iGMDRD441
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| TW 37 | CHEMBL217354 | 11455900 | Alone | Small Molecule |
Drug Pathways:
Apoptosis regulationDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 3696 | ITGB8 | 1 |
| 64901 | RANBP17 | 1 |
| 9833 | MELK | 1 |
| 4854 | NOTCH3 | 3 |
| 7514 | XPO1 | 1 |
| 8999 | CDKL2 | 2 |
| 5027 | P2RX7 | 2 |
| 79054 | TRPM8 | 3 |
| 11183 | MAP4K5 | 5 |
| 2986 | GUCY2F | 2 |
| 2200 | FBN1 | 2 |
| 57679 | ALS2 | 5 |
| 1588 | CYP19A1 | 1 |
| 57554 | LRRC7 | 1 |
| 9149 | DYRK1B | 3 |
| 347365 | ITIH6 | 1 |
| 2100 | ESR2 | 1 |
| 4312 | MMP1 | 3 |
| 9475 | ROCK2 | 3 |
| 6597 | SMARCA4 | 1 |
| 4036 | LRP2 | 2 |
| 7764 | ZNF217 | 1 |
| 3069 | HDLBP | 5 |
| 10320 | IKZF1 | 2 |
| 79820 | CATSPERB | 2 |
| 5754 | PTK7 | 2 |
| 4313 | MMP2 | 2 |
| 23235 | SIK2 | 2 |
| 9891 | NUAK1 | 1 |
| 5218 | CDK14 | 3 |
| 23310 | NCAPD3 | 2 |
| 3841 | KPNA5 | 3 |
| 341676 | NEK5 | 1 |
| 9611 | NCOR1 | 1 |
| 2249 | FGF4 | 2 |
| 4881 | NPR1 | 1 |
| 5579 | PRKCB | 3 |
| 31 | ACACA | 2 |
| 51755 | CDK12 | 2 |
| 5966 | REL | 1 |
| 85021 | REPS1 | 2 |
| 8295 | TRRAP | 2 |
| 10295 | BCKDK | 6 |
| 2033 | EP300 | 5 |
| 8030 | CCDC6 | 3 |
| 4595 | MUTYH | 1 |
| 23522 | KAT6B | 5 |
| 22861 | NLRP1 | 1 |
| 4610 | MYCL | 2 |
| 4301 | AFDN | 4 |
| 816 | CAMK2B | 2 |
| 25937 | WWTR1 | 1 |
| 152137 | CCDC50 | 2 |
| 256646 | NUTM1 | 2 |
| 8767 | RIPK2 | 6 |
| 23012 | STK38L | 1 |
| 288 | ANK3 | 1 |
| 8549 | LGR5 | 2 |
| 32 | ACACB | 2 |
| 3091 | HIF1A | 1 |
| 200576 | PIKFYVE | 2 |
| 6733 | SRPK2 | 1 |
| 2042 | EPHA3 | 2 |
| 51343 | FZR1 | 1 |
| 9636 | ISG15 | 6 |
| 4216 | MAP3K4 | 1 |
| 83990 | BRIP1 | 1 |
| 6928 | HNF1B | 4 |
| 375449 | MAST4 | 1 |
| 85443 | DCLK3 | 3 |
| 6850 | SYK | 1 |
| 8452 | CUL3 | 1 |
| 79971 | WLS | 3 |
| 440730 | TRIM67 | 3 |
| 1456 | CSNK1G3 | 1 |
| 9131 | AIFM1 | 3 |
| 5580 | PRKCD | 1 |
| 6416 | MAP2K4 | 6 |
| 65987 | KCTD14 | 3 |
| 50488 | MINK1 | 3 |
| 80312 | TET1 | 3 |
| 5568 | PRKACG | 3 |
| 6098 | ROS1 | 6 |
| 638 | BIK | 3 |
| 3667 | IRS1 | 2 |
| 8148 | TAF15 | 4 |
| 575 | ADGRB1 | 4 |
| 53942 | CNTN5 | 2 |
| 3397 | ID1 | 1 |
| 7533 | YWHAH | 3 |
| 5289 | PIK3C3 | 4 |
| 5450 | POU2AF1 | 4 |
| 5327 | PLAT | 1 |
| 5863 | RGL2 | 2 |
| 9319 | TRIP13 | 3 |
| 2201 | FBN2 | 5 |
| 9794 | MAML1 | 3 |
| 959 | CD40LG | 3 |
| 83694 | RPS6KL1 | 3 |
| 28514 | DLL1 | 3 |
| 3932 | LCK | 4 |
| 58508 | KMT2C | 2 |
| 79058 | ASPSCR1 | 2 |
| 6794 | STK11 | 1 |
| 4857 | NOVA1 | 3 |
| 4292 | MLH1 | 2 |
| 2263 | FGFR2 | 1 |
| 4086 | SMAD1 | 1 |
| 2133 | EXT3 | 1 |
| 7249 | TSC2 | 1 |
| 9967 | THRAP3 | 4 |
