iGMDRD137
Standard Name | CHEMBL | Pubchem CID | DRUGBANK ID | Drug Status | Drug Type |
---|---|---|---|---|---|
Indisulam | CHEMBL77517 | 216468 | DB06370 | Alone | Small Molecule |
Drug Targets:
CA9Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
Gene ID | Gene Name | Model Num. |
---|---|---|
3696 | ITGB8 | 1 |
64901 | RANBP17 | 5 |
27102 | EIF2AK1 | 3 |
4854 | NOTCH3 | 2 |
3725 | JUN | 6 |
5296 | PIK3R2 | 3 |
81037 | CLPTM1L | 4 |
5027 | P2RX7 | 6 |
10903 | MTMR11 | 6 |
3159 | HMGA1 | 3 |
79054 | TRPM8 | 2 |
10221 | TRIB1 | 3 |
9261 | MAPKAPK2 | 3 |
21 | ABCA3 | 2 |
132 | ADK | 5 |
6774 | STAT3 | 3 |
6195 | RPS6KA1 | 2 |
7750 | ZMYM2 | 1 |
4066 | LYL1 | 3 |
11183 | MAP4K5 | 5 |
2048 | EPHB2 | 3 |
4627 | MYH9 | 6 |
5546 | PRCC | 3 |
4168 | MCF2 | 1 |
2956 | MSH6 | 3 |
150465 | TTL | 6 |
10783 | NEK6 | 4 |
1588 | CYP19A1 | 6 |
1520 | CTSS | 5 |
1969 | EPHA2 | 10 |
9706 | ULK2 | 2 |
9149 | DYRK1B | 1 |
817 | CAMK2D | 6 |
7272 | TTK | 2 |
1138 | CHRNA5 | 2 |
3757 | KCNH2 | 2 |
23552 | CDK20 | 2 |
23097 | CDK19 | 3 |
8289 | ARID1A | 2 |
137994 | LETM2 | 4 |
8266 | UBL4A | 1 |
701 | BUB1B | 3 |
25778 | DSTYK | 3 |
84700 | MYO18B | 3 |
4928 | NUP98 | 4 |
79092 | CARD14 | 1 |
9760 | TOX | 2 |
4352 | MPL | 4 |
2161 | F12 | 3 |
2475 | MTOR | 3 |
1263 | PLK3 | 2 |
6597 | SMARCA4 | 2 |
3551 | IKBKB | 3 |
81035 | COLEC12 | 6 |
9869 | SETDB1 | 5 |
10395 | DLC1 | 1 |
5241 | PGR | 3 |
5133 | PDCD1 | 7 |
3069 | HDLBP | 3 |
10320 | IKZF1 | 2 |
4094 | MAF | 2 |
6657 | SOX2 | 1 |
390502 | SERPINA2 | 5 |
23495 | TNFRSF13B | 3 |
56776 | FMN2 | 4 |
64783 | RBM15 | 3 |
10892 | MALT1 | 8 |
4313 | MMP2 | 2 |
23235 | SIK2 | 4 |
10863 | ADAM28 | 1 |
6598 | SMARCB1 | 1 |
4170 | MCL1 | 2 |
23213 | SULF1 | 3 |
3320 | HSP90AA1 | 1 |
3066 | HDAC2 | 1 |
10142 | AKAP9 | 6 |
22853 | LMTK2 | 3 |
55781 | RIOK2 | 3 |
23310 | NCAPD3 | 3 |
5298 | PI4KB | 8 |
8749 | ADAM18 | 4 |
3841 | KPNA5 | 3 |
2241 | FER | 1 |
55534 | MAML3 | 1 |
9816 | URB2 | 2 |
84299 | MIEN1 | 1 |
6887 | TAL2 | 6 |
140469 | MYO3B | 3 |
604 | BCL6 | 2 |
2249 | FGF4 | 2 |
54822 | TRPM7 | 2 |
51199 | NIN | 2 |
577 | ADGRB3 | 6 |
28231 | SLCO4A1 | 3 |
114783 | LMTK3 | 2 |
202374 | STK32A | 5 |
11329 | STK38 | 2 |
26039 | SS18L1 | 2 |
2043 | EPHA4 | 2 |
55023 | PHIP | 1 |
2885 | GRB2 | 5 |
10013 | HDAC6 | 1 |
7133 | TNFRSF1B | 3 |
1602 | DACH1 | 4 |
