iGMDRD123
| Standard Name | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|
| Isoevodiamine | 151289 | Alone | Small Molecule |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 2 |
| 3696 | ITGB8 | 3 |
| 64901 | RANBP17 | 1 |
| 1105 | CHD1 | 2 |
| 4854 | NOTCH3 | 3 |
| 8999 | CDKL2 | 4 |
| 5296 | PIK3R2 | 3 |
| 5027 | P2RX7 | 6 |
| 10903 | MTMR11 | 4 |
| 471 | ATIC | 3 |
| 79054 | TRPM8 | 1 |
| 1464 | CSPG4 | 5 |
| 10641 | NPRL2 | 3 |
| 6491 | STIL | 2 |
| 5261 | PHKG2 | 2 |
| 8444 | DYRK3 | 3 |
| 9261 | MAPKAPK2 | 2 |
| 21 | ABCA3 | 5 |
| 132 | ADK | 3 |
| 8476 | CDC42BPA | 4 |
| 7750 | ZMYM2 | 5 |
| 11183 | MAP4K5 | 3 |
| 79947 | DHDDS | 3 |
| 4627 | MYH9 | 1 |
| 5546 | PRCC | 3 |
| 4168 | MCF2 | 3 |
| 2956 | MSH6 | 4 |
| 57679 | ALS2 | 3 |
| 150465 | TTL | 1 |
| 3708 | ITPR1 | 2 |
| 10783 | NEK6 | 3 |
| 7272 | TTK | 2 |
| 3845 | KRAS | 4 |
| 3757 | KCNH2 | 8 |
| 4750 | NEK1 | 7 |
| 5295 | PIK3R1 | 2 |
| 23097 | CDK19 | 6 |
| 55215 | FANCI | 3 |
| 8289 | ARID1A | 2 |
| 701 | BUB1B | 2 |
| 5934 | RBL2 | 2 |
| 84700 | MYO18B | 2 |
| 4928 | NUP98 | 1 |
| 9760 | TOX | 2 |
| 4352 | MPL | 3 |
| 6938 | TCF12 | 3 |
| 2475 | MTOR | 4 |
| 1263 | PLK3 | 2 |
| 9475 | ROCK2 | 3 |
| 83942 | TSSK1B | 3 |
| 6597 | SMARCA4 | 1 |
| 3551 | IKBKB | 3 |
| 3326 | HSP90AB1 | 3 |
| 9869 | SETDB1 | 2 |
| 4036 | LRP2 | 3 |
| 8780 | RIOK3 | 3 |
| 11160 | ERLIN2 | 1 |
| 10395 | DLC1 | 2 |
| 5241 | PGR | 1 |
| 5133 | PDCD1 | 10 |
| 843 | CASP10 | 3 |
| 11116 | FGFR1OP | 2 |
| 7444 | VRK2 | 5 |
| 7942 | TFEB | 3 |
| 6657 | SOX2 | 3 |
| 390502 | SERPINA2 | 3 |
| 5754 | PTK7 | 2 |
| 64783 | RBM15 | 4 |
| 51684 | SUFU | 3 |
| 10892 | MALT1 | 6 |
| 4313 | MMP2 | 1 |
| 23235 | SIK2 | 3 |
| 10863 | ADAM28 | 2 |
| 6598 | SMARCB1 | 6 |
| 4170 | MCL1 | 4 |
| 1607 | DGKB | 1 |
| 23213 | SULF1 | 3 |
| 1272 | CNTN1 | 1 |
| 3066 | HDAC2 | 8 |
| 10142 | AKAP9 | 2 |
| 7253 | TSHR | 6 |
| 7098 | TLR3 | 3 |
| 10645 | CAMKK2 | 3 |
| 2241 | FER | 5 |
| 55534 | MAML3 | 1 |
| 1404 | HAPLN1 | 6 |
| 22821 | RASA3 | 4 |
| 9816 | URB2 | 3 |
| 6455 | SH3GL1 | 3 |
| 1545 | CYP1B1 | 3 |
| 140469 | MYO3B | 3 |
