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iGMDRD268

Canonical SMILES: CC=CCC=CCCC(=O)C1C(O1)C(=O)N

InChI: InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1

InChI Key: GVEZIHKRYBHEFX-NQQPLRFYSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
Cerulenin	CHEMBL45627	5282050	Alone	Small Molecule

Drug Targets:

FASN HMGCS1

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
7514	XPO1	1
6664	SOX11	6
79848	CSPP1	2
6491	STIL	2
5261	PHKG2	2
132	ADK	6
2048	EPHB2	2
10806	SDCCAG8	4
55872	PBK	3
9706	ULK2	1
3845	KRAS	5
51347	TAOK3	3
4750	NEK1	2
23552	CDK20	3
23097	CDK19	3
8289	ARID1A	1
8266	UBL4A	2
2335	FN1	3
2475	MTOR	2
2176	FANCC	2
11160	ERLIN2	2
5079	PAX5	2
23235	SIK2	1
10863	ADAM28	3
1607	DGKB	2
55781	RIOK2	3
7253	TSHR	1
55534	MAML3	3
9816	URB2	2
80122	MAP3K19	2
1387	CREBBP	5
5756	TWF1	1
2043	EPHA4	3
5788	PTPRC	3
5579	PRKCB	6
11200	CHEK2	3
31	ACACA	2
9699	RIMS2	1
2977	GUCY1A2	1
10438	C1D	2
7373	COL14A1	3
5166	PDK4	2
5605	MAP2K2	3
7158	TP53BP1	1
6927	HNF1A	1
641	BLM	2
23522	KAT6B	6
10818	FRS2	1
102	ADAM10	2
4610	MYCL	6
3976	LIF	3
816	CAMK2B	2
55819	RNF130	3
152137	CCDC50	2
1540	CYLD	2
122011	CSNK1A1L	2
9693	RAPGEF2	5
646643	SBK2	3
1586	CYP17A1	1
5613	PRKX	2
22806	IKZF3	2
4005	LMO2	1
22984	PDCD11	2
6091	ROBO1	3
10217	CTDSPL	1
29904	EEF2K	3
1984	EIF5A	3
284217	LAMA1	4
375449	MAST4	3
94103	ORMDL3	2
983	CDK1	1
6850	SYK	2
92	ACVR2A	2
5286	PIK3C2A	2
50488	MINK1	6
2068	ERCC2	2
5568	PRKACG	2
2580	GAK	3
5165	PDK3	3
139285	AMER1	2
8148	TAF15	3
5924	RASGRF2	2
4058	LTK	2
1123	CHN1	3
5450	POU2AF1	5
2272	FHIT	5
27436	EML4	3
8576	STK16	3
27347	STK39	2
3932	LCK	1
6092	ROBO2	1
4602	MYB	1
4855	NOTCH4	2
6794	STK11	5
8218	CLTCL1	3
3791	KDR	4
4086	SMAD1	1
7409	VAV1	3
65243	ZFP69B	7
344387	CDKL4	3
863	CBFA2T3	3
8874	ARHGEF7	2
1555	CYP2B6	1
51086	TNNI3K	2
7175	TPR	2
80205	CHD9	4
2000	ELF4	3
8997	KALRN	5
4437	MSH3	4
5371	PML	2
54658	UGT1A1	1
10948	STARD3	2
78989	COLEC11	2
23373	CRTC1	3
285220	EPHA6	4
5297	PI4KA	3
10926	DBF4	2
10535	RNASEH2A	2
64840	PORCN	2
340533	NEXMIF	1
5578	PRKCA	2
9972	NUP153	3
3239	HOXD13	2
5290	PIK3CA	1
3720	JARID2	2
4293	MAP3K9	1
253260	RICTOR	2
10565	ARFGEF1	3
57154	SMURF1	3
5530	PPP3CA	3
7075	TIE1	3
640	BLK	2
90956	ADCK2	3
1459	CSNK2A2	2
8682	PEA15	1
7297	TYK2	2
894	CCND2	2
7443	VRK1	2
3635	INPP5D	2
1544	CYP1A2	6
10000	AKT3	4
6872	TAF1	2
673	BRAF	2
6011	GRK1	3
84879	MFSD2A	5
1769	DNAH8	2
22976	PAXIP1	2
23532	PRAME	2
120892	LRRK2	3
7027	TFDP1	3
6095	RORA	3
7301	TYRO3	1
5205	ATP8B1	1
9113	LATS1	3
460	ASTN1	2
5294	PIK3CG	6
9509	ADAMTS2	3
5563	PRKAA2	2
55521	TRIM36	2
5728	PTEN	2
1487	CTBP1	3
7030	TFE3	3
7155	TOP2B	2
80124	VCPIP1	3
667	DST	5
1974	EIF4A2	3
4317	MMP8	2
79834	PEAK1	2
7036	TFR2	6
55359	STYK1	3
6787	NEK4	2
53904	MYO3A	3
79012	CAMKV	2
9372	ZFYVE9	6
2046	EPHA8	2
10249	GLYAT	2
558	AXL	1
7248	TSC1	1
1399	CRKL	1
2690	GHR	3
10111	RAD50	1
2049	EPHB3	3
283455	KSR2	3
6093	ROCK1	2
2130	EWSR1	2
1719	DHFR	4
2304	FOXE1	3
3717	JAK2	2
1627	DBN1	2
3552	IL1A	1
80216	ALPK1	5
444	ASPH	3
7046	TGFBR1	3
5087	PBX1	2
9894	TELO2	3
1026	CDKN1A	3
2065	ERBB3	2
7403	KDM6A	3
81629	TSSK3	3
255239	ANKK1	2
2011	MARK2	2
9935	MAFB	2
142	PARP1	1
5260	PHKG1	1
10891	PPARGC1A	1
973	CD79A	3
5287	PIK3C2B	2
23031	MAST3	2
4629	MYH11	6
4780	NFE2L2	1
6868	ADAM17	1
23112	TNRC6B	1
29110	TBK1	1
5885	RAD21	5
3440	IFNA2	2

Gene in drug-gene network: Network Plot

Models in Cerulenin

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DATATYPES

CLASSFICATION

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