10178 | TENM1 | 2 |
9699 | RIMS2 | 2 |
51755 | CDK12 | 5 |
79858 | NEK11 | 2 |
9048 | ARTN | 6 |
5533 | PPP3CC | 3 |
57472 | CNOT6 | 3 |
5966 | REL | 5 |
3604 | TNFRSF9 | 2 |
8295 | TRRAP | 2 |
1111 | CHEK1 | 3 |
10438 | C1D | 10 |
11122 | PTPRT | 4 |
23617 | TSSK2 | 3 |
7373 | COL14A1 | 4 |
55300 | PI4K2B | 2 |
7173 | TPO | 6 |
5605 | MAP2K2 | 3 |
139378 | ADGRG4 | 2 |
55294 | FBXW7 | 3 |
2033 | EP300 | 2 |
6927 | HNF1A | 3 |
8784 | TNFRSF18 | 3 |
4361 | MRE11 | 2 |
10746 | MAP3K2 | 2 |
64324 | NSD1 | 3 |
83439 | TCF7L1 | 2 |
1021 | CDK6 | 3 |
23522 | KAT6B | 2 |
55728 | N4BP2 | 1 |
3227 | HOXC11 | 3 |
1453 | CSNK1D | 3 |
10006 | ABI1 | 2 |
25925 | ZNF521 | 2 |
54477 | PLEKHA5 | 2 |
57670 | KIAA1549 | 5 |
22861 | NLRP1 | 2 |
284521 | OR2L13 | 3 |
440279 | UNC13C | 2 |
4301 | AFDN | 2 |
55819 | RNF130 | 3 |
5900 | RALGDS | 1 |
51776 | MAP3K20 | 3 |
256646 | NUTM1 | 3 |
2268 | FGR | 9 |
11073 | TOPBP1 | 2 |
388228 | SBK1 | 3 |
122011 | CSNK1A1L | 1 |
2051 | EPHB6 | 7 |
6418 | SET | 3 |
6256 | RXRA | 2 |
3714 | JAG2 | 1 |
3556 | IL1RAP | 5 |
2688 | GH1 | 6 |
166614 | DCLK2 | 3 |
7416 | VDAC1 | 2 |
22984 | PDCD11 | 4 |
6041 | RNASEL | 1 |
5468 | PPARG | 2 |
200576 | PIKFYVE | 2 |
6733 | SRPK2 | 3 |
1050 | CEBPA | 2 |
4792 | NFKBIA | 3 |
2260 | FGFR1 | 6 |
51343 | FZR1 | 4 |
5330 | PLCB2 | 3 |
114548 | NLRP3 | 3 |
5984 | RFC4 | 2 |
10188 | TNK2 | 12 |
9636 | ISG15 | 4 |
10217 | CTDSPL | 5 |
11169 | WDHD1 | 2 |
695 | BTK | 2 |
2908 | NR3C1 | 2 |
51804 | SIX4 | 9 |
4739 | NEDD9 | 6 |
4194 | MDM4 | 4 |
7088 | TLE1 | 3 |
269 | AMHR2 | 2 |
2045 | EPHA7 | 4 |
1992 | SERPINB1 | 4 |
238 | ALK | 2 |
1277 | COL1A1 | 2 |
7078 | TIMP3 | 1 |
375449 | MAST4 | 3 |
22858 | ICK | 3 |
65266 | WNK4 | 2 |
287015 | TRIM42 | 5 |
83983 | TSSK6 | 1 |
8643 | PTCH2 | 1 |
65217 | PCDH15 | 4 |
3916 | LAMP1 | 6 |
6663 | SOX10 | 6 |
26750 | RPS6KC1 | 2 |
29775 | CARD10 | 6 |
23191 | CYFIP1 | 4 |
440730 | TRIM67 | 6 |
23387 | SIK3 | 3 |
783 | CACNB2 | 2 |
9759 | HDAC4 | 5 |
92 | ACVR2A | 4 |
1452 | CSNK1A1 | 2 |
29760 | BLNK | 5 |
8714 | ABCC3 | 3 |
5286 | PIK3C2A | 2 |
6709 | SPTAN1 | 2 |
1973 | EIF4A1 | 1 |
1909 | EDNRA | 2 |
10087 | COL4A3BP | 3 |
50488 | MINK1 | 5 |
5591 | PRKDC | 4 |
79705 | LRRK1 | 3 |
5568 | PRKACG | 3 |
6464 | SHC1 | 2 |
7166 | TPH1 | 2 |
54437 | SEMA5B | 3 |
6917 | TCEA1 | 8 |
51433 | ANAPC5 | 3 |