| 604 | BCL6 | 1 |
| 80122 | MAP3K19 | 3 |
| 1387 | CREBBP | 5 |
| 8106 | PABPN1 | 3 |
| 2043 | EPHA4 | 3 |
| 55023 | PHIP | 7 |
| 1859 | DYRK1A | 1 |
| 5467 | PPARD | 3 |
| 5788 | PTPRC | 1 |
| 2313 | FLI1 | 3 |
| 10013 | HDAC6 | 2 |
| 11200 | CHEK2 | 1 |
| 51755 | CDK12 | 2 |
| 5596 | MAPK4 | 3 |
| 57472 | CNOT6 | 3 |
| 3604 | TNFRSF9 | 2 |
| 29998 | BICRA | 2 |
| 8295 | TRRAP | 6 |
| 1111 | CHEK1 | 2 |
| 10438 | C1D | 4 |
| 11122 | PTPRT | 1 |
| 6722 | SRF | 3 |
| 3456 | IFNB1 | 1 |
| 9024 | BRSK2 | 3 |
| 5159 | PDGFRB | 1 |
| 7173 | TPO | 5 |
| 10215 | OLIG2 | 3 |
| 4851 | NOTCH1 | 3 |
| 5605 | MAP2K2 | 3 |
| 51512 | GTSE1 | 3 |
| 139378 | ADGRG4 | 3 |
| 145264 | SERPINA12 | 3 |
| 55294 | FBXW7 | 3 |
| 10295 | BCKDK | 2 |
| 2033 | EP300 | 2 |
| 54567 | DLL4 | 3 |
| 8030 | CCDC6 | 3 |
| 5664 | PSEN2 | 3 |
| 9578 | CDC42BPB | 1 |
| 4361 | MRE11 | 2 |
| 83439 | TCF7L1 | 3 |
| 55728 | N4BP2 | 4 |
| 3227 | HOXC11 | 3 |
| 10006 | ABI1 | 2 |
| 6390 | SDHB | 6 |
| 102 | ADAM10 | 2 |
| 54477 | PLEKHA5 | 3 |
| 57670 | KIAA1549 | 4 |
| 440279 | UNC13C | 2 |
| 4301 | AFDN | 4 |
| 84033 | OBSCN | 5 |
| 5900 | RALGDS | 3 |
| 342977 | NANOS3 | 5 |
| 1540 | CYLD | 3 |
| 8600 | TNFSF11 | 3 |
| 7025 | NR2F1 | 2 |
| 3621 | ING1 | 3 |
| 23012 | STK38L | 3 |
| 3556 | IL1RAP | 3 |
| 8396 | PIP4K2B | 6 |
| 166614 | DCLK2 | 2 |
| 7416 | VDAC1 | 1 |
| 4005 | LMO2 | 3 |
| 22984 | PDCD11 | 2 |
| 6041 | RNASEL | 1 |
| 5468 | PPARG | 2 |
| 8313 | AXIN2 | 2 |
| 6091 | ROBO1 | 6 |
| 2042 | EPHA3 | 6 |
| 1050 | CEBPA | 1 |
| 2260 | FGFR1 | 3 |
| 23255 | MTCL1 | 4 |
| 730249 | ACOD1 | 4 |
| 80129 | CCDC170 | 3 |
| 10188 | TNK2 | 2 |
| 11169 | WDHD1 | 3 |
| 4216 | MAP3K4 | 5 |
| 2736 | GLI2 | 4 |
| 83990 | BRIP1 | 3 |
| 51804 | SIX4 | 2 |
| 9098 | USP6 | 2 |
| 6928 | HNF1B | 1 |
| 4194 | MDM4 | 3 |
| 7088 | TLE1 | 1 |
| 284217 | LAMA1 | 2 |
| 83931 | STK40 | 2 |
| 1143 | CHRNB4 | 3 |
| 55681 | SCYL2 | 5 |
| 4982 | TNFRSF11B | 3 |
| 23405 | DICER1 | 3 |
| 1992 | SERPINB1 | 1 |
| 399979 | SNX19 | 3 |
| 4752 | NEK3 | 3 |
| 22858 | ICK | 3 |
| 85443 | DCLK3 | 2 |
| 65266 | WNK4 | 2 |
| 287015 | TRIM42 | 3 |
