USP6

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameubiquitin specific peptidase 6
OMIM IDMIM:604334
Ensembl IDEnsembl:ENSG00000129204
HGNC IDHGNC:HGNC:12629
PHARMGKB IDPA37254
Map Location17p13.2

Gene Categories:

DRUGGABLE GENOMEPROTEASE

GO terms in USP6


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IDA GO:0005737 cytoplasm
CC TAS GO:0005764 lysosome
CC IDA GO:0005886 plasma membrane
CC IDA GO:0055037 recycling endosome
BP NAS GO:0006464 cellular protein modification process
BP IEA GO:0006511 ubiquitin-dependent protein catabolic process
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Gene expression in normal tissue: USP6

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined17PI3K/MTOR signaling2ERK MAPK signaling1DNA replication1WNT signaling1Longevity regulating pathway1Chromatin histone methylation1

Pathways in USP6


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Database
Pathway ID
Pathway Des.
pid arf6_pathway Arf6 signaling events
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD560 MK-2206 1
iGMDRD427 ABT737 2
iGMDRD781 Sirolimus 4
iGMDRD126 Tipifarnib 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in USP6

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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