CNTN5


Summary: The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
OMIM IDMIM:607219
PHARMGKB IDPA26689
Map Location11q22.1

GO terms in CNTN5


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IEA GO:0007155 cell adhesion
BP IEA GO:0007605 sensory perception of sound
CC TAS GO:0005576 extracellular region
CC IDA GO:0005829 cytosol
CC TAS GO:0005886 plasma membrane
CC IEA GO:0031225 anchored component of membrane
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Gene expression in normal tissue: CNTN5

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined40Ferroptosis1PI3K/MTOR signaling1DNA replication1Stilbenoid, diarylheptanoid and gingerol biosynthesis1Mitosis1Drug metabolism - cytochrome P4501Protein stability and degradation1Biosynthesis of secondary metabolites1IGFR signaling1

Pathways in CNTN5


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Database
Pathway ID
Pathway Des.
reactome R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins
reactome R-HSA-392499 Metabolism of proteins
reactome R-HSA-597592 Post-translational protein modification
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD889 Compound 7d-cis 5
iGMDRD420 Leucascandrolide A 5
iGMDRD772 BRD4770 4
iGMDRD126 Tipifarnib 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in CNTN5

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
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