472 | ATM | 6 |
1009 | CDH11 | 4 |
139285 | AMER1 | 4 |
8148 | TAF15 | 3 |
28996 | HIPK2 | 1 |
575 | ADGRB1 | 11 |
5924 | RASGRF2 | 5 |
4087 | SMAD2 | 3 |
9564 | BCAR1 | 5 |
4804 | NGFR | 3 |
4058 | LTK | 4 |
54986 | ULK4 | 4 |
7010 | TEK | 3 |
5289 | PIK3C3 | 2 |
5450 | POU2AF1 | 4 |
91461 | PKDCC | 3 |
23152 | CIC | 3 |
2272 | FHIT | 3 |
7867 | MAPKAPK3 | 6 |
2066 | ERBB4 | 2 |
839 | CASP6 | 3 |
5863 | RGL2 | 2 |
10290 | SPEG | 1 |
79442 | LRRC2 | 3 |
1029 | CDKN2A | 6 |
7184 | HSP90B1 | 2 |
10062 | NR1H3 | 2 |
5108 | PCM1 | 3 |
5460 | POU5F1 | 3 |
5129 | CDK18 | 2 |
157753 | TMEM74 | 3 |
8576 | STK16 | 3 |
1910 | EDNRB | 3 |
3932 | LCK | 3 |
58508 | KMT2C | 3 |
7157 | TP53 | 8 |
6092 | ROBO2 | 3 |
79058 | ASPSCR1 | 3 |
4855 | NOTCH4 | 5 |
57194 | ATP10A | 6 |
7869 | SEMA3B | 2 |
8218 | CLTCL1 | 3 |
147746 | HIPK4 | 3 |
2263 | FGFR2 | 5 |
5585 | PKN1 | 7 |
7249 | TSC2 | 6 |
7409 | VAV1 | 3 |
65243 | ZFP69B | 6 |
1045 | CDX2 | 3 |
64386 | MMP25 | 3 |
863 | CBFA2T3 | 2 |
23043 | TNIK | 2 |
5600 | MAPK11 | 3 |
55437 | STRADB | 4 |
7038 | TG | 2 |
369 | ARAF | 3 |
4921 | DDR2 | 1 |
8660 | IRS2 | 6 |
3572 | IL6ST | 3 |
55589 | BMP2K | 6 |
65125 | WNK1 | 3 |
57591 | MRTFA | 3 |
136332 | LRGUK | 3 |
50945 | TBX22 | 3 |
652 | BMP4 | 3 |
6035 | RNASE1 | 3 |
676 | BRDT | 5 |
5650 | KLK7 | 3 |
7175 | TPR | 2 |
5871 | MAP4K2 | 3 |
9401 | RECQL4 | 3 |
54106 | TLR9 | 3 |
3718 | JAK3 | 6 |
23365 | ARHGEF12 | 3 |
84181 | CHD6 | 3 |
8997 | KALRN | 3 |
4437 | MSH3 | 2 |
2071 | ERCC3 | 4 |
23269 | MGA | 9 |
5888 | RAD51 | 3 |
2175 | FANCA | 5 |
23469 | PHF3 | 2 |
51284 | TLR7 | 6 |
6654 | SOS1 | 9 |
672 | BRCA1 | 7 |
2668 | GDNF | 6 |
10948 | STARD3 | 1 |
7204 | TRIO | 3 |
835 | CASP2 | 8 |
5727 | PTCH1 | 2 |
285220 | EPHA6 | 2 |
3417 | IDH1 | 5 |
23678 | SGK3 | 2 |
5606 | MAP2K3 | 5 |
5297 | PI4KA | 2 |
2047 | EPHB1 | 3 |
5069 | PAPPA | 5 |
7786 | MAP3K12 | 3 |
10769 | PLK2 | 2 |
64840 | PORCN | 2 |
30827 | CXXC1 | 4 |
5578 | PRKCA | 3 |
4214 | MAP3K1 | 3 |
440275 | EIF2AK4 | 3 |
1198 | CLK3 | 2 |
2187 | FANCB | 1 |
5290 | PIK3CA | 3 |
92335 | STRADA | 4 |
6046 | BRD2 | 6 |
3720 | JARID2 | 3 |
1514 | CTSL | 5 |
2931 | GSK3A | 4 |
1687 | GSDME | 3 |
90 | ACVR1 | 3 |
5366 | PMAIP1 | 1 |
5045 | FURIN | 2 |
2318 | FLNC | 10 |
10565 | ARFGEF1 | 2 |
57154 | SMURF1 | 7 |
2030 | SLC29A1 | 3 |
675 | BRCA2 | 7 |
607 | BCL9 | 2 |
