RIOK2
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| RIO kinase 2 | MIM:617754 | Ensembl:ENSG00000058729 | HGNC:HGNC:18999 | PA134885533 | 5q15 |
GO terms in RIOK2
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IBA | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IMP | GO:0005737 | cytoplasm |
| CC | IBA | GO:0005829 | cytosol |
| CC | TAS | GO:0005829 | cytosol |
| CC | IBA | GO:0030688 | preribosome, small subunit precursor |
| CC | IDA | GO:0030688 | preribosome, small subunit precursor |
| BP | IEA | GO:0007049 | cell cycle |
| BP | IMP | GO:0030071 | regulation of mitotic metaphase/anaphase transition |
| BP | IBA | GO:0030490 | maturation of SSU-rRNA |
| BP | IMP | GO:0030490 | maturation of SSU-rRNA |
| BP | IMP | GO:0042274 | ribosomal small subunit biogenesis |
| BP | IMP | GO:0046777 | protein autophosphorylation |
| BP | IMP | GO:2000208 | positive regulation of ribosomal small subunit export from nucleus |
| BP | IDA | GO:2000234 | positive regulation of rRNA processing |
| MF | IBA | GO:0004672 | protein kinase activity |
| MF | IEA | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0046872 | metal ion binding |
Gene expression in normal tissue: RIOK2
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in RIOK2
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa03008 | Ribosome biogenesis in eukaryotes - Homo sapiens (human) |
| reactome | R-HSA-6791226 | Major pathway of rRNA processing in the nucleolus and cytosol |
| reactome | R-HSA-72312 | rRNA processing |
| reactome | R-HSA-8868773 | rRNA processing in the nucleus and cytosol |
| reactome | R-HSA-8953854 | Metabolism of RNA |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD137 | Indisulam | 3 |
| iGMDRD289 | Parthenolide | 3 |
| iGMDRD105 | Triptolide | 3 |
| iGMDRD52 | Rotenone | 6 |
| iGMDRD188 | Piperlongumine | 3 |
| iGMDRD286 | Nsc 632839 | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD60 | Quinoclamine | 3 |
| iGMDRD147 | Prima-1 | 3 |
| iGMDRD268 | Cerulenin | 3 |
| iGMDRD330 | BRD4132 | 3 |
| iGMDRD599 | Salermide | 3 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD150 | RITA | 1 |
| iGMDRD144 | NSC95397 | 3 |
| iGMDRD523 | Cyanoquinoline, 11 | 3 |
| iGMDRD494 | Neopeltolide | 1 |
| iGMDRD652 | UNC0638 | 3 |
| iGMDRD85 | Ursolic acid | 1 |
| iGMDRD466 | Chaetocin | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in RIOK2
CLASSFICATION
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