WLS

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namewntless Wnt ligand secretion mediator
OMIM IDMIM:611514
Ensembl IDEnsembl:ENSG00000116729
HGNC IDHGNC:HGNC:30238
PHARMGKB IDPA165752781
Map Location1p31.3

GO terms in WLS


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IPI GO:0005515 protein binding
MF IBA GO:0017147 Wnt-protein binding
MF IPI GO:0017147 Wnt-protein binding
MF ISS GO:0017147 Wnt-protein binding
MF IEA GO:0031852 mu-type opioid receptor binding
CC TAS GO:0000139 Golgi membrane
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Gene expression in normal tissue: WLS

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined16Apoptosis regulation1PI3K/MTOR signaling1Biosynthesis of secondary metabolites1Drug metabolism - cytochrome P4501Protein stability and degradation1Proteasome1

Pathways in WLS


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Database
Pathway ID
Pathway Des.
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-195721 Signaling by WNT
reactome R-HSA-3238698 WNT ligand biogenesis and trafficking
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD433 Lexibulin 3
iGMDRD151 CHM-1 4
iGMDRD701 NVP-AUY922 3
iGMDRD446 LY 2183240 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in WLS

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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