iGMDRD560
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| MK-2206 | CHEMBL1079175 | 24964600 | Alone | Small Molecule |
Drug Pathways:
PI3K/MTOR signalingDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 1147 | CHUK | 6 |
| 7128 | TNFAIP3 | 1 |
| 6581 | SLC22A3 | 4 |
| 8915 | BCL10 | 3 |
| 8476 | CDC42BPA | 2 |
| 7750 | ZMYM2 | 2 |
| 11183 | MAP4K5 | 3 |
| 4627 | MYH9 | 1 |
| 4168 | MCF2 | 2 |
| 7171 | TPM4 | 3 |
| 3708 | ITPR1 | 3 |
| 3845 | KRAS | 1 |
| 2100 | ESR2 | 1 |
| 8289 | ARID1A | 3 |
| 5593 | PRKG2 | 4 |
| 53616 | ADAM22 | 7 |
| 9760 | TOX | 3 |
| 2475 | MTOR | 2 |
| 6597 | SMARCA4 | 2 |
| 150209 | AIFM3 | 1 |
| 7764 | ZNF217 | 3 |
| 7444 | VRK2 | 3 |
| 5079 | PAX5 | 3 |
| 64783 | RBM15 | 2 |
| 57580 | PREX1 | 1 |
| 10892 | MALT1 | 2 |
| 4313 | MMP2 | 3 |
| 23235 | SIK2 | 2 |
| 1786 | DNMT1 | 3 |
| 6598 | SMARCB1 | 1 |
| 3694 | ITGB6 | 2 |
| 3320 | HSP90AA1 | 3 |
| 7253 | TSHR | 1 |
| 23310 | NCAPD3 | 3 |
| 7098 | TLR3 | 3 |
| 10645 | CAMKK2 | 3 |
| 341676 | NEK5 | 2 |
| 1404 | HAPLN1 | 3 |
| 577 | ADGRB3 | 1 |
| 80122 | MAP3K19 | 1 |
| 28231 | SLCO4A1 | 3 |
| 5788 | PTPRC | 3 |
| 5579 | PRKCB | 1 |
| 1602 | DACH1 | 3 |
| 9048 | ARTN | 2 |
| 5596 | MAPK4 | 2 |
| 2625 | GATA3 | 1 |
| 2977 | GUCY1A2 | 2 |
| 27148 | STK36 | 3 |
| 7158 | TP53BP1 | 1 |
| 89910 | UBE3B | 2 |
| 10295 | BCKDK | 3 |
| 2033 | EP300 | 5 |
| 23522 | KAT6B | 6 |
| 22861 | NLRP1 | 1 |
| 284521 | OR2L13 | 3 |
| 440279 | UNC13C | 3 |
| 4301 | AFDN | 1 |
| 8767 | RIPK2 | 6 |
| 3621 | ING1 | 4 |
| 2051 | EPHB6 | 3 |
| 169436 | STKLD1 | 3 |
| 32 | ACACB | 3 |
| 4300 | MLLT3 | 2 |
| 8396 | PIP4K2B | 3 |
| 64083 | GOLPH3 | 1 |
| 6091 | ROBO1 | 3 |
| 116986 | AGAP2 | 3 |
| 5330 | PLCB2 | 2 |
| 23255 | MTCL1 | 2 |
| 9636 | ISG15 | 3 |
| 10298 | PAK4 | 3 |
| 3688 | ITGB1 | 3 |
| 9098 | USP6 | 1 |
| 284217 | LAMA1 | 2 |
| 207 | AKT1 | 1 |
| 2045 | EPHA7 | 2 |
| 23405 | DICER1 | 2 |
| 1277 | COL1A1 | 1 |
| 171019 | ADAMTS19 | 1 |
| 375449 | MAST4 | 3 |
| 2064 | ERBB2 | 2 |
| 3916 | LAMP1 | 3 |
| 993 | CDC25A | 2 |
| 1456 | CSNK1G3 | 6 |
| 4140 | MARK3 | 3 |
| 6416 | MAP2K4 | 7 |
| 9759 | HDAC4 | 3 |
| 1909 | EDNRA | 1 |
| 5591 | PRKDC | 4 |
| 8859 | STK19 | 3 |
| 79705 | LRRK1 | 3 |
| 6037 | RNASE3 | 3 |
| 8515 | ITGA10 | 2 |
| 3667 | IRS1 | 1 |
| 8945 | BTRC | 3 |
| 2580 | GAK | 2 |
| 3418 | IDH2 | 3 |
| 575 | ADGRB1 | 2 |
| 2521 | FUS | 3 |
| 53942 | CNTN5 | 4 |
| 5924 | RASGRF2 | 1 |
| 8038 | ADAM12 | 3 |
| 898 | CCNE1 | 1 |
| 28951 | TRIB2 | 3 |
| 10413 | YAP1 | 1 |
| 5834 | PYGB | 1 |
| 58508 | KMT2C | 1 |
| 7157 | TP53 | 1 |
| 4292 | MLH1 | 2 |
| 6772 | STAT1 | 3 |
| 93210 | PGAP3 | 3 |
| 54498 | SMOX | 1 |
| 5585 | PKN1 | 2 |
| 9639 | ARHGEF10 | 2 |
| 84075 | FSCB | 3 |
| 9967 | THRAP3 | 2 |
| 85481 | PSKH2 | 3 |
| 8833 | GMPS | 3 |
| 5604 | MAP2K1 | 3 |
| 55034 | MOCOS | 3 |
