DNAH8
Summary: The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012].
Loading, please wait...
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:603337 Ensembl IDEnsembl:ENSG00000124721 HGNC IDHGNC:HGNC:2952 PHARMGKB IDPA27405 Map Location6p21.2 | |||||
GO terms in DNAH8
Loading, please wait...
Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | NAS | GO:0003777 | microtubule motor activity |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IBA | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed |
| MF | IBA | GO:0045503 | dynein light chain binding |
| MF | IBA | GO:0045505 | dynein intermediate chain binding |
| MF | IBA | GO:0051959 | dynein light intermediate chain binding |
Gene expression in normal tissue: DNAH8
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in DNAH8
Loading, please wait...
Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa05016 | Huntington,s disease - Homo sapiens (human) |
| biocarta | lis1pathway | lissencephaly gene (lis1) in neuronal migration and development |
Showing 1 to 2 of 2 rows
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in DNAH8
Loading, please wait...
Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.