| 57476 | GRAMD1B | 4 |
| 8643 | PTCH2 | 5 |
| 65217 | PCDH15 | 2 |
| 3916 | LAMP1 | 3 |
| 8395 | PIP5K1B | 2 |
| 6663 | SOX10 | 3 |
| 26750 | RPS6KC1 | 3 |
| 834 | CASP1 | 3 |
| 79971 | WLS | 3 |
| 9020 | MAP3K14 | 1 |
| 7486 | WRN | 2 |
| 29775 | CARD10 | 3 |
| 23191 | CYFIP1 | 3 |
| 783 | CACNB2 | 5 |
| 6416 | MAP2K4 | 3 |
| 92 | ACVR2A | 1 |
| 29760 | BLNK | 3 |
| 8714 | ABCC3 | 4 |
| 5286 | PIK3C2A | 2 |
| 25989 | ULK3 | 1 |
| 1973 | EIF4A1 | 3 |
| 6793 | STK10 | 4 |
| 50488 | MINK1 | 2 |
| 6464 | SHC1 | 3 |
| 7166 | TPH1 | 8 |
| 9472 | AKAP6 | 2 |
| 54437 | SEMA5B | 3 |
| 8515 | ITGA10 | 2 |
| 6917 | TCEA1 | 3 |
| 3667 | IRS1 | 2 |
| 80243 | PREX2 | 1 |
| 472 | ATM | 5 |
| 8945 | BTRC | 3 |
| 5165 | PDK3 | 4 |
| 139285 | AMER1 | 3 |
| 4087 | SMAD2 | 2 |
| 9096 | TBX18 | 3 |
| 9564 | BCAR1 | 3 |
| 4058 | LTK | 2 |
| 6792 | CDKL5 | 1 |
| 1123 | CHN1 | 1 |
| 1496 | CTNNA2 | 7 |
| 7010 | TEK | 3 |
| 7533 | YWHAH | 3 |
| 5289 | PIK3C3 | 1 |
| 5450 | POU2AF1 | 1 |
| 2272 | FHIT | 5 |
| 7867 | MAPKAPK3 | 1 |
| 2066 | ERBB4 | 6 |
| 904 | CCNT1 | 3 |
| 10290 | SPEG | 1 |
| 79442 | LRRC2 | 1 |
| 10413 | YAP1 | 3 |
| 1029 | CDKN2A | 1 |
| 7184 | HSP90B1 | 3 |
| 10062 | NR1H3 | 3 |
| 5108 | PCM1 | 4 |
| 23048 | FNBP1 | 5 |
| 157753 | TMEM74 | 1 |
| 57523 | NYNRIN | 5 |
| 83694 | RPS6KL1 | 3 |
| 1910 | EDNRB | 6 |
| 657 | BMPR1A | 3 |
| 5336 | PLCG2 | 1 |
| 9874 | TLK1 | 3 |
| 5834 | PYGB | 1 |
| 58508 | KMT2C | 4 |
| 6092 | ROBO2 | 1 |
| 7704 | ZBTB16 | 3 |
| 4088 | SMAD3 | 3 |
| 27086 | FOXP1 | 8 |
| 4173 | MCM4 | 4 |
| 4855 | NOTCH4 | 3 |
| 57194 | ATP10A | 3 |
| 4857 | NOVA1 | 3 |
| 25836 | NIPBL | 4 |
| 8218 | CLTCL1 | 4 |
| 5910 | RAP1GDS1 | 6 |
| 3791 | KDR | 1 |
| 10114 | HIPK3 | 5 |
| 4292 | MLH1 | 2 |
| 114788 | CSMD3 | 6 |
| 2263 | FGFR2 | 2 |
| 4086 | SMAD1 | 1 |
| 9639 | ARHGEF10 | 6 |
| 7249 | TSC2 | 2 |
| 1019 | CDK4 | 1 |
| 7409 | VAV1 | 3 |
| 11213 | IRAK3 | 6 |
| 9967 | THRAP3 | 3 |
| 55034 | MOCOS | 3 |
| 23043 | TNIK | 3 |
| 55437 | STRADB | 3 |
| 2309 | FOXO3 | 2 |
| 7038 | TG | 2 |
| 3572 | IL6ST | 3 |
| 5077 | PAX3 | 7 |
| 9965 | FGF19 | 1 |
