TCEA1
Summary:
Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
---|---|---|---|---|---|
transcription elongation factor A1 | MIM:601425 | Ensembl:ENSG00000187735 | HGNC:HGNC:11612 | PA36371 | 8q11.23 |
GO terms in TCEA1
Term Type | Evidence Type | GO Term ID | GO Des. |
---|---|---|---|
BP | TAS | GO:0006283 | transcription-coupled nucleotide-excision repair |
BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
BP | TAS | GO:0006366 | transcription by RNA polymerase II |
BP | TAS | GO:0006368 | transcription elongation from RNA polymerase II promoter |
BP | IEA | GO:1901919 | positive regulation of exoribonuclease activity |
CC | IDA | GO:0005634 | nucleus |
CC | TAS | GO:0005654 | nucleoplasm |
CC | IDA | GO:0005669 | transcription factor TFIID complex |
CC | IDA | GO:0005730 | nucleolus |
MF | IEA | GO:0003677 | DNA binding |
MF | IPI | GO:0005515 | protein binding |
MF | IEA | GO:0008270 | zinc ion binding |
Gene expression in normal tissue: TCEA1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TCEA1
Database | Pathway ID | Pathway Des. |
---|---|---|
reactome | R-HSA-112382 | Formation of RNA Pol II elongation complex |
reactome | R-HSA-162587 | HIV Life Cycle |
reactome | R-HSA-162599 | Late Phase of HIV Life Cycle |
reactome | R-HSA-162906 | HIV Infection |
reactome | R-HSA-1643685 | Disease |
reactome | R-HSA-167152 | Formation of HIV elongation complex in the absence of HIV Tat |
reactome | R-HSA-167169 | HIV Transcription Elongation |
reactome | R-HSA-167172 | Transcription of the HIV genome |
reactome | R-HSA-167200 | Formation of HIV-1 elongation complex containing HIV-1 Tat |
reactome | R-HSA-167238 | Pausing and recovery of Tat-mediated HIV elongation |
reactome | R-HSA-167243 | Tat-mediated HIV elongation arrest and recovery |
reactome | R-HSA-167246 | Tat-mediated elongation of the HIV-1 transcript |
reactome | R-HSA-167287 | HIV elongation arrest and recovery |
reactome | R-HSA-167290 | Pausing and recovery of HIV elongation |
reactome | R-HSA-212436 | Generic Transcription Pathway |
reactome | R-HSA-3700989 | Transcriptional Regulation by TP53 |
reactome | R-HSA-5663205 | Infectious disease |
reactome | R-HSA-5696398 | Nucleotide Excision Repair |
reactome | R-HSA-674695 | RNA Polymerase II Pre-transcription Events |
reactome | R-HSA-6781823 | Formation of TC-NER Pre-Incision Complex |
reactome | R-HSA-6781827 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
reactome | R-HSA-6782135 | Dual incision in TC-NER |
reactome | R-HSA-6782210 | Gap-filling DNA repair synthesis and ligation in TC-NER |
reactome | R-HSA-6796648 | TP53 Regulates Transcription of DNA Repair Genes |
reactome | R-HSA-73857 | RNA Polymerase II Transcription |
reactome | R-HSA-73894 | DNA Repair |
reactome | R-HSA-74160 | Gene expression (Transcription) |
reactome | R-HSA-75955 | RNA Polymerase II Transcription Elongation |
Gene-Drug: Aster Plot
Drug ID | Drug Name | Model Num. |
---|---|---|
iGMDRD137 | Indisulam | 8 |
iGMDRD158 | NSC141540 | 6 |
iGMDRD147 | Prima-1 | 3 |
iGMDRD886 | Compound 1541A | 2 |
iGMDRD300 | Tozasertib | 2 |
iGMDRD872 | BRD7137 | 5 |
iGMDRD871 | BRD6368 | 6 |
iGMDRD286 | Nsc 632839 | 2 |
iGMDRD79 | Gemcitabine | 6 |
iGMDRD532 | Olaparib | 3 |
iGMDRD148 | Pifithrin-mu | 3 |
iGMDRD307 | Manumycin A | 6 |
iGMDRD177 | Teniposide | 3 |
iGMDRD123 | Isoevodiamine | 3 |
iGMDRD901 | ELCPK | 3 |
iGMDRD341 | Triacsin c | 4 |
iGMDRD318 | PAC-1 | 6 |
iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 6 |
iGMDRD255 | SB225002 | 2 |
iGMDRD138 | PX 12 | 3 |
iGMDRD474 | Avrainvillamide | 5 |
iGMDRD64 | Parbendazole | 3 |
iGMDRD690 | PRIMA-1MET | 6 |
iGMDRD188 | Piperlongumine | 6 |
iGMDRD546 | BMS-754807 | 3 |
iGMDRD144 | NSC95397 | 4 |
iGMDRD427 | ABT737 | 2 |
iGMDRD425 | ERASTIN | 1 |
iGMDRD1008 | SR-II-138A | 3 |
iGMDRD889 | Compound 7d-cis | 6 |
iGMDRD126 | Tipifarnib | 2 |
iGMDRD394 | BX-795 | 1 |
iGMDRD193 | Fqi1 | 3 |
iGMDRD201 | SKI II | 1 |
iGMDRD446 | LY 2183240 | 4 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TCEA1