PXK
Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:611450 Ensembl IDEnsembl:ENSG00000168297 HGNC IDHGNC:HGNC:23326 PHARMGKB IDPA134899496 Map Location3p14.3 | |||||
GO terms in PXK
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | NAS | GO:0006468 | protein phosphorylation |
| BP | IMP | GO:0006954 | inflammatory response |
| BP | IBA | GO:0032780 | negative regulation of ATPase activity |
| BP | IBA | GO:0042391 | regulation of membrane potential |
| BP | IBA | GO:0043271 | negative regulation of ion transport |
| BP | ISS | GO:0050804 | modulation of chemical synaptic transmission |
Gene expression in normal tissue: PXK
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in PXK
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| No matching records found | ||
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in PXK
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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