| 6197 | RPS6KA3 | 4 |
| 55589 | BMP2K | 3 |
| 65125 | WNK1 | 4 |
| 136332 | LRGUK | 10 |
| 4436 | MSH2 | 4 |
| 1441 | CSF3R | 3 |
| 7175 | TPR | 4 |
| 5871 | MAP4K2 | 4 |
| 80205 | CHD9 | 3 |
| 57578 | UNC79 | 2 |
| 4026 | LPP | 3 |
| 8997 | KALRN | 6 |
| 4437 | MSH3 | 1 |
| 2071 | ERCC3 | 3 |
| 23269 | MGA | 4 |
| 7994 | KAT6A | 3 |
| 57551 | TAOK1 | 3 |
| 2175 | FANCA | 2 |
| 4089 | SMAD4 | 3 |
| 170692 | ADAMTS18 | 3 |
| 6654 | SOS1 | 6 |
| 672 | BRCA1 | 5 |
| 2668 | GDNF | 6 |
| 11168 | PSIP1 | 3 |
| 7204 | TRIO | 4 |
| 10733 | PLK4 | 3 |
| 23373 | CRTC1 | 2 |
| 546 | ATRX | 1 |
| 51366 | UBR5 | 6 |
| 3426 | CFI | 2 |
| 3417 | IDH1 | 3 |
| 23678 | SGK3 | 4 |
| 5606 | MAP2K3 | 3 |
| 5297 | PI4KA | 5 |
| 54756 | IL17RD | 6 |
| 1978 | EIF4EBP1 | 1 |
| 10535 | RNASEH2A | 1 |
| 10769 | PLK2 | 2 |
| 56997 | COQ8A | 3 |
| 286133 | SCARA5 | 3 |
| 4214 | MAP3K1 | 4 |
| 3702 | ITK | 5 |
| 9972 | NUP153 | 2 |
| 3239 | HOXD13 | 7 |
| 5290 | PIK3CA | 7 |
| 3562 | IL3 | 3 |
| 92335 | STRADA | 6 |
| 3720 | JARID2 | 5 |
| 1514 | CTSL | 2 |
| 5034 | P4HB | 3 |
| 1000 | CDH2 | 2 |
| 1687 | GSDME | 3 |
| 8202 | NCOA3 | 1 |
| 4293 | MAP3K9 | 2 |
| 26524 | LATS2 | 3 |
| 5045 | FURIN | 3 |
| 85366 | MYLK2 | 6 |
| 2318 | FLNC | 5 |
| 64919 | BCL11B | 4 |
| 2030 | SLC29A1 | 3 |
| 675 | BRCA2 | 6 |
| 3458 | IFNG | 3 |
| 26166 | RGS22 | 5 |
| 607 | BCL9 | 3 |
| 7075 | TIE1 | 4 |
| 640 | BLK | 5 |
| 841 | CASP8 | 1 |
| 2735 | GLI1 | 1 |
| 3065 | HDAC1 | 3 |
| 4609 | MYC | 3 |
| 64333 | ARHGAP9 | 2 |
| 11064 | CNTRL | 2 |
| 90956 | ADCK2 | 3 |
| 2624 | GATA2 | 3 |
| 5789 | PTPRD | 2 |
| 8013 | NR4A3 | 3 |
| 10461 | MERTK | 3 |
| 6885 | MAP3K7 | 3 |
| 26278 | SACS | 4 |
| 5462 | POU5F1B | 1 |
| 1440 | CSF3 | 3 |
| 51701 | NLK | 2 |
| 6446 | SGK1 | 3 |
| 79759 | ZNF668 | 1 |
| 3553 | IL1B | 3 |
| 833 | CARS | 6 |
| 5747 | PTK2 | 2 |
| 7443 | VRK1 | 2 |
| 7917 | BAG6 | 2 |
| 375056 | MIA3 | 3 |
| 10000 | AKT3 | 3 |
| 91754 | NEK9 | 3 |
| 93627 | TBCK | 2 |
| 137872 | ADHFE1 | 3 |
| 27330 | RPS6KA6 | 3 |
| 203102 | ADAM32 | 6 |
| 7153 | TOP2A | 3 |
| 57082 | KNL1 | 4 |
| 1981 | EIF4G1 | 3 |
