iGMDRD147
| Standard Name | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|
| Prima-1 | 322968 | Alone | Small Molecule |
Drug Targets:
TP53Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 6664 | SOX11 | 3 |
| 3725 | JUN | 1 |
| 10903 | MTMR11 | 1 |
| 79848 | CSPP1 | 2 |
| 8444 | DYRK3 | 2 |
| 132 | ADK | 3 |
| 3383 | ICAM1 | 1 |
| 7161 | TP73 | 1 |
| 5546 | PRCC | 1 |
| 2200 | FBN1 | 1 |
| 51765 | STK26 | 3 |
| 9706 | ULK2 | 3 |
| 93 | ACVR2B | 1 |
| 4750 | NEK1 | 3 |
| 80070 | ADAMTS20 | 1 |
| 8266 | UBL4A | 2 |
| 3939 | LDHA | 1 |
| 51129 | ANGPTL4 | 3 |
| 6938 | TCF12 | 2 |
| 7850 | IL1R2 | 3 |
| 9475 | ROCK2 | 2 |
| 29888 | STRN4 | 1 |
| 7942 | TFEB | 3 |
| 6657 | SOX2 | 3 |
| 5079 | PAX5 | 3 |
| 4170 | MCL1 | 1 |
| 55781 | RIOK2 | 3 |
| 55534 | MAML3 | 3 |
| 4092 | SMAD7 | 1 |
| 2623 | GATA1 | 3 |
| 1387 | CREBBP | 6 |
| 5756 | TWF1 | 1 |
| 2043 | EPHA4 | 2 |
| 5788 | PTPRC | 3 |
| 5579 | PRKCB | 4 |
| 8295 | TRRAP | 3 |
| 5159 | PDGFRB | 3 |
| 7373 | COL14A1 | 2 |
| 54567 | DLL4 | 2 |
| 4001 | LMNB1 | 1 |
| 641 | BLM | 2 |
| 23522 | KAT6B | 4 |
| 4610 | MYCL | 6 |
| 816 | CAMK2B | 2 |
| 55819 | RNF130 | 3 |
| 122011 | CSNK1A1L | 2 |
| 8549 | LGR5 | 1 |
| 22806 | IKZF3 | 3 |
| 166614 | DCLK2 | 1 |
| 3645 | INSRR | 1 |
| 6733 | SRPK2 | 2 |
| 5984 | RFC4 | 3 |
| 29904 | EEF2K | 3 |
| 83931 | STK40 | 2 |
| 1277 | COL1A1 | 1 |
| 171019 | ADAMTS19 | 1 |
| 57476 | GRAMD1B | 1 |
| 23191 | CYFIP1 | 3 |
| 5127 | CDK16 | 1 |
| 57510 | XPO5 | 3 |
| 6709 | SPTAN1 | 2 |
| 8215 | DVL1P1 | 1 |
| 50488 | MINK1 | 4 |
| 2778 | GNAS | 1 |
| 6917 | TCEA1 | 3 |
| 139285 | AMER1 | 2 |
| 5924 | RASGRF2 | 2 |
| 4087 | SMAD2 | 2 |
| 54986 | ULK4 | 1 |
| 1496 | CTNNA2 | 1 |
| 5450 | POU2AF1 | 2 |
| 23152 | CIC | 1 |
| 2272 | FHIT | 4 |
| 5863 | RGL2 | 3 |
| 9794 | MAML1 | 2 |
| 5129 | CDK18 | 3 |
| 27436 | EML4 | 2 |
| 157753 | TMEM74 | 2 |
| 8576 | STK16 | 3 |
| 7157 | TP53 | 1 |
| 4173 | MCM4 | 2 |
| 6794 | STK11 | 2 |
| 25836 | NIPBL | 3 |
| 7869 | SEMA3B | 1 |
| 8218 | CLTCL1 | 3 |
| 3791 | KDR | 1 |
| 7249 | TSC2 | 2 |
| 65243 | ZFP69B | 5 |
| 344387 | CDKL4 | 3 |
| 863 | CBFA2T3 | 3 |
| 10516 | FBLN5 | 1 |
| 369 | ARAF | 2 |
| 652 | BMP4 | 1 |
| 1656 | DDX6 | 1 |
| 8115 | TCL1A | 1 |
| 8997 | KALRN | 1 |
| 4437 | MSH3 | 5 |
| 57551 | TAOK1 | 1 |
| 4089 | SMAD4 | 1 |
| 170692 | ADAMTS18 | 2 |
| 54658 | UGT1A1 | 1 |
| 1616 | DAXX | 3 |
| 2737 | GLI3 | 1 |
