iGMDRD137


Canonical SMILES: C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl

InChI: InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)

InChI Key: SETFNECMODOHTO-UHFFFAOYSA-N

Standard NameCHEMBLPubchem CIDDRUGBANK IDDrug StatusDrug Type
IndisulamCHEMBL77517 216468DB06370AloneSmall Molecule


Drug Targets:

CA9

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
3696ITGB81
64901RANBP175
27102EIF2AK13
4854NOTCH32
3725JUN6
5296PIK3R23
81037CLPTM1L4
5027P2RX76
10903MTMR116
3159HMGA13
79054TRPM82
10221TRIB13
9261MAPKAPK23
21ABCA32
132ADK5
6774STAT33
6195RPS6KA12
7750ZMYM21
4066LYL13
11183MAP4K55
2048EPHB23
4627MYH96
5546PRCC3
4168MCF21
2956MSH63
150465TTL6
10783NEK64
1588CYP19A16
1520CTSS5
1969EPHA210
9706ULK22
9149DYRK1B1
817CAMK2D6
7272TTK2
1138CHRNA52
3757KCNH22
23552CDK202
23097CDK193
8289ARID1A2
137994LETM24
8266UBL4A1
701BUB1B3
25778DSTYK3
84700MYO18B3
4928NUP984
79092CARD141
9760TOX2
4352MPL4
2161F123
2475MTOR3
1263PLK32
6597SMARCA42
3551IKBKB3
81035COLEC126
9869SETDB15
10395DLC11
5241PGR3
5133PDCD17
3069HDLBP3
10320IKZF12
4094MAF2
6657SOX21
390502SERPINA25
23495TNFRSF13B3
56776FMN24
64783RBM153
10892MALT18
4313MMP22
23235SIK24
10863ADAM281
6598SMARCB11
4170MCL12
23213SULF13
3320HSP90AA11
3066HDAC21
10142AKAP96
22853LMTK23
55781RIOK23
23310NCAPD33
5298PI4KB8
8749ADAM184
3841KPNA53
2241FER1
55534MAML31
9816URB22
84299MIEN11
6887TAL26
140469MYO3B3
604BCL62
2249FGF42
54822TRPM72
51199NIN2
577ADGRB36
28231SLCO4A13
114783LMTK32
202374STK32A5
11329STK382
26039SS18L12
2043EPHA42
55023PHIP1
2885GRB25
10013HDAC61
7133TNFRSF1B3
1602DACH14
10178TENM12
9699RIMS22
51755CDK125
79858NEK112
9048ARTN6
5533PPP3CC3
57472CNOT63
5966REL5
3604TNFRSF92
8295TRRAP2
1111CHEK13
10438C1D10
11122PTPRT4
23617TSSK23
7373COL14A14
55300PI4K2B2
7173TPO6
5605MAP2K23
139378ADGRG42
55294FBXW73
2033EP3002
6927HNF1A3
8784TNFRSF183
4361MRE112
10746MAP3K22
64324NSD13
83439TCF7L12
1021CDK63
23522KAT6B2
55728N4BP21
3227HOXC113
1453CSNK1D3
10006ABI12
25925ZNF5212
54477PLEKHA52
57670KIAA15495
22861NLRP12
284521OR2L133
440279UNC13C2
4301AFDN2
55819RNF1303
5900RALGDS1
51776MAP3K203
256646NUTM13
2268FGR9
11073TOPBP12
388228SBK13
122011CSNK1A1L1
2051EPHB67
6418SET3
6256RXRA2
3714JAG21
3556IL1RAP5
2688GH16
166614DCLK23
7416VDAC12
22984PDCD114
6041RNASEL1
5468PPARG2
200576PIKFYVE2
6733SRPK23
1050CEBPA2
4792NFKBIA3
2260FGFR16
51343FZR14
5330PLCB23
