iGMDRD177

Canonical SMILES: COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O

InChI: InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31-35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31+,32-/m0/s1

InChI Key: NRUKOCRGYNPUPR-QBPJDGROSA-N

Standard NameCHEMBLPubchem CIDKEGG Drug IDDRUGBANK IDDrug StatusDrug targets (TTD)Drug Type
TeniposideCHEMBL452231 452548D02698DB00444AloneDAP000651Small Molecule


Drug Targets:

TOP2A (P11388)TOP2B

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP2
4854NOTCH36
7514XPO11
8019BRD32
81037CLPTM1L3
10903MTMR113
7128TNFAIP31
5261PHKG22
132ADK3
5933RBL13
2986GUCY2F3
4627MYH96
5546PRCC4
150465TTL6
57554LRRC73
3845KRAS6
5295PIK3R13
8289ARID1A5
6351CCL41
3939LDHA2
83942TSSK1B2
9869SETDB15
4036LRP23
3069HDLBP3
9530BAG41
390502SERPINA23
6598SMARCB11
22853LMTK22
7253TSHR4
5298PI4KB6
2241FER4
341676NEK56
57172CAMK1G3
6318SERPINB41
9816URB23
6887TAL21
1387CREBBP4
5788PTPRC3
10013HDAC61
31ACACA4
9411ARHGAP294
8295TRRAP4
10438C1D9
11122PTPRT3
23617TSSK26
6722SRF3
5314PKHD15
4361MRE112
83439TCF7L13
1454CSNK1E3
54477PLEKHA52
57670KIAA15491
440279UNC13C8
342977NANOS35
9693RAPGEF23
1586CYP17A13
6256RXRA2
32ACACB2
4300MLLT32
8396PIP4K2B3
64083GOLPH31
2242FES3
8313AXIN24
1050CEBPA7
5330PLCB22
23255MTCL12
83990BRIP13
284217LAMA13
1143CHRNB42
4982TNFRSF11B2
2045EPHA72
1992SERPINB11
7078TIMP33
171019ADAMTS193
22858ICK1
65266WNK43
83983TSSK61
65217PCDH157
8395PIP5K1B2
6663SOX106
54899PXK4
29775CARD106
440730TRIM673
783CACNB23
92ACVR2A2
1452CSNK1A15
3685ITGAV2
6917TCEA13
139285AMER12
53942CNTN51
4087SMAD25
7010TEK2
898CCNE13
23152CIC3
157753TMEM744
7157TP531
79058ASPSCR12
2322FLT33
5910RAP1GDS13
4086SMAD11
65243ZFP69B3
105ADARB22
863CBFA2T34
8874ARHGEF71
1555CYP2B61
51086TNNI3K4
5597MAPK62
55437STRADB2
369ARAF2
9965FGF196
55589BMP2K3
65125WNK12
4436MSH22
50945TBX222
6035RNASE13
4026LPP5
8997KALRN4
2071ERCC36
3643INSR3
4089SMAD44
51284TLR73
54658UGT1A11
256536TCERG1L4
285220EPHA62
51366UBR53
3417IDH12
5606MAP2K31
2047EPHB13
64840PORCN3
440275EIF2AK46
2187FANCB1
6046BRD21
3720JARID26
2931GSK3A1
90ACVR11
2318FLNC2
57154SMURF12
7075TIE16
4609MYC1
4684NCAM15
29951PDZRN44
6776STAT5A4
833CARS3
7917BAG63
3949LDLR2
6872TAF15
203102ADAM321
1213CLTC3
23532PRAME2
57538ALPK36
8924HERC22
120892LRRK23
89795NAV33
65268WNK22
11126CD1606
6095RORA2
57507ZNF6083
5128CDK171
8626TP631
460ASTN13
4298MLLT12
9321TRIP114
664BNIP31
162968ZNF4973
23598PATZ11
10010TANK2
10752CHL13
57521RPTOR2
1487CTBP13
2316FLNA3
1869E2F13
6770STAR4
2648KAT2A1
85409NKD23
1676DFFA3
9344TAOK22
4055LTBR2
28954REM11
7454WAS5
55356SLC22A151
85415RHPN22
53904MYO3A2
9372ZFYVE93
8394PIP5K1A2
2353FOS2
4297KMT2A2
51151SLC45A23
5291PIK3CB2
558AXL2
4619MYH12
5581PRKCE3
317APAF13
9021SOCS33
10111RAD502
3181HNRNPA2B11
1281COL3A13
9201DCLK12
54101RIPK43
3557IL1RN4
131890GRK72
1385CREB16
8317CDC72
6778STAT62
4221MEN13
4772NFATC11
3656IRAK23
84072HORMAD12
2903GRIN2A2
5925RB15
4217MAP3K53
2074ERCC62
5324PLAG11
3691ITGB42
7403KDM6A6
7508XPC2
112268437LOC1122684373
3488IGFBP54
4915NTRK22
4299AFF13
2261FGFR32
23072HECW13
2073ERCC52
79966SCD51
4763NF14
55791LRIF14
1840DTX11
10891PPARGC1A4
440270GOLGA8B1
5287PIK3C2B3
30811HUNK3
7294TXK2
23112TNRC6B2
2178FANCE5
27255CNTN62
1499CTNNB14
2444FRK2
1795DOCK33
11035RIPK31
2904GRIN2B2
5624PROC2
5970RELA4

Gene in drug-gene network: Network Plot

Models in Teniposide

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