SEARCH

HOME / SEARCH / Neopeltolide

iGMDRD494

Canonical SMILES: CCCC1CC(CC(CC2CC(CC(O2)CC(=O)O1)OC(=O)C=CCCC3=COC(=N3)C=CCNC(=O)OC)C)OC

InChI: InChI=1S/C31H46N2O9/c1-5-9-23-16-24(37-3)14-21(2)15-25-17-26(18-27(40-25)19-30(35)41-23)42-29(34)12-7-6-10-22-20-39-28(33-22)11-8-13-32-31(36)38-4/h7-8,11-12,20-21,23-27H,5-6,9-10,13-19H2,1-4H3,(H,32,36)/b11-8-,12-7-/t21-,23+,24+,25+,26+,27+/m0/s1

InChI Key: YRSJLYCTJWNTMF-NRBUTUAXSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Neopeltolide	16115400	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
3696	ITGB8	3
1147	CHUK	2
27125	AFF4	2
4854	NOTCH3	4
8999	CDKL2	1
7074	TIAM1	2
10903	MTMR11	3
79848	CSPP1	1
7837	PXDN	3
8444	DYRK3	2
7421	VDR	3
7161	TP73	3
4926	NUMA1	2
11183	MAP4K5	1
4627	MYH9	2
55872	PBK	3
4303	FOXO4	2
150465	TTL	3
1588	CYP19A1	2
9706	ULK2	1
347365	ITIH6	3
51347	TAOK3	3
2100	ESR2	3
8573	CASK	2
5934	RBL2	2
53616	ADAM22	5
2475	MTOR	2
6597	SMARCA4	1
3551	IKBKB	3
2176	FANCC	2
11160	ERLIN2	2
5241	PGR	3
5133	PDCD1	2
390502	SERPINA2	2
5754	PTK7	2
64783	RBM15	2
51684	SUFU	1
10863	ADAM28	2
1607	DGKB	5
9641	IKBKE	3
55781	RIOK2	1
23310	NCAPD3	2
5298	PI4KB	1
341676	NEK5	3
7048	TGFBR2	2
2249	FGF4	2
51199	NIN	2
577	ADGRB3	2
2043	EPHA4	1
5788	PTPRC	2
5579	PRKCB	1
1602	DACH1	2
10178	TENM1	2
9699	RIMS2	3
9411	ARHGAP29	4
5074	PAWR	3
8295	TRRAP	1
26576	SRPK3	3
2977	GUCY1A2	1
11122	PTPRT	4
23617	TSSK2	5
7373	COL14A1	2
5166	PDK4	2
10215	OLIG2	3
5465	PPARA	3
5314	PKHD1	2
5605	MAP2K2	3
7158	TP53BP1	2
2033	EP300	5
6927	HNF1A	2
8030	CCDC6	3
641	BLM	1
4595	MUTYH	3
23522	KAT6B	6
10818	FRS2	1
102	ADAM10	2
440279	UNC13C	2
4610	MYCL	2
3976	LIF	3
4301	AFDN	3
816	CAMK2B	3
84033	OBSCN	3
342977	NANOS3	1
256646	NUTM1	3
1540	CYLD	2
8767	RIPK2	2
23012	STK38L	3
646643	SBK2	3
4478	MSN	4
6256	RXRA	4
3556	IL1RAP	2
5613	PRKX	2
26353	HSPB8	3
4005	LMO2	3
200576	PIKFYVE	3
8313	AXIN2	1
116986	AGAP2	4
51343	FZR1	5
114548	NLRP3	2
80129	CCDC170	3
10188	TNK2	2
9636	ISG15	3
10217	CTDSPL	1
2908	NR3C1	3
83990	BRIP1	1
7088	TLE1	2
284217	LAMA1	4
1143	CHRNB4	2
4982	TNFRSF11B	1
7016	TESK1	3
399979	SNX19	3
171019	ADAMTS19	3
94103	ORMDL3	2
6850	SYK	2
287015	TRIM42	3
65217	PCDH15	3
55361	PI4K2A	6
1456	CSNK1G3	5
6416	MAP2K4	6
9759	HDAC4	1
92	ACVR2A	2
1452	CSNK1A1	2
6709	SPTAN1	4
219970	GLYATL2	3
6793	STK10	7
5591	PRKDC	6
79705	LRRK1	3
5568	PRKACG	2
659	BMPR2	2
6098	ROS1	1
9472	AKAP6	2
2778	GNAS	1
3685	ITGAV	5
3667	IRS1	2
472	ATM	5
8945	BTRC	4
139285	AMER1	3
8148	TAF15	2
53942	CNTN5	5
5924	RASGRF2	3
4058	LTK	4
6792	CDKL5	3
7010	TEK	1
5289	PIK3C3	2
898	CCNE1	2
23152	CIC	3
2272	FHIT	2
7681	MKRN3	3
5863	RGL2	2
9319	TRIP13	1
2201	FBN2	3
1029	CDKN2A	1
7184	HSP90B1	2
5108	PCM1	3
139728	PNCK	6
27436	EML4	3
83694	RPS6KL1	3
9874	TLK1	3
27347	STK39	2
58508	KMT2C	2
7157	TP53	1
