STYK1
Summary: Receptor protein tyrosine kinases, like STYK1, play important roles in diverse cellular and developmental processes, such as cell proliferation, differentiation, and survival (Liu et al., 2004 [PubMed 15150103]).[supplied by OMIM, Mar 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| serine/threonine/tyrosine kinase 1 | MIM:611433 | Ensembl:ENSG00000060140 | HGNC:HGNC:18889 | PA134976821 | 12p13.2 |
GO terms in STYK1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
| MF | IBA | GO:0005102 | signaling receptor binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| CC | IDA | GO:0005886 | plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IBA | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane |
| BP | IBA | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway |
| BP | IBA | GO:0016477 | cell migration |
| BP | IBA | GO:0030154 | cell differentiation |
| BP | IBA | GO:0038083 | peptidyl-tyrosine autophosphorylation |
| BP | IBA | GO:0042127 | regulation of cell proliferation |
| BP | IBA | GO:0045087 | innate immune response |
Gene expression in normal tissue: STYK1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD494 | Neopeltolide | 3 |
| iGMDRD532 | Olaparib | 3 |
| iGMDRD425 | ERASTIN | 3 |
| iGMDRD772 | BRD4770 | 3 |
| iGMDRD607 | Ubistatin B | 3 |
| iGMDRD512 | nutlin 3 | 3 |
| iGMDRD330 | BRD4132 | 1 |
| iGMDRD132 | (-)-gallocatechin-3-O-gallate | 1 |
| iGMDRD466 | Chaetocin | 1 |
| iGMDRD61 | Kinetin riboside | 6 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD294 | Batimastat | 3 |
| iGMDRD213 | SMR000068650 | 3 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 3 |
| iGMDRD171 | Pemetrexed | 3 |
| iGMDRD6 | AM-580 | 3 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD220 | fumonisin B1 | 3 |
| iGMDRD451 | Serdemetan | 3 |
| iGMDRD268 | Cerulenin | 3 |
| iGMDRD147 | Prima-1 | 3 |
| iGMDRD690 | PRIMA-1MET | 3 |
| iGMDRD398 | Sepantronium | 3 |
| iGMDRD662 | JQ-1 | 3 |
| iGMDRD74 | Idarubicin | 3 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in STYK1
CLASSFICATION
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