iGMDRD369


Canonical SMILES: CC1=CC=CC=C1OC2=CC=CC3=C2NC(=CC3=O)N4CCOCC4

InChI: InChI=1S/C20H20N2O3/c1-14-5-2-3-7-17(14)25-18-8-4-6-15-16(23)13-19(21-20(15)18)22-9-11-24-12-10-22/h2-8,13H,9-12H2,1H3,(H,21,23)

InChI Key: FWYYZGLCNUZWPF-UHFFFAOYSA-N

Standard NamePubchem CIDDrug StatusDrug Type
TGX-1159902310AloneSmall Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
1147CHUK2
7128TNFAIP34
21ABCA33
7421VDR3
11183MAP4K52
5546PRCC3
2200FBN12
57554LRRC73
3845KRAS1
1138CHRNA53
4750NEK13
8289ARID1A2
80070ADAMTS202
701BUB1B1
2335FN13
79092CARD142
150209AIFM33
79820CATSPERB2
5079PAX53
10892MALT12
23235SIK22
9891NUAK13
23213SULF13
3320HSP90AA14
9641IKBKE3
22853LMTK23
7253TSHR4
7098TLR33
10645CAMKK23
3841KPNA53
341676NEK52
6318SERPINB42
1387CREBBP2
5579PRKCB3
1602DACH12
9048ARTN2
2977GUCY1A21
11122PTPRT1
139378ADGRG43
89910UBE3B2
55294FBXW71
10295BCKDK3
57787MARK42
169436STKLD13
6256RXRA3
4300MLLT33
64083GOLPH32
22806IKZF33
3645INSRR3
22984PDCD113
9175MAP3K132
8313AXIN22
2260FGFR13
51343FZR12
5330PLCB22
23255MTCL12
80129CCDC1702
10298PAK43
51804SIX42
9098USP62
375449MAST43
993CDC25A2
4140MARK32
9759HDAC43
80243PREX22
1009CDH113
575ADGRB12
7533YWHAH3
8798DYRK43
4173MCM42
4602MYB2
10114HIPK33
54498SMOX1
2133EXT33
572BAD3
84075FSCB3
9967THRAP33
4869NPM12
55034MOCOS3
10516FBLN52
7038TG2
9965FGF193
57188ADAMTSL35
57591MRTFA2
136332LRGUK2
4436MSH21
652BMP45
9401RECQL43
4437MSH33
2071ERCC31
2175FANCA2
4139MARK13
7204TRIO2
23373CRTC13
9448MAP4K43
285220EPHA61
3417IDH12
2047EPHB12
30827CXXC13
4214MAP3K12
8202NCOA33
4293MAP3K92
26524LATS21
64919BCL11B3
675BRCA22
1956EGFR4
11064CNTRL3
90956ADCK23
26278SACS2
29951PDZRN41
6776STAT5A3
833CARS3
7015TERT3
23532PRAME2
83452RAB33B2
2078ERG2
339345NANOS22
29844TFPT2
460ASTN13
162968ZNF4973
9509ADAMTS23
1806DPYD3
23476BRD43
7030TFE32
7155TOP2B2
667DST1
284086NEK82
5305PIP4K2A2
28954REM13
53904MYO3A1
65018PINK13
558AXL3
5923RASGRF13
53353LRP1B2
283455KSR23
6093ROCK13
3557IL1RN3
3624INHBA3
2194FASN3
1385CREB13
1719DHFR3
5170PDPK12
6196RPS6KA23
8317CDC73
5506PPP1R3A1
3709ITPR23
57147SCYL32
23301EHBP12
8428STK243
4772NFATC12
3516RBPJ2
80216ALPK11
4261CIITA2
11076TPPP2
2122MECOM1
51167CYB5R43
10420TESK22
54790TET26
3716JAK13
1013CDH153
4763NF11
8814CDKL13
1612DAPK13
1994ELAVL13
63893UBE2O2
494551WEE23
4629MYH113
1795DOCK33
11035RIPK32

Gene in drug-gene network: Network Plot

Models in TGX-115

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