| 1213 | CLTC | 1 |
| 1769 | DNAH8 | 1 |
| 22976 | PAXIP1 | 2 |
| 3315 | HSPB1 | 1 |
| 23532 | PRAME | 5 |
| 4863 | NPAT | 5 |
| 780 | DDR1 | 2 |
| 83452 | RAB33B | 3 |
| 57538 | ALPK3 | 1 |
| 8924 | HERC2 | 1 |
| 120892 | LRRK2 | 7 |
| 89795 | NAV3 | 1 |
| 11126 | CD160 | 4 |
| 79184 | BRCC3 | 2 |
| 867 | CBL | 3 |
| 6095 | RORA | 7 |
| 146057 | TTBK2 | 3 |
| 84441 | MAML2 | 3 |
| 5205 | ATP8B1 | 4 |
| 7468 | NSD2 | 3 |
| 8029 | CUBN | 5 |
| 8626 | TP63 | 2 |
| 9113 | LATS1 | 1 |
| 460 | ASTN1 | 2 |
| 8178 | ELL | 3 |
| 7849 | PAX8 | 1 |
| 9321 | TRIP11 | 5 |
| 9451 | EIF2AK3 | 2 |
| 8491 | MAP4K3 | 3 |
| 4853 | NOTCH2 | 1 |
| 162968 | ZNF497 | 3 |
| 8621 | CDK13 | 3 |
| 23049 | SMG1 | 2 |
| 10010 | TANK | 2 |
| 8312 | AXIN1 | 2 |
| 55521 | TRIM36 | 5 |
| 10752 | CHL1 | 2 |
| 5728 | PTEN | 3 |
| 5595 | MAPK3 | 3 |
| 1869 | E2F1 | 4 |
| 4914 | NTRK1 | 6 |
| 22883 | CLSTN1 | 3 |
| 667 | DST | 4 |
| 115701 | ALPK2 | 4 |
| 4004 | LMO1 | 3 |
| 3554 | IL1R1 | 2 |
| 2897 | GRIK1 | 3 |
| 6770 | STAR | 3 |
| 2188 | FANCF | 3 |
| 2324 | FLT4 | 2 |
| 658 | BMPR1B | 3 |
| 5896 | RAG1 | 3 |
| 1676 | DFFA | 3 |
| 2870 | GRK6 | 3 |
| 8301 | PICALM | 3 |
| 7273 | TTN | 3 |
| 1018 | CDK3 | 4 |
| 79834 | PEAK1 | 7 |
| 7465 | WEE1 | 3 |
| 23332 | CLASP1 | 3 |
| 7059 | THBS3 | 2 |
| 7454 | WAS | 7 |
| 23389 | MED13L | 2 |
| 54904 | NSD3 | 3 |
| 387 | RHOA | 5 |
| 79012 | CAMKV | 2 |
| 2046 | EPHA8 | 1 |
| 1027 | CDKN1B | 1 |
| 8821 | INPP4B | 3 |
| 221895 | JAZF1 | 2 |
| 5532 | PPP3CB | 2 |
| 22843 | PPM1E | 1 |
| 286151 | FBXO43 | 5 |
| 26686 | OR4E2 | 3 |
| 1662 | DDX10 | 2 |
| 344905 | ATP13A5 | 2 |
| 51151 | SLC45A2 | 5 |
| 10076 | PTPRU | 2 |
| 558 | AXL | 3 |
| 7248 | TSC1 | 4 |
| 4619 | MYH1 | 4 |
| 2932 | GSK3B | 4 |
| 2869 | GRK5 | 2 |
| 5581 | PRKCE | 3 |
| 5923 | RASGRF1 | 6 |
| 317 | APAF1 | 2 |
| 10111 | RAD50 | 3 |
| 100124696 | TEC | 6 |
| 9223 | MAGI1 | 3 |
| 55289 | ACOXL | 4 |
| 9659 | PDE4DIP | 3 |
| 9201 | DCLK1 | 2 |
| 4000 | LMNA | 3 |
| 54101 | RIPK4 | 2 |
| 3557 | IL1RN | 1 |
| 131890 | GRK7 | 2 |
| 5927 | KDM5A | 5 |
| 1385 | CREB1 | 3 |
| 5587 | PRKD1 | 3 |
