LAMP1

Summary: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Namelysosomal associated membrane protein 1
OMIM IDMIM:153330
Ensembl IDEnsembl:ENSG00000185896
HGNC IDHGNC:HGNC:6499
PHARMGKB IDPA30283
Map Location13q34

GO terms in LAMP1


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Term Type
Evidence Type
GO Term ID
GO Des.
BP IMP GO:0008626 granzyme-mediated apoptotic signaling pathway
BP TAS GO:0043312 neutrophil degranulation
BP IMP GO:0043323 positive regulation of natural killer cell degranulation
BP IMP GO:0045954 positive regulation of natural killer cell mediated cytotoxicity
BP IEA GO:0046718 viral entry into host cell
BP IEA GO:0048102 autophagic cell death
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Gene expression in normal tissue: LAMP1

Gene-model tissue-cancer distribution: Bubble Plot

LUNtissue: LUN cancer: LUNG model num: 0LUNGtissue: LUNG cancer: undefined model num: 12BLOOtissue: BLOO cancer: BLOOD model num: 0BLOODtissue: BLOOD cancer: undefined model num: 3undefinetissue: undefine cancer: undefined model num: 0undefinedtissue: undefined cancer: PANCAN model num: 29

Gene-drug pathway distribution

undefined9PI3K/MTOR signaling2DNA replication1Cell cycle1Apoptosis regulation1Protein stability and degradation1

Pathways in LAMP1


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Database
Pathway ID
Pathway Des.
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-6798695 Neutrophil degranulation
wikipathways WP615 Senescence and Autophagy in Cancer
kegg hsa04140 Autophagy - animal - Homo sapiens (human)
kegg hsa04142 Lysosome - Homo sapiens (human)
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD123 Isoevodiamine 3
iGMDRD64 Parbendazole 3
iGMDRD562 Navitoclax 3
iGMDRD193 Fqi1 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in LAMP1

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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