| 5600 | MAPK11 | 2 |
| 2309 | FOXO3 | 3 |
| 9965 | FGF19 | 3 |
| 57188 | ADAMTSL3 | 5 |
| 3187 | HNRNPH1 | 2 |
| 57591 | MRTFA | 2 |
| 4436 | MSH2 | 5 |
| 9401 | RECQL4 | 3 |
| 2081 | ERN1 | 3 |
| 2071 | ERCC3 | 3 |
| 2175 | FANCA | 3 |
| 8288 | EPX | 3 |
| 54658 | UGT1A1 | 1 |
| 3559 | IL2RA | 3 |
| 672 | BRCA1 | 1 |
| 11168 | PSIP1 | 2 |
| 4139 | MARK1 | 4 |
| 7204 | TRIO | 6 |
| 10733 | PLK4 | 2 |
| 23373 | CRTC1 | 3 |
| 3417 | IDH1 | 2 |
| 30827 | CXXC1 | 3 |
| 340533 | NEXMIF | 6 |
| 5290 | PIK3CA | 2 |
| 3720 | JARID2 | 2 |
| 7075 | TIE1 | 2 |
| 8445 | DYRK2 | 3 |
| 640 | BLK | 2 |
| 4609 | MYC | 1 |
| 1459 | CSNK2A2 | 2 |
| 894 | CCND2 | 4 |
| 1440 | CSF3 | 3 |
| 5747 | PTK2 | 2 |
| 5187 | PER1 | 3 |
| 7917 | BAG6 | 1 |
| 10000 | AKT3 | 1 |
| 7153 | TOP2A | 2 |
| 1769 | DNAH8 | 3 |
| 23532 | PRAME | 3 |
| 83452 | RAB33B | 2 |
| 57538 | ALPK3 | 2 |
| 8924 | HERC2 | 2 |
| 2078 | ERG | 2 |
| 339345 | NANOS2 | 2 |
| 65268 | WNK2 | 3 |
| 11126 | CD160 | 3 |
| 29844 | TFPT | 2 |
| 7301 | TYRO3 | 1 |
| 7468 | NSD2 | 2 |
| 4298 | MLLT1 | 3 |
| 162968 | ZNF497 | 3 |
| 9509 | ADAMTS2 | 2 |
| 23396 | PIP5K1C | 2 |
| 10010 | TANK | 1 |
| 5728 | PTEN | 5 |
| 208 | AKT2 | 4 |
| 115701 | ALPK2 | 1 |
| 3554 | IL1R1 | 1 |
| 83666 | PARP9 | 3 |
| 5305 | PIP4K2A | 2 |
| 2897 | GRIK1 | 1 |
| 352909 | DNAAF3 | 2 |
| 6770 | STAR | 2 |
| 2870 | GRK6 | 3 |
| 9344 | TAOK2 | 3 |
| 23090 | ZNF423 | 2 |
| 4055 | LTBR | 2 |
| 28954 | REM1 | 1 |
| 2277 | VEGFD | 3 |
| 23411 | SIRT1 | 3 |
| 53904 | MYO3A | 2 |
| 54861 | SNRK | 3 |
| 22843 | PPM1E | 2 |
| 65018 | PINK1 | 3 |
| 1643 | DDB2 | 3 |
| 4297 | KMT2A | 2 |
| 4619 | MYH1 | 1 |
| 3297 | HSF1 | 3 |
| 5923 | RASGRF1 | 4 |
| 4774 | NFIA | 1 |
| 81608 | FIP1L1 | 3 |
| 2690 | GHR | 6 |
| 54101 | RIPK4 | 3 |
| 283455 | KSR2 | 2 |
| 6093 | ROCK1 | 3 |
| 1385 | CREB1 | 3 |
| 5587 | PRKD1 | 3 |
| 5589 | PRKCSH | 2 |
| 5170 | PDPK1 | 2 |
| 2131 | EXT1 | 3 |
| 8317 | CDC7 | 3 |
| 3717 | JAK2 | 3 |
| 5506 | PPP1R3A | 2 |
| 57147 | SCYL3 | 2 |
| 4221 | MEN1 | 4 |
| 8899 | PRPF4B | 3 |
| 23301 | EHBP1 | 2 |
| 100862685 | ERVK-19 | 1 |
| 3516 | RBPJ | 2 |
| 80216 | ALPK1 | 4 |
| 4261 | CIITA | 1 |
| 444 | ASPH | 2 |
| 2122 | MECOM | 3 |
| 5584 | PRKCI | 2 |
| 2065 | ERBB3 | 2 |
| 10420 | TESK2 | 2 |
| 9878 | TOX4 | 1 |
| 171017 | ZNF384 | 3 |
| 11086 | ADAM29 | 3 |
| 142 | PARP1 | 2 |
| 2073 | ERCC5 | 2 |
| 5567 | PRKACB | 2 |
| 4040 | LRP6 | 2 |
| 55422 | ZNF331 | 1 |
| 1013 | CDH15 | 3 |
| 4841 | NONO | 3 |
| 8321 | FZD1 | 3 |
| 1994 | ELAVL1 | 3 |
| 4613 | MYCN | 3 |
| 57096 | RPGRIP1 | 1 |
| 1608 | DGKG | 3 |
| 7294 | TXK | 3 |
| 4738 | NEDD8 | 3 |
| 27151 | CPAMD8 | 2 |
| 2892 | GRIA3 | 2 |
| 11035 | RIPK3 | 2 |
Gene in drug-gene network: Network Plot
Models in MK-2206
CLASSFICATION
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