POU2AF1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| POU class 2 associating factor 1 | MIM:601206 | Ensembl:ENSG00000110777 | HGNC:HGNC:9211 | PA33535 | 11q23.1 |
Gene Categories:
TRANSCRIPTION FACTOR COMPLEXGO terms in POU2AF1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IDA | GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | IMP | GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding |
| MF | IMP | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding |
| MF | TAS | GO:0003712 | transcription coregulator activity |
| MF | IMP | GO:0003713 | transcription coactivator activity |
| MF | IPI | GO:0005515 | protein binding |
| CC | IDA | GO:0090575 | RNA polymerase II transcription factor complex |
| CC | IMP | GO:0090575 | RNA polymerase II transcription factor complex |
| BP | TAS | GO:0006366 | transcription by RNA polymerase II |
| BP | TAS | GO:0006959 | humoral immune response |
| BP | IGI | GO:0045944 | positive regulation of transcription by RNA polymerase II |
Gene expression in normal tissue: POU2AF1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in POU2AF1
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD151 | CHM-1 | 1 |
| iGMDRD126 | Tipifarnib | 7 |
| iGMDRD425 | ERASTIN | 2 |
| iGMDRD866 | BRD1812 | 5 |
| iGMDRD546 | BMS-754807 | 2 |
| iGMDRD670 | ML 210 | 5 |
| iGMDRD781 | Sirolimus | 5 |
| iGMDRD107 | Valdecoxib | 5 |
| iGMDRD2 | PK-11195 | 4 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD679 | Bistramide A | 1 |
| iGMDRD513 | BML-259 | 3 |
| iGMDRD187 | BRD9876 | 2 |
| iGMDRD730 | Kahalalide F | 2 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD888 | Compound 44 | 10 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD23 | Gossypol | 4 |
| iGMDRD356 | PNU-74654 | 4 |
| iGMDRD405 | PIK-75 | 3 |
| iGMDRD341 | Triacsin c | 5 |
| iGMDRD219 | Bax channel blocker | 1 |
| iGMDRD698 | Neratinib | 1 |
| iGMDRD123 | Isoevodiamine | 1 |
| iGMDRD137 | Indisulam | 4 |
| iGMDRD202 | Curcumin | 6 |
| iGMDRD103 | SN-38 | 4 |
| iGMDRD5 | Tyrphostin AG 1478 | 3 |
| iGMDRD221 | Tamoxifen | 8 |
| iGMDRD105 | Triptolide | 5 |
| iGMDRD213 | SMR000068650 | 5 |
| iGMDRD286 | Nsc 632839 | 6 |
| iGMDRD871 | BRD6368 | 1 |
| iGMDRD366 | PI-103 | 5 |
| iGMDRD147 | Prima-1 | 2 |
| iGMDRD554 | CHEMBL1434137 | 4 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD579 | PF750 | 8 |
| iGMDRD772 | BRD4770 | 8 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD201 | SKI II | 5 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD163 | all trans Retinoic Acid | 4 |
| iGMDRD193 | Fqi1 | 1 |
| iGMDRD297 | Austocystin D | 3 |
| iGMDRD634 | SCHEMBL2608041 | 4 |
| iGMDRD870 | BRD63610 | 3 |
| iGMDRD309 | 17AAG | 1 |
| iGMDRD441 | TW 37 | 4 |
| iGMDRD318 | PAC-1 | 1 |
| iGMDRD885 | Compound 110 | 1 |
| iGMDRD887 | Compound 23 citrate | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD640 | CAY10618 | 3 |
| iGMDRD690 | PRIMA-1MET | 7 |
| iGMDRD268 | Cerulenin | 5 |
| iGMDRD486 | Tosedostat | 4 |
| iGMDRD307 | Manumycin A | 2 |
| iGMDRD84 | Lovastatin acid | 2 |
| iGMDRD148 | Pifithrin-mu | 8 |
| iGMDRD701 | NVP-AUY922 | 1 |
| iGMDRD351 | GW843682X | 4 |
| iGMDRD211 | (1S,3R)-RSL3 | 4 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 1 |
| iGMDRD6 | AM-580 | 7 |
| iGMDRD267 | Oligomycin A | 3 |
| iGMDRD481 | Dactolisib | 2 |
| iGMDRD882 | CIL41 | 2 |
| iGMDRD872 | BRD7137 | 2 |
| iGMDRD414 | MST-312 | 1 |
| iGMDRD269 | Purmorphamine | 4 |
| iGMDRD505 | Pevonedistat | 2 |
| iGMDRD300 | Tozasertib | 5 |
| iGMDRD82 | Quiflapon | 5 |
| iGMDRD353 | PD0325901 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in POU2AF1
CLASSFICATION
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