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iGMDRD369

Canonical SMILES: CC1=CC=CC=C1OC2=CC=CC3=C2NC(=CC3=O)N4CCOCC4

InChI: InChI=1S/C20H20N2O3/c1-14-5-2-3-7-17(14)25-18-8-4-6-15-16(23)13-19(21-20(15)18)22-9-11-24-12-10-22/h2-8,13H,9-12H2,1H3,(H,21,23)

InChI Key: FWYYZGLCNUZWPF-UHFFFAOYSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
TGX-115	9902310	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
1147	CHUK	2
7128	TNFAIP3	4
21	ABCA3	3
7421	VDR	3
11183	MAP4K5	2
5546	PRCC	3
2200	FBN1	2
57554	LRRC7	3
3845	KRAS	1
1138	CHRNA5	3
4750	NEK1	3
8289	ARID1A	2
80070	ADAMTS20	2
701	BUB1B	1
2335	FN1	3
79092	CARD14	2
150209	AIFM3	3
79820	CATSPERB	2
5079	PAX5	3
10892	MALT1	2
23235	SIK2	2
9891	NUAK1	3
23213	SULF1	3
3320	HSP90AA1	4
9641	IKBKE	3
22853	LMTK2	3
7253	TSHR	4
7098	TLR3	3
10645	CAMKK2	3
3841	KPNA5	3
341676	NEK5	2
6318	SERPINB4	2
1387	CREBBP	2
5579	PRKCB	3
1602	DACH1	2
9048	ARTN	2
2977	GUCY1A2	1
11122	PTPRT	1
139378	ADGRG4	3
89910	UBE3B	2
55294	FBXW7	1
10295	BCKDK	3
57787	MARK4	2
169436	STKLD1	3
6256	RXRA	3
4300	MLLT3	3
64083	GOLPH3	2
22806	IKZF3	3
3645	INSRR	3
22984	PDCD11	3
9175	MAP3K13	2
8313	AXIN2	2
2260	FGFR1	3
51343	FZR1	2
5330	PLCB2	2
23255	MTCL1	2
80129	CCDC170	2
10298	PAK4	3
51804	SIX4	2
9098	USP6	2
375449	MAST4	3
993	CDC25A	2
4140	MARK3	2
9759	HDAC4	3
80243	PREX2	2
1009	CDH11	3
575	ADGRB1	2
7533	YWHAH	3
8798	DYRK4	3
4173	MCM4	2
4602	MYB	2
10114	HIPK3	3
54498	SMOX	1
2133	EXT3	3
572	BAD	3
84075	FSCB	3
9967	THRAP3	3
4869	NPM1	2
55034	MOCOS	3
10516	FBLN5	2
7038	TG	2
9965	FGF19	3
57188	ADAMTSL3	5
57591	MRTFA	2
136332	LRGUK	2
4436	MSH2	1
652	BMP4	5
9401	RECQL4	3
4437	MSH3	3
2071	ERCC3	1
2175	FANCA	2
4139	MARK1	3
7204	TRIO	2
23373	CRTC1	3
9448	MAP4K4	3
285220	EPHA6	1
3417	IDH1	2
2047	EPHB1	2
30827	CXXC1	3
4214	MAP3K1	2
8202	NCOA3	3
4293	MAP3K9	2
26524	LATS2	1
64919	BCL11B	3
675	BRCA2	2
1956	EGFR	4
11064	CNTRL	3
90956	ADCK2	3
26278	SACS	2
29951	PDZRN4	1
6776	STAT5A	3
833	CARS	3
7015	TERT	3
23532	PRAME	2
83452	RAB33B	2
2078	ERG	2
339345	NANOS2	2
29844	TFPT	2
460	ASTN1	3
162968	ZNF497	3
9509	ADAMTS2	3
1806	DPYD	3
23476	BRD4	3
7030	TFE3	2
7155	TOP2B	2
667	DST	1
284086	NEK8	2
5305	PIP4K2A	2
28954	REM1	3
53904	MYO3A	1
65018	PINK1	3
558	AXL	3
5923	RASGRF1	3
53353	LRP1B	2
283455	KSR2	3
6093	ROCK1	3
3557	IL1RN	3
3624	INHBA	3
2194	FASN	3
1385	CREB1	3
1719	DHFR	3
5170	PDPK1	2
6196	RPS6KA2	3
8317	CDC7	3
5506	PPP1R3A	1
3709	ITPR2	3
57147	SCYL3	2
23301	EHBP1	2
8428	STK24	3
4772	NFATC1	2
3516	RBPJ	2
80216	ALPK1	1
4261	CIITA	2
11076	TPPP	2
2122	MECOM	1
51167	CYB5R4	3
10420	TESK2	2
54790	TET2	6
3716	JAK1	3
1013	CDH15	3
4763	NF1	1
8814	CDKL1	3
1612	DAPK1	3
1994	ELAVL1	3
63893	UBE2O	2
494551	WEE2	3
4629	MYH11	3
1795	DOCK3	3
11035	RIPK3	2

Gene in drug-gene network: Network Plot

Models in TGX-115

SITE

DATATYPES

CLASSFICATION

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