6092	ROBO2	3
4602	MYB	2
79058	ASPSCR1	3
25836	NIPBL	1
397	ARHGDIB	6
4292	MLH1	3
6184	RPN1	3
2133	EXT3	3
7249	TSC2	1
65243	ZFP69B	2
64386	MMP25	3
51086	TNNI3K	2
7038	TG	5
6197	RPS6KA3	4
57188	ADAMTSL3	1
65125	WNK1	1
50945	TBX22	3
652	BMP4	3
1656	DDX6	2
7175	TPR	2
80205	CHD9	3
2000	ELF4	4
84181	CHD6	2
57578	UNC79	4
4026	LPP	1
8997	KALRN	2
7994	KAT6A	4
6280	S100A9	3
5371	PML	2
23469	PHF3	2
4089	SMAD4	1
7204	TRIO	2
256536	TCERG1L	2
9252	RPS6KA5	2
10733	PLK4	3
23373	CRTC1	1
285220	EPHA6	1
5297	PI4KA	1
10926	DBF4	3
10535	RNASEH2A	3
64840	PORCN	1
57144	PAK5	2
5578	PRKCA	3
4214	MAP3K1	1
440275	EIF2AK4	3
8731	RNMT	3
50615	IL21R	2
3720	JARID2	2
5034	P4HB	2
4145	MATK	3
7043	TGFB3	3
2318	FLNC	1
10565	ARFGEF1	4
64919	BCL11B	4
2030	SLC29A1	3
675	BRCA2	2
607	BCL9	2
7075	TIE1	3
8445	DYRK2	6
157680	VPS13B	5
841	CASP8	2
3065	HDAC1	1
4609	MYC	1
90956	ADCK2	3
2624	GATA2	3
5789	PTPRD	4
8021	NUP214	3
1459	CSNK2A2	2
894	CCND2	2
283629	TSSK4	3
29951	PDZRN4	2
6776	STAT5A	2
79759	ZNF668	3
2189	FANCG	3
5156	PDGFRA	2
204851	HIPK1	1
7917	BAG6	1
93627	TBCK	2
137872	ADHFE1	3
27330	RPS6KA6	3
673	BRAF	1
57082	KNL1	6
1981	EIF4G1	5
6011	GRK1	4
1769	DNAH8	4
22976	PAXIP1	4
120892	LRRK2	1
65268	WNK2	3
7027	TFDP1	1
5205	ATP8B1	3
8178	ELL	3
4298	MLLT1	2
9321	TRIP11	3
9843	HEPH	1
8491	MAP4K3	3
9509	ADAMTS2	3
23396	PIP5K1C	1
23742	NPAP1	3
23049	SMG1	2
1487	CTBP1	3
2316	FLNA	3
8888	MCM3AP	1
80124	VCPIP1	4
100187828	HBD	3
23281	MTUS2	1
3554	IL1R1	3
2897	GRIK1	1
4317	MMP8	6
6146	RPL22	2
5896	RAG1	3
9344	TAOK2	2
23090	ZNF423	3
6498	SKIL	3
8522	GAS7	2
79834	PEAK1	2
10257	ABCC4	3
85415	RHPN2	5
55359	STYK1	3
6787	NEK4	3
2277	VEGFD	2
23411	SIRT1	3
57820	CCNB1IP1	1
23305	ACSL6	4
5588	PRKCQ	3
7248	TSC1	4
2869	GRK5	3
5923	RASGRF1	5
4774	NFIA	3
317	APAF1	3
2690	GHR	3
9021	SOCS3	1
100124696	TEC	3
9223	MAGI1	3
7094	TLN1	3
1281	COL3A1	4
9659	PDE4DIP	3
9201	DCLK1	3
63976	PRDM16	2
54101	RIPK4	2
2194	FASN	3
4628	MYH10	3
2213	FCGR2B	1
5587	PRKD1	4
5170	PDPK1	1
2304	FOXE1	3
22982	DIP2C	3
7227	TRPS1	4
1627	DBN1	2
3709	ITPR2	1
6778	STAT6	2
57118	CAMK1D	3
23301	EHBP1	5
3984	LIMK1	2
8428	STK24	1
3552	IL1A	2
3977	LIFR	1
5915	RARB	3
330	BIRC3	6
7112	TMPO	3
8536	CAMK1	3
2122	MECOM	2
2903	GRIN2A	2
5925	RB1	6
7124	TNF	1
5584	PRKCI	3
1026	CDKN1A	3
862	RUNX1T1	6
8661	EIF3A	2
7403	KDM6A	3
81629	TSSK3	3
255239	ANKK1	3
3716	JAK1	3
3488	IGFBP5	2
2011	MARK2	2
23092	ARHGAP26	3
4299	AFF1	2
2651	GCNT2	1
11086	ADAM29	2
2261	FGFR3	2
3237	HOXD11	3
4841	NONO	4
1612	DAPK1	2
55791	LRIF1	2
973	CD79A	3
23031	MAST3	3
814	CAMK4	3
3679	ITGA7	3
1608	DGKG	2
2178	FANCE	3
83732	RIOK1	3
29110	TBK1	1
1499	CTNNB1	10
4916	NTRK3	2
5624	PROC	2
5970	RELA	4

Gene in drug-gene network: Network Plot

Models in Neopeltolide

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.