iGMDRD433


Canonical SMILES: CCCC(C1=CN=CC=C1)NC2=NC(=NC=C2C)C3=CC(=C(C=C3)NC(=O)NCC)OC

InChI: InChI=1S/C24H30N6O2/c1-5-8-19(18-9-7-12-25-15-18)28-22-16(3)14-27-23(30-22)17-10-11-20(21(13-17)32-4)29-24(31)26-6-2/h7,9-15,19H,5-6,8H2,1-4H3,(H2,26,29,31)(H,27,28,30)/t19-/m0/s1

InChI Key: MTJHLONVHHPNSI-IBGZPJMESA-N

Standard NameCHEMBLPubchem CIDDrug StatusDrug Type
LexibulinCHEMBL552212 11351000AloneSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
64901RANBP172
1147CHUK4
1105CHD12
27125AFF44
8999CDKL25
5027P2RX75
6491STIL2
8476CDC42BPA1
26191PTPN223
2956MSH62
2200FBN11
57554LRRC72
3845KRAS1
4750NEK13
23097CDK193
55215FANCI1
8289ARID1A4
701BUB1B1
2475MTOR2
3326HSP90AB13
5133PDCD14
11116FGFR1OP1
7444VRK22
390502SERPINA23
10892MALT13
23235SIK24
10863ADAM282
3066HDAC21
55534MAML33
7048TGFBR23
80122MAP3K191
1387CREBBP4
1859DYRK1A4
11200CHEK24
51755CDK123
3604TNFRSF92
8295TRRAP3
10438C1D5
7173TPO2
55728N4BP25
54477PLEKHA54
57670KIAA15491
440279UNC13C2
4301AFDN2
84033OBSCN3
342977NANOS34
9693RAPGEF21
80351TNKS23
6091ROBO13
2042EPHA32
5330PLCB22
23255MTCL11
730249ACOD13
80129CCDC1703
83990BRIP13
4194MDM42
2045EPHA71
287015TRIM423
8643PTCH22
79971WLS3
54899PXK4
440730TRIM672
783CACNB23
6709SPTAN12
6464SHC12
80243PREX22
28996HIPK23
4087SMAD23
1496CTNNA23
2272FHIT2
2066ERBB44
7184HSP90B13
3932LCK3
58508KMT2C6
7157TP531
6092ROBO22
4173MCM41
4855NOTCH42
2322FLT33
8218CLTCL16
2263FGFR22
130399ACVR1C1
1019CDK43
11213IRAK34
55034MOCOS3
23043TNIK2
4436MSH22
80205CHD91
8997KALRN5
632BGLAP1
23469PHF33
4089SMAD44
6654SOS13
672BRCA14
11168PSIP11
7204TRIO1
10733PLK41
835CASP21
3417IDH13
5297PI4KA4
54756IL17RD3
4214MAP3K12
602BCL33
50615IL21R2
5290PIK3CA6
92335STRADA3
3720JARID26
26524LATS22
85366MYLK23
675BRCA24
3458IFNG3
26166RGS223
607BCL93
7075TIE12
744MPPED23
1956EGFR2
2735GLI13
64333ARHGAP91
11064CNTRL4
5789PTPRD6
8021NUP2142
26278SACS1
51265CDKL32
7443VRK12
91754NEK99
23005MAPKBP12
203102ADAM324
7153TOP2A3
1981EIF4G13
780DDR13
8924HERC23
339345NANOS21
120892LRRK26
6095RORA2
8029CUBN4
8626TP632
55521TRIM363
10752CHL13
23476BRD41
4914NTRK13
22883CLSTN12
667DST4
115701ALPK22
6770STAR3
177AGER3
3899AFF33
7273TTN4
7059THBS33
85415RHPN21
10562OLFM43
54904NSD33
387RHOA2
54861SNRK3
55561CDC42BPG3
10249GLYAT2
286151FBXO433
26686OR4E23
7248TSC12
9748SLK3
4619MYH13
57680CHD83
5562PRKAA13
1399CRKL3
2317FLNB3
10111RAD503
1281COL3A16
9659PDE4DIP5
54101RIPK43
6760SS183
5927KDM5A6
5589PRKCSH4
57448BIRC61
3717JAK23
2157F82
3977LIFR1
2122MECOM2
63923TNN1
4638MYLK6
30849PIK3R42
2261FGFR35
23072HECW13
55422ZNF3315
4763NF12
2044EPHA51
4593MUSK3
30811HUNK2
81788NUAK21
23112TNRC6B2
2178FANCE1
2892GRIA33

Gene in drug-gene network: Network Plot

Models in Lexibulin

​​​​