10155 | TRIM28 | 3 |
7075 | TIE1 | 2 |
1956 | EGFR | 1 |
640 | BLK | 2 |
157680 | VPS13B | 2 |
2735 | GLI1 | 2 |
3065 | HDAC1 | 3 |
4609 | MYC | 3 |
11064 | CNTRL | 6 |
90956 | ADCK2 | 3 |
2624 | GATA2 | 3 |
5789 | PTPRD | 3 |
5155 | PDGFB | 6 |
8013 | NR4A3 | 2 |
90427 | BMF | 3 |
1326 | MAP3K8 | 3 |
4684 | NCAM1 | 5 |
26278 | SACS | 5 |
6776 | STAT5A | 3 |
833 | CARS | 3 |
5592 | PRKG1 | 3 |
1594 | CYP27B1 | 5 |
5156 | PDGFRA | 2 |
3635 | INPP5D | 3 |
7917 | BAG6 | 2 |
375056 | MIA3 | 6 |
10971 | YWHAQ | 4 |
1544 | CYP1A2 | 3 |
9159 | PCSK7 | 3 |
27330 | RPS6KA6 | 2 |
3949 | LDLR | 5 |
10186 | LHFPL6 | 1 |
203102 | ADAM32 | 3 |
673 | BRAF | 3 |
7153 | TOP2A | 3 |
1213 | CLTC | 5 |
988 | CDC5L | 3 |
3315 | HSPB1 | 3 |
23532 | PRAME | 1 |
4863 | NPAT | 5 |
780 | DDR1 | 2 |
83452 | RAB33B | 2 |
57538 | ALPK3 | 1 |
8924 | HERC2 | 2 |
6469 | SHH | 3 |
339345 | NANOS2 | 1 |
120892 | LRRK2 | 5 |
89795 | NAV3 | 3 |
65268 | WNK2 | 3 |
694 | BTG1 | 2 |
6095 | RORA | 11 |
29844 | TFPT | 3 |
146057 | TTBK2 | 3 |
84441 | MAML2 | 2 |
5128 | CDK17 | 3 |
9113 | LATS1 | 2 |
460 | ASTN1 | 3 |
9064 | MAP3K6 | 3 |
5294 | PIK3CG | 9 |
4298 | MLLT1 | 2 |
5979 | RET | 2 |
9321 | TRIP11 | 7 |
9451 | EIF2AK3 | 6 |
2017 | CTTN | 3 |
664 | BNIP3 | 1 |
4853 | NOTCH2 | 6 |
1230 | CCR1 | 2 |
9509 | ADAMTS2 | 5 |
23049 | SMG1 | 3 |
10010 | TANK | 3 |
8312 | AXIN1 | 6 |
55521 | TRIM36 | 8 |
10752 | CHL1 | 3 |
23476 | BRD4 | 1 |
5728 | PTEN | 1 |
1487 | CTBP1 | 3 |
7030 | TFE3 | 4 |
2316 | FLNA | 2 |
4914 | NTRK1 | 3 |
22883 | CLSTN1 | 7 |
667 | DST | 3 |
3554 | IL1R1 | 2 |
2897 | GRIK1 | 2 |
140803 | TRPM6 | 3 |
6146 | RPL22 | 5 |
10962 | MLLT11 | 2 |
2264 | FGFR4 | 2 |
177 | AGER | 1 |
658 | BMPR1B | 2 |
5896 | RAG1 | 3 |
23090 | ZNF423 | 3 |
3899 | AFF3 | 3 |
6498 | SKIL | 3 |
7273 | TTN | 2 |
1445 | CSK | 3 |
79834 | PEAK1 | 7 |
7465 | WEE1 | 3 |
3577 | CXCR1 | 3 |
348378 | SHISAL2A | 3 |
7454 | WAS | 1 |
85415 | RHPN2 | 2 |
8028 | MLLT10 | 3 |
55359 | STYK1 | 3 |
8667 | EIF3H | 3 |
387 | RHOA | 3 |
3161 | HMMR | 1 |
55561 | CDC42BPG | 3 |
128869 | PIGU | 3 |
8821 | INPP4B | 4 |
221895 | JAZF1 | 2 |
84930 | MASTL | 4 |
9943 | OXSR1 | 2 |
22843 | PPM1E | 1 |
8394 | PIP5K1A | 2 |
2353 | FOS | 5 |
26686 | OR4E2 | 4 |
23305 | ACSL6 | 2 |
1643 | DDB2 | 1 |
54738 | FEV | 3 |
344905 | ATP13A5 | 1 |
51151 | SLC45A2 | 2 |
