CNTN5
Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| contactin 5 | MIM:607219 | Ensembl:ENSG00000149972 | HGNC:HGNC:2175 | PA26689 | 11q22.1 |
GO terms in CNTN5
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0007155 | cell adhesion |
| BP | IEA | GO:0007605 | sensory perception of sound |
| CC | TAS | GO:0005576 | extracellular region |
| CC | IDA | GO:0005829 | cytosol |
| CC | TAS | GO:0005886 | plasma membrane |
| CC | IEA | GO:0031225 | anchored component of membrane |
Gene expression in normal tissue: CNTN5
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in CNTN5
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-163125 | Post-translational modification: synthesis of GPI-anchored proteins |
| reactome | R-HSA-392499 | Metabolism of proteins |
| reactome | R-HSA-597592 | Post-translational protein modification |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD889 | Compound 7d-cis | 5 |
| iGMDRD420 | Leucascandrolide A | 5 |
| iGMDRD772 | BRD4770 | 4 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD494 | Neopeltolide | 5 |
| iGMDRD781 | Sirolimus | 4 |
| iGMDRD144 | NSC95397 | 5 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD670 | ML 210 | 5 |
| iGMDRD152 | 179324-69-7 | 5 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD634 | SCHEMBL2608041 | 9 |
| iGMDRD255 | SB225002 | 3 |
| iGMDRD138 | PX 12 | 2 |
| iGMDRD474 | Avrainvillamide | 1 |
| iGMDRD885 | Compound 110 | 1 |
| iGMDRD441 | TW 37 | 2 |
| iGMDRD207 | Capsaicin | 2 |
| iGMDRD782 | DC-45-A2 | 3 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD399 | Selumetinib | 3 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD23 | Gossypol | 7 |
| iGMDRD60 | Quinoclamine | 1 |
| iGMDRD84 | Lovastatin acid | 2 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD405 | PIK-75 | 1 |
| iGMDRD701 | NVP-AUY922 | 1 |
| iGMDRD560 | MK-2206 | 4 |
| iGMDRD116 | CD437 | 1 |
| iGMDRD150 | RITA | 4 |
| iGMDRD424 | Tamatinib | 2 |
| iGMDRD499 | PDMP | 1 |
| iGMDRD57 | Chloropentafluorobenzene | 1 |
| iGMDRD341 | Triacsin c | 2 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 2 |
| iGMDRD211 | (1S,3R)-RSL3 | 5 |
| iGMDRD177 | Teniposide | 1 |
| iGMDRD103 | SN-38 | 3 |
| iGMDRD202 | Curcumin | 5 |
| iGMDRD251 | ML162 | 2 |
| iGMDRD77 | Itraconazole | 4 |
| iGMDRD267 | Oligomycin A | 6 |
| iGMDRD221 | Tamoxifen | 5 |
| iGMDRD6 | AM-580 | 3 |
| iGMDRD705 | Nakiterpiosin | 1 |
| iGMDRD329 | Merck60 | 4 |
| iGMDRD871 | BRD6368 | 4 |
| iGMDRD286 | Nsc 632839 | 6 |
| iGMDRD67 | PENFLURIDOL | 2 |
| iGMDRD872 | BRD7137 | 4 |
| iGMDRD82 | Quiflapon | 2 |
| iGMDRD300 | Tozasertib | 12 |
| iGMDRD263 | AACOCF3 | 1 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in CNTN5
CLASSFICATION
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