAT5B2
3552IL1A2
80216ALPK11
5915RARB3
330BIRC33
4330MN13
170685NUDT103
11076TPPP2
23250ATP11A3
7913DEK3
51167CYB5R43
1760DMPK3
2065ERBB31
5324PLAG13
3691ITGB42
1432MAPK146
4615MYD883
8841HDAC34
197259MLKL7
255239ANKK12
55959SULF22
171017ZNF3843
2011MARK22
23092ARHGAP264
9262STK17B6
2261FGFR32
139604MAGEB163
79577CDC734
84197POMK2
1013CDH153
581BAX3
3092HIP13
57697FANCM3
440270GOLGA8B5
2044EPHA52
4593MUSK2
23683PRKD33
699BUB12
4193MDM22
6868ADAM171
2444FRK5
27151CPAMD82
1436CSF1R3
2886GRB73
2904GRIN2B2
5624PROC5
1488CTBP22

Gene in drug-gene network: Network Plot

Models in Sepantronium

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