AIFM3
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| apoptosis inducing factor, mitochondria associated 3 | MIM:617298 | Ensembl:ENSG00000183773 | HGNC:HGNC:26398 | PA162376173 | 22q11.21 |
Gene Categories:
DRUGGABLE GENOMEGO terms in AIFM3
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IEA | GO:0016491 | oxidoreductase activity |
| MF | IEA | GO:0046872 | metal ion binding |
| MF | IEA | GO:0050660 | flavin adenine dinucleotide binding |
| MF | IEA | GO:0051537 | 2 iron, 2 sulfur cluster binding |
| CC | IDA | GO:0005634 | nucleus |
| CC | IDA | GO:0005739 | mitochondrion |
| CC | IDA | GO:0005743 | mitochondrial inner membrane |
| CC | IDA | GO:0005783 | endoplasmic reticulum |
| CC | IDA | GO:0005829 | cytosol |
| BP | IEA | GO:0055114 | oxidation-reduction process |
| BP | IDA | GO:0097194 | execution phase of apoptosis |
Gene expression in normal tissue: AIFM3
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in AIFM3
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD679 | Bistramide A | 6 |
| iGMDRD435 | BI-2536 | 2 |
| iGMDRD341 | Triacsin c | 1 |
| iGMDRD446 | LY 2183240 | 2 |
| iGMDRD351 | GW843682X | 1 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD560 | MK-2206 | 1 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD889 | Compound 7d-cis | 4 |
| iGMDRD772 | BRD4770 | 1 |
| iGMDRD60 | Quinoclamine | 1 |
| iGMDRD552 | AZD-1775 | 1 |
| iGMDRD369 | TGX-115 | 3 |
| iGMDRD871 | BRD6368 | 1 |
| iGMDRD414 | MST-312 | 3 |
| iGMDRD188 | Piperlongumine | 1 |
| iGMDRD366 | PI-103 | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in AIFM3
CLASSFICATION
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