114548NLRP33
5984RFC42
10188TNK212
9636ISG154
10217CTDSPL5
11169WDHD12
695BTK2
2908NR3C12
51804SIX49
4739NEDD96
4194MDM44
7088TLE13
269AMHR22
2045EPHA74
1992SERPINB14
238ALK2
1277COL1A12
7078TIMP31
375449MAST43
22858ICK3
65266WNK42
287015TRIM425
83983TSSK61
8643PTCH21
65217PCDH154
3916LAMP16
6663SOX106
26750RPS6KC12
29775CARD106
23191CYFIP14
440730TRIM676
23387SIK33
783CACNB22
9759HDAC45
92ACVR2A4
1452CSNK1A12
29760BLNK5
8714ABCC33
5286PIK3C2A2
6709SPTAN12
1973EIF4A11
1909EDNRA2
10087COL4A3BP3
50488MINK15
5591PRKDC4
79705LRRK13
5568PRKACG3
6464SHC12
7166TPH12
54437SEMA5B3
6917TCEA18
51433ANAPC53
472ATM6
1009CDH114
139285AMER14
8148TAF153
28996HIPK21
575ADGRB111
5924RASGRF25
4087SMAD23
9564BCAR15
4804NGFR3
4058LTK4
54986ULK44
7010TEK3
5289PIK3C32
5450POU2AF14
91461PKDCC3
23152CIC3
2272FHIT3
7867MAPKAPK36
2066ERBB42
839CASP63
5863RGL22
10290SPEG1
79442LRRC23
1029CDKN2A6
7184HSP90B12
10062NR1H32
5108PCM13
5460POU5F13
5129CDK182
157753TMEM743
8576STK163
1910EDNRB3
3932LCK3
58508KMT2C3
7157TP538
6092ROBO23
79058ASPSCR13
4855NOTCH45
57194ATP10A6
7869SEMA3B2
8218CLTCL13
147746HIPK43
2263FGFR25
5585PKN17
7249TSC26
7409VAV13
65243ZFP69B6
1045CDX23
64386MMP253
863CBFA2T32
23043TNIK2
5600MAPK113
55437STRADB4
7038TG2
369ARAF3
4921DDR21
8660IRS26
3572IL6ST3
55589BMP2K6
65125WNK13
57591MRTFA3
136332LRGUK3
50945TBX223
652BMP43
6035RNASE13
676BRDT5
5650KLK73
7175TPR2
5871MAP4K23
9401RECQL43
54106TLR93
3718JAK36
23365ARHGEF123
84181CHD63
8997KALRN3
4437MSH32
2071ERCC34
23269MGA9
5888RAD513
2175FANCA5
23469PHF32
51284TLR76
6654SOS19
672BRCA17
2668GDNF6
10948STARD31
7204TRIO3
835CASP28
5727PTCH12
285220EPHA62
3417IDH15
23678SGK32
5606MAP2K35
5297PI4KA2
2047EPHB13
5069PAPPA5
7786MAP3K123
10769PLK22
64840PORCN2
30827CXXC14
5578PRKCA3
4214MAP3K13
440275EIF2AK43
1198CLK32
2187FANCB1
5290PIK3CA3
92335STRADA4
6046BRD26
3720JARID23
1514CTSL5
2931GSK3A4
1687GSDME3
90ACVR13
5366PMAIP11
5045FURIN2
2318FLNC10
10565ARFGEF12
57154SMURF17
2030SLC29A13
675BRCA27
607BCL92
10155TRIM283
7075TIE12
1956EGFR1
640BLK2
157680VPS13B2
2735GLI12
3065HDAC13
4609MYC3
11064CNTRL6
90956ADCK23
2624GATA23
5789PTPRD3
5155PDGFB6
8013NR4A32
90427BMF3
1326MAP3K83
4684NCAM15
26278SACS5
6776STAT5A3
833CARS3
5592PRKG13
1594CYP27B15
5156PDGFRA2
3635INPP5D3
7917BAG62
375056MIA36
10971YWHAQ4
1544CYP1A23
9159PCSK73
27330RPS6KA62
3949LDLR5
10186LHFPL61
203102ADAM323
673BRAF3
7153TOP2A3
