USP6


Summary:

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
ubiquitin specific peptidase 6MIM:604334Ensembl:ENSG00000129204HGNC:HGNC:12629PA3725417p13.2

Gene Categories:

DRUGGABLE GENOMEPROTEASE

GO terms in USP6


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005737cytoplasm
CCTASGO:0005764lysosome
CCIDAGO:0005886plasma membrane
CCIDAGO:0055037recycling endosome
BPNASGO:0006464cellular protein modification process
BPIEAGO:0006511ubiquitin-dependent protein catabolic process
BPIBAGO:0006886intracellular protein transport
BPIDAGO:0016579protein deubiquitination
BPIDAGO:0060627regulation of vesicle-mediated transport
BPIBAGO:0090630activation of GTPase activity
MFTASGO:0003676nucleic acid binding
MFTASGO:0004197cysteine-type endopeptidase activity
MFIDAGO:0004843thiol-dependent ubiquitin-specific protease activity
MFIBAGO:0005096GTPase activator activity
MFIPIGO:0005515protein binding
MFIEAGO:0005516calmodulin binding
MFIBAGO:0017137Rab GTPase binding

Gene expression in normal tissue: USP6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in USP6


DatabasePathway IDPathway Des.
pidarf6_pathwayArf6 signaling events

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD560MK-22061
iGMDRD427ABT7372
iGMDRD781Sirolimus4
iGMDRD126Tipifarnib2
iGMDRD387CHIR-990212
iGMDRD123Isoevodiamine2
iGMDRD341Triacsin c9
iGMDRD237ABT-7512
iGMDRD61Kinetin riboside7
iGMDRD6AM-5804
iGMDRD434BMS-5369243
iGMDRD481Dactolisib2
iGMDRD733SGC09461
iGMDRD187BRD98762
iGMDRD474Avrainvillamide2
iGMDRD158NSC1415402
iGMDRD369TGX-1152
iGMDRD64Parbendazole1
iGMDRD60Quinoclamine2
iGMDRD100Zebularine1
iGMDRD67PENFLURIDOL3
iGMDRD188Piperlongumine2
iGMDRD399Selumetinib2
iGMDRD577BIX012942

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in USP6

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