SS18
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| SS18, nBAF chromatin remodeling complex subunit | MIM:600192 | Ensembl:ENSG00000141380 | HGNC:HGNC:11340 | PA36164 | 18q11.2 |
Gene Categories:
DRUG RESISTANCEGO terms in SS18
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | TAS | GO:0005634 | nucleus |
| CC | IEA | GO:0005881 | cytoplasmic microtubule |
| CC | IEA | GO:0071564 | npBAF complex |
| BP | IEA | GO:0000226 | microtubule cytoskeleton organization |
| BP | IEA | GO:0000902 | cell morphogenesis |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0035556 | intracellular signal transduction |
| BP | IEA | GO:0042493 | response to drug |
| BP | IBA | GO:0045893 | positive regulation of transcription, DNA-templated |
| BP | IBA | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| BP | IDA | GO:0045944 | positive regulation of transcription by RNA polymerase II |
| BP | IEA | GO:0048013 | ephrin receptor signaling pathway |
| BP | IEA | GO:0097150 | neuronal stem cell population maintenance |
| MF | IBA | GO:0003712 | transcription coregulator activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IDA | GO:0030374 | nuclear receptor transcription coactivator activity |
Gene expression in normal tissue: SS18
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SS18
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05202 | Transcriptional misregulation in cancer - Homo sapiens (human) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD670 | ML 210 | 2 |
| iGMDRD405 | PIK-75 | 2 |
| iGMDRD433 | Lexibulin | 3 |
| iGMDRD137 | Indisulam | 4 |
| iGMDRD202 | Curcumin | 5 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD1008 | SR-II-138A | 1 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD451 | Serdemetan | 3 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD399 | Selumetinib | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SS18
CLASSFICATION
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