| 55007 | FAM118A | 2 |
| 900 | CCNG1 | 3 |
| 2321 | FLT1 | 2 |
| 57448 | BIRC6 | 3 |
| 2131 | EXT1 | 6 |
| 8317 | CDC7 | 2 |
| 3717 | JAK2 | 3 |
| 23139 | MAST2 | 3 |
| 2157 | F8 | 3 |
| 7227 | TRPS1 | 3 |
| 5506 | PPP1R3A | 3 |
| 79837 | PIP4K2C | 1 |
| 3709 | ITPR2 | 3 |
| 57147 | SCYL3 | 2 |
| 6778 | STAT6 | 3 |
| 4221 | MEN1 | 3 |
| 8899 | PRPF4B | 3 |
| 4067 | LYN | 5 |
| 1030 | CDKN2B | 1 |
| 65267 | WNK3 | 3 |
| 3984 | LIMK1 | 4 |
| 3552 | IL1A | 1 |
| 80216 | ALPK1 | 3 |
| 5932 | RBBP8 | 4 |
| 3977 | LIFR | 3 |
| 7112 | TMPO | 1 |
| 3656 | IRAK2 | 3 |
| 4330 | MN1 | 2 |
| 170685 | NUDT10 | 1 |
| 182 | JAG1 | 6 |
| 7913 | DEK | 3 |
| 8536 | CAMK1 | 3 |
| 2122 | MECOM | 3 |
| 5087 | PBX1 | 1 |
| 3815 | KIT | 1 |
| 9894 | TELO2 | 1 |
| 5925 | RB1 | 1 |
| 4217 | MAP3K5 | 2 |
| 1515 | CTSV | 3 |
| 4893 | NRAS | 1 |
| 1209 | CLPTM1 | 2 |
| 2074 | ERCC6 | 2 |
| 5324 | PLAG1 | 3 |
| 8661 | EIF3A | 6 |
| 3691 | ITGB4 | 2 |
| 10420 | TESK2 | 3 |
| 7403 | KDM6A | 6 |
| 2534 | FYN | 3 |
| 4638 | MYLK | 4 |
| 7040 | TGFB1 | 4 |
| 30849 | PIK3R4 | 2 |
| 3488 | IGFBP5 | 3 |
| 23092 | ARHGAP26 | 3 |
| 4915 | NTRK2 | 4 |
| 4299 | AFF1 | 2 |
| 2651 | GCNT2 | 2 |
| 11086 | ADAM29 | 4 |
| 374 | AREG | 2 |
| 2261 | FGFR3 | 2 |
| 23072 | HECW1 | 3 |
| 55422 | ZNF331 | 4 |
| 1013 | CDH15 | 3 |
| 8321 | FZD1 | 3 |
| 595 | CCND1 | 1 |
| 4763 | NF1 | 1 |
| 5260 | PHKG1 | 1 |
| 55791 | LRIF1 | 4 |
| 63893 | UBE2O | 4 |
| 6886 | TAL1 | 3 |
| 10891 | PPARGC1A | 1 |
| 440270 | GOLGA8B | 3 |
| 4286 | MITF | 3 |
| 94 | ACVRL1 | 1 |
| 2044 | EPHA5 | 5 |
| 4593 | MUSK | 2 |
| 4629 | MYH11 | 3 |
| 23683 | PRKD3 | 3 |
| 10048 | RANBP9 | 4 |
| 699 | BUB1 | 1 |
| 6868 | ADAM17 | 3 |
| 23112 | TNRC6B | 1 |
| 27255 | CNTN6 | 2 |
| 1803 | DPP4 | 1 |
| 83732 | RIOK1 | 3 |
| 29110 | TBK1 | 1 |
| 1499 | CTNNB1 | 3 |
| 2444 | FRK | 5 |
| 56155 | TEX14 | 3 |
| 2892 | GRIA3 | 8 |
| 1436 | CSF1R | 3 |
| 167359 | NIM1K | 2 |
| 4486 | MST1R | 3 |
| 2904 | GRIN2B | 2 |
| 1488 | CTBP2 | 4 |
Gene in drug-gene network: Network Plot
Models in Isoevodiamine
CLASSFICATION
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