iGMDRD425
| Standard Name | CHEMBL | Pubchem CID | Drug Status | Drug Type |
|---|---|---|---|---|
| ERASTIN | CHEMBL401989 | 11214900 | Alone | Small Molecule |
Drug Pathways:
FerroptosisDrug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 7514 | XPO1 | 1 |
| 10221 | TRIB1 | 3 |
| 9706 | ULK2 | 1 |
| 4750 | NEK1 | 3 |
| 8266 | UBL4A | 2 |
| 3939 | LDHA | 2 |
| 51129 | ANGPTL4 | 2 |
| 79092 | CARD14 | 1 |
| 5079 | PAX5 | 3 |
| 10863 | ADAM28 | 3 |
| 4170 | MCL1 | 1 |
| 80122 | MAP3K19 | 1 |
| 2043 | EPHA4 | 1 |
| 9699 | RIMS2 | 2 |
| 4851 | NOTCH1 | 1 |
| 57670 | KIAA1549 | 3 |
| 340156 | MYLK4 | 1 |
| 5081 | PAX7 | 1 |
| 5900 | RALGDS | 3 |
| 11073 | TOPBP1 | 2 |
| 22806 | IKZF3 | 3 |
| 6091 | ROBO1 | 3 |
| 5984 | RFC4 | 3 |
| 10188 | TNK2 | 2 |
| 11169 | WDHD1 | 3 |
| 57476 | GRAMD1B | 1 |
| 23191 | CYFIP1 | 1 |
| 1452 | CSNK1A1 | 1 |
| 57510 | XPO5 | 2 |
| 1973 | EIF4A1 | 3 |
| 9590 | AKAP12 | 2 |
| 6917 | TCEA1 | 1 |
| 5229 | PGGT1B | 1 |
| 5924 | RASGRF2 | 2 |
| 4087 | SMAD2 | 2 |
| 5450 | POU2AF1 | 2 |
| 2066 | ERBB4 | 2 |
| 5863 | RGL2 | 2 |
| 7157 | TP53 | 4 |
| 6794 | STK11 | 1 |
| 64386 | MMP25 | 1 |
| 369 | ARAF | 2 |
| 65125 | WNK1 | 4 |
| 4437 | MSH3 | 5 |
| 54658 | UGT1A1 | 2 |
| 4293 | MAP3K9 | 2 |
| 5366 | PMAIP1 | 3 |
| 1956 | EGFR | 3 |
| 4609 | MYC | 4 |
| 64333 | ARHGAP9 | 1 |
| 90956 | ADCK2 | 3 |
| 894 | CCND2 | 1 |
| 5663 | PSEN1 | 1 |
| 5156 | PDGFRA | 2 |
| 23532 | PRAME | 4 |
| 780 | DDR1 | 2 |
| 7301 | TYRO3 | 1 |
| 93273 | LEMD1 | 3 |
| 23118 | TAB2 | 3 |
| 55290 | BRF2 | 3 |
| 8621 | CDK13 | 2 |
| 10010 | TANK | 2 |
| 7030 | TFE3 | 3 |
| 7465 | WEE1 | 3 |
| 55359 | STYK1 | 3 |
| 79012 | CAMKV | 1 |
| 22843 | PPM1E | 1 |
| 2317 | FLNB | 3 |
| 7094 | TLN1 | 1 |
| 2049 | EPHB3 | 1 |
| 6093 | ROCK1 | 3 |
| 1719 | DHFR | 5 |
| 3717 | JAK2 | 2 |
| 3709 | ITPR2 | 3 |
| 2719 | GPC3 | 2 |
| 80216 | ALPK1 | 4 |
| 444 | ASPH | 1 |
| 7124 | TNF | 3 |
| 2065 | ERBB3 | 1 |
| 7403 | KDM6A | 3 |
| 2308 | FOXO1 | 3 |
| 595 | CCND1 | 3 |
| 10891 | PPARGC1A | 2 |
| 94 | ACVRL1 | 1 |
| 6426 | SRSF1 | 1 |
| 5685 | PSMA4 | 3 |
Gene in drug-gene network: Network Plot
Models in ERASTIN
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.