5291 | PIK3CB | 2 |
1493 | CTLA4 | 5 |
10076 | PTPRU | 1 |
7248 | TSC1 | 4 |
9748 | SLK | 2 |
4619 | MYH1 | 1 |
2932 | GSK3B | 4 |
57680 | CHD8 | 6 |
5581 | PRKCE | 3 |
5923 | RASGRF1 | 6 |
2317 | FLNB | 3 |
10111 | RAD50 | 2 |
6790 | AURKA | 3 |
5395 | PMS2 | 1 |
860 | RUNX2 | 3 |
778 | CACNA1F | 1 |
53353 | LRP1B | 4 |
7094 | TLN1 | 3 |
9659 | PDE4DIP | 4 |
9201 | DCLK1 | 4 |
4000 | LMNA | 2 |
2049 | EPHB3 | 3 |
3557 | IL1RN | 5 |
5335 | PLCG1 | 1 |
6760 | SS18 | 4 |
2130 | EWSR1 | 2 |
131890 | GRK7 | 3 |
2194 | FASN | 2 |
4628 | MYH10 | 3 |
5927 | KDM5A | 5 |
55007 | FAM118A | 1 |
1719 | DHFR | 2 |
57448 | BIRC6 | 3 |
2131 | EXT1 | 1 |
2304 | FOXE1 | 2 |
8317 | CDC7 | 2 |
22982 | DIP2C | 6 |
53335 | BCL11A | 6 |
6778 | STAT6 | 2 |
1906 | EDN1 | 3 |
8899 | PRPF4B | 2 |
6194 | RPS6 | 3 |
1030 | CDKN2B | 3 |
65267 | WNK3 | 6 |
150094 | SIK1 | 1 |
84254 | CAMKK1 | 1 |
4772 | NFATC1 | 3 |
6777 | STAT5B | 2 |
80216 | ALPK1 | 5 |
5932 | RBBP8 | 1 |
5915 | RARB | 1 |
4261 | CIITA | 2 |
84072 | HORMAD1 | 8 |
170685 | NUDT10 | 3 |
11076 | TPPP | 3 |
2122 | MECOM | 1 |
5087 | PBX1 | 4 |
3815 | KIT | 9 |
2903 | GRIN2A | 3 |
5925 | RB1 | 3 |
4217 | MAP3K5 | 3 |
5584 | PRKCI | 2 |
63923 | TNN | 3 |
415116 | PIM3 | 9 |
2074 | ERCC6 | 2 |
3131 | HLF | 2 |
862 | RUNX1T1 | 3 |
7403 | KDM6A | 1 |
54790 | TET2 | 3 |
2308 | FOXO1 | 2 |
2534 | FYN | 2 |
81629 | TSSK3 | 2 |
7508 | XPC | 2 |
8841 | HDAC3 | 4 |
4302 | MLLT6 | 3 |
4638 | MYLK | 11 |
4205 | MEF2A | 3 |
30849 | PIK3R4 | 1 |
9878 | TOX4 | 6 |
3480 | IGF1R | 4 |
79728 | PALB2 | 3 |
23092 | ARHGAP26 | 6 |
374 | AREG | 3 |
2261 | FGFR3 | 2 |
139604 | MAGEB16 | 8 |
3237 | HOXD11 | 3 |
2073 | ERCC5 | 3 |
5567 | PRKACB | 1 |
55422 | ZNF331 | 3 |
79966 | SCD5 | 3 |
8321 | FZD1 | 3 |
595 | CCND1 | 3 |
4763 | NF1 | 3 |
55791 | LRIF1 | 3 |
9625 | AATK | 3 |
4613 | MYCN | 3 |
494551 | WEE2 | 2 |
1840 | DTX1 | 5 |
10891 | PPARGC1A | 3 |
440270 | GOLGA8B | 3 |
4593 | MUSK | 2 |
3110 | MNX1 | 3 |
2246 | FGF1 | 3 |
23683 | PRKD3 | 2 |
7294 | TXK | 1 |
6868 | ADAM17 | 2 |
23112 | TNRC6B | 2 |
4738 | NEDD8 | 3 |
27255 | CNTN6 | 2 |
83732 | RIOK1 | 3 |
1499 | CTNNB1 | 4 |
2444 | FRK | 7 |
27151 | CPAMD8 | 3 |
56155 | TEX14 | 3 |
5602 | MAPK10 | 2 |
1795 | DOCK3 | 2 |
167359 | NIM1K | 1 |
1488 | CTBP2 | 3 |
Gene in drug-gene network: Network Plot
Models in Indisulam