| 78989 | COLEC11 | 2 |
| 23373 | CRTC1 | 1 |
| 5727 | PTCH1 | 1 |
| 9448 | MAP4K4 | 1 |
| 285220 | EPHA6 | 2 |
| 7786 | MAP3K12 | 1 |
| 10769 | PLK2 | 2 |
| 5578 | PRKCA | 2 |
| 440275 | EIF2AK4 | 1 |
| 5290 | PIK3CA | 3 |
| 1687 | GSDME | 2 |
| 4293 | MAP3K9 | 2 |
| 90 | ACVR1 | 2 |
| 5366 | PMAIP1 | 1 |
| 7043 | TGFB3 | 3 |
| 10565 | ARFGEF1 | 2 |
| 5530 | PPP3CA | 3 |
| 28958 | COA3 | 1 |
| 1956 | EGFR | 2 |
| 4609 | MYC | 3 |
| 64333 | ARHGAP9 | 1 |
| 90956 | ADCK2 | 3 |
| 5462 | POU5F1B | 1 |
| 2189 | FANCG | 1 |
| 3635 | INPP5D | 2 |
| 1653 | DDX1 | 1 |
| 375056 | MIA3 | 2 |
| 1544 | CYP1A2 | 3 |
| 10000 | AKT3 | 3 |
| 93627 | TBCK | 2 |
| 6872 | TAF1 | 2 |
| 673 | BRAF | 5 |
| 4790 | NFKB1 | 3 |
| 1769 | DNAH8 | 1 |
| 780 | DDR1 | 2 |
| 8924 | HERC2 | 2 |
| 2078 | ERG | 3 |
| 7027 | TFDP1 | 3 |
| 867 | CBL | 4 |
| 7301 | TYRO3 | 1 |
| 93273 | LEMD1 | 3 |
| 5294 | PIK3CG | 6 |
| 10253 | SPRY2 | 3 |
| 55290 | BRF2 | 3 |
| 266747 | RGL4 | 1 |
| 8621 | CDK13 | 2 |
| 5563 | PRKAA2 | 4 |
| 7030 | TFE3 | 3 |
| 8888 | MCM3AP | 2 |
| 7155 | TOP2B | 1 |
| 80124 | VCPIP1 | 3 |
| 667 | DST | 2 |
| 140803 | TRPM6 | 3 |
| 1950 | EGF | 1 |
| 7036 | TFR2 | 3 |
| 55359 | STYK1 | 3 |
| 53904 | MYO3A | 3 |
| 9372 | ZFYVE9 | 4 |
| 128869 | PIGU | 1 |
| 10595 | ERN2 | 2 |
| 2072 | ERCC4 | 1 |
| 5588 | PRKCQ | 1 |
| 51151 | SLC45A2 | 6 |
| 10076 | PTPRU | 4 |
| 332 | BIRC5 | 1 |
| 2041 | EPHA1 | 1 |
| 2317 | FLNB | 2 |
| 9021 | SOCS3 | 2 |
| 8031 | NCOA4 | 3 |
| 1789 | DNMT3B | 1 |
| 140913 | PPIAP10 | 1 |
| 55289 | ACOXL | 2 |
| 6093 | ROCK1 | 3 |
| 5587 | PRKD1 | 1 |
| 1719 | DHFR | 5 |
| 3717 | JAK2 | 2 |
| 22982 | DIP2C | 1 |
| 6777 | STAT5B | 1 |
| 3552 | IL1A | 2 |
| 80216 | ALPK1 | 3 |
| 444 | ASPH | 1 |
| 11076 | TPPP | 1 |
| 7913 | DEK | 1 |
| 51167 | CYB5R4 | 1 |
| 2074 | ERCC6 | 2 |
| 7403 | KDM6A | 3 |
| 2308 | FOXO1 | 1 |
| 8841 | HDAC3 | 1 |
| 255239 | ANKK1 | 3 |
| 30849 | PIK3R4 | 1 |
| 55959 | SULF2 | 1 |
| 9878 | TOX4 | 3 |
| 2011 | MARK2 | 3 |
| 23092 | ARHGAP26 | 1 |
| 23072 | HECW1 | 3 |
| 139604 | MAGEB16 | 1 |
| 84197 | POMK | 1 |
| 581 | BAX | 3 |
| 595 | CCND1 | 3 |
| 10891 | PPARGC1A | 2 |
| 23683 | PRKD3 | 3 |
| 4780 | NFE2L2 | 1 |
| 6868 | ADAM17 | 1 |
| 2444 | FRK | 1 |
| 1436 | CSF1R | 3 |
| 4916 | NTRK3 | 3 |
| 5685 | PSMA4 | 3 |
Gene in drug-gene network: Network Plot
Models in Prima-1
CLASSFICATION
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