| 1045 | CDX2 | 2 |
| 8874 | ARHGEF7 | 2 |
| 1102 | RCBTB2 | 2 |
| 6197 | RPS6KA3 | 1 |
| 4436 | MSH2 | 2 |
| 652 | BMP4 | 1 |
| 5871 | MAP4K2 | 6 |
| 80205 | CHD9 | 2 |
| 84181 | CHD6 | 1 |
| 8997 | KALRN | 3 |
| 23269 | MGA | 1 |
| 57111 | RAB25 | 1 |
| 4089 | SMAD4 | 1 |
| 54658 | UGT1A1 | 1 |
| 6654 | SOS1 | 1 |
| 10948 | STARD3 | 3 |
| 5727 | PTCH1 | 3 |
| 9448 | MAP4K4 | 3 |
| 5297 | PI4KA | 3 |
| 1978 | EIF4EBP1 | 1 |
| 57144 | PAK5 | 1 |
| 8216 | LZTR1 | 1 |
| 3702 | ITK | 2 |
| 5290 | PIK3CA | 4 |
| 4145 | MATK | 3 |
| 8202 | NCOA3 | 1 |
| 4293 | MAP3K9 | 2 |
| 26524 | LATS2 | 3 |
| 6391 | SDHC | 3 |
| 57154 | SMURF1 | 1 |
| 675 | BRCA2 | 3 |
| 4803 | NGF | 2 |
| 1956 | EGFR | 2 |
| 841 | CASP8 | 2 |
| 4609 | MYC | 1 |
| 64750 | SMURF2 | 2 |
| 5599 | MAPK8 | 3 |
| 7515 | XRCC1 | 1 |
| 1326 | MAP3K8 | 1 |
| 4684 | NCAM1 | 2 |
| 5592 | PRKG1 | 1 |
| 23005 | MAPKBP1 | 5 |
| 10186 | LHFPL6 | 3 |
| 84630 | TTBK1 | 4 |
| 22976 | PAXIP1 | 3 |
| 4863 | NPAT | 1 |
| 83452 | RAB33B | 2 |
| 57538 | ALPK3 | 3 |
| 2867 | FFAR2 | 3 |
| 146057 | TTBK2 | 3 |
| 5205 | ATP8B1 | 1 |
| 5128 | CDK17 | 1 |
| 23118 | TAB2 | 1 |
| 8626 | TP63 | 3 |
| 5979 | RET | 3 |
| 5378 | PMS1 | 1 |
| 9509 | ADAMTS2 | 4 |
| 23742 | NPAP1 | 2 |
| 23049 | SMG1 | 3 |
| 10010 | TANK | 2 |
| 5728 | PTEN | 2 |
| 1487 | CTBP1 | 3 |
| 7155 | TOP2B | 2 |
| 667 | DST | 6 |
| 1974 | EIF4A2 | 2 |
| 1950 | EGF | 1 |
| 91807 | MYLK3 | 1 |
| 79834 | PEAK1 | 2 |
| 85415 | RHPN2 | 2 |
| 8648 | NCOA1 | 1 |
| 387 | RHOA | 1 |
| 9372 | ZFYVE9 | 3 |
| 80184 | CEP290 | 1 |
| 8821 | INPP4B | 1 |
| 10595 | ERN2 | 2 |
| 51151 | SLC45A2 | 1 |
| 83417 | FCRL4 | 1 |
| 2869 | GRK5 | 2 |
| 5923 | RASGRF1 | 2 |
| 317 | APAF1 | 1 |
| 2690 | GHR | 2 |
| 9021 | SOCS3 | 2 |
| 100124696 | TEC | 1 |
| 53353 | LRP1B | 2 |
| 2185 | PTK2B | 3 |
| 283455 | KSR2 | 2 |
| 2194 | FASN | 6 |
| 3579 | CXCR2 | 3 |
| 5587 | PRKD1 | 1 |
| 5170 | PDPK1 | 1 |
| 2131 | EXT1 | 1 |
| 7099 | TLR4 | 3 |
| 6778 | STAT6 | 3 |
| 57118 | CAMK1D | 1 |
| 7112 | TMPO | 1 |
| 444 | ASPH | 3 |
| 2122 | MECOM | 2 |
| 3815 | KIT | 1 |
| 5925 | RB1 | 3 |
| 2065 | ERBB3 | 1 |
| 7403 | KDM6A | 3 |
| 30849 | PIK3R4 | 2 |
| 3716 | JAK1 | 3 |
| 2011 | MARK2 | 3 |
| 374 | AREG | 1 |
| 4763 | NF1 | 1 |
| 1612 | DAPK1 | 5 |
| 4591 | TRIM37 | 2 |
| 5287 | PIK3C2B | 1 |
| 4629 | MYH11 | 1 |
| 4193 | MDM2 | 1 |
| 27255 | CNTN6 | 2 |
| 1499 | CTNNB1 | 6 |
| 56155 | TEX14 | 5 |
| 5590 | PRKCZ | 1 |
Gene in drug-gene network: Network Plot
Models in TW 37
CLASSFICATION
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