1213CLTC5
988CDC5L3
3315HSPB13
23532PRAME1
4863NPAT5
780DDR12
83452RAB33B2
57538ALPK31
8924HERC22
6469SHH3
339345NANOS21
120892LRRK25
89795NAV33
65268WNK23
694BTG12
6095RORA11
29844TFPT3
146057TTBK23
84441MAML22
5128CDK173
9113LATS12
460ASTN13
9064MAP3K63
5294PIK3CG9
4298MLLT12
5979RET2
9321TRIP117
9451EIF2AK36
2017CTTN3
664BNIP31
4853NOTCH26
1230CCR12
9509ADAMTS25
23049SMG13
10010TANK3
8312AXIN16
55521TRIM368
10752CHL13
23476BRD41
5728PTEN1
1487CTBP13
7030TFE34
2316FLNA2
4914NTRK13
22883CLSTN17
667DST3
3554IL1R12
2897GRIK12
140803TRPM63
6146RPL225
10962MLLT112
2264FGFR42
177AGER1
658BMPR1B2
5896RAG13
23090ZNF4233
3899AFF33
6498SKIL3
7273TTN2
1445CSK3
79834PEAK17
7465WEE13
3577CXCR13
348378SHISAL2A3
7454WAS1
85415RHPN22
8028MLLT103
55359STYK13
8667EIF3H3
387RHOA3
3161HMMR1
55561CDC42BPG3
128869PIGU3
8821INPP4B4
221895JAZF12
84930MASTL4
9943OXSR12
22843PPM1E1
8394PIP5K1A2
2353FOS5
26686OR4E24
23305ACSL62
1643DDB21
54738FEV3
344905ATP13A51
51151SLC45A22
5291PIK3CB2
1493CTLA45
10076PTPRU1
7248TSC14
9748SLK2
4619MYH11
2932GSK3B4
57680CHD86
5581PRKCE3
5923RASGRF16
2317FLNB3
10111RAD502
6790AURKA3
5395PMS21
860RUNX23
778CACNA1F1
53353LRP1B4
7094TLN13
9659PDE4DIP4
9201DCLK14
4000LMNA2
2049EPHB33
3557IL1RN5
5335PLCG11
6760SS184
2130EWSR12
131890GRK73
2194FASN2
4628MYH103
5927KDM5A5
55007FAM118A1
1719DHFR2
57448BIRC63
2131EXT11
2304FOXE12
8317CDC72
22982DIP2C6
53335BCL11A6
6778STAT62
1906EDN13
8899PRPF4B2
6194RPS63
1030CDKN2B3
65267WNK36
150094SIK11
84254CAMKK11
4772NFATC13
6777STAT5B2
80216ALPK15
5932RBBP81
5915RARB1
4261CIITA2
84072HORMAD18
170685NUDT103
11076TPPP3
2122MECOM1
5087PBX14
3815KIT9
2903GRIN2A3
5925RB13
4217MAP3K53
5584PRKCI2
63923TNN3
415116PIM39
2074ERCC62
3131HLF2
862RUNX1T13
7403KDM6A1
54790TET23
2308FOXO12
2534FYN2
81629TSSK32
7508XPC2
8841HDAC34
4302MLLT63
4638MYLK11
4205MEF2A3
30849PIK3R41
9878TOX46
3480IGF1R4
79728PALB23
23092ARHGAP266
374AREG3
2261FGFR32
139604MAGEB168
3237HOXD113
2073ERCC53
5567PRKACB1
55422ZNF3313
79966SCD53
8321FZD13
595CCND13
4763NF13
55791LRIF13
9625AATK3
4613MYCN3
494551WEE22
1840DTX15
10891PPARGC1A3
440270GOLGA8B3
4593MUSK2
3110MNX13
2246FGF13
23683PRKD32
7294TXK1
6868ADAM172
23112TNRC6B2
4738NEDD83
27255CNTN62
83732RIOK13
1499CTNNB14
2444FRK7
27151CPAMD83
56155TEX143
5602MAPK102
1795DOCK32
167359NIM1K1
1488CTBP23

Gene in drug-gene network: Network Plot

Models in Indisulam

​​​​