TCEA1
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| transcription elongation factor A1 | MIM:601425 | Ensembl:ENSG00000187735 | HGNC:HGNC:11612 | PA36371 | 8q11.23 |
GO terms in TCEA1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | TAS | GO:0006283 | transcription-coupled nucleotide-excision repair |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | TAS | GO:0006366 | transcription by RNA polymerase II |
| BP | TAS | GO:0006368 | transcription elongation from RNA polymerase II promoter |
| BP | IEA | GO:1901919 | positive regulation of exoribonuclease activity |
| CC | IDA | GO:0005634 | nucleus |
| CC | TAS | GO:0005654 | nucleoplasm |
| CC | IDA | GO:0005669 | transcription factor TFIID complex |
| CC | IDA | GO:0005730 | nucleolus |
| MF | IEA | GO:0003677 | DNA binding |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0008270 | zinc ion binding |
Gene expression in normal tissue: TCEA1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in TCEA1
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| reactome | R-HSA-112382 | Formation of RNA Pol II elongation complex |
| reactome | R-HSA-162587 | HIV Life Cycle |
| reactome | R-HSA-162599 | Late Phase of HIV Life Cycle |
| reactome | R-HSA-162906 | HIV Infection |
| reactome | R-HSA-1643685 | Disease |
| reactome | R-HSA-167152 | Formation of HIV elongation complex in the absence of HIV Tat |
| reactome | R-HSA-167169 | HIV Transcription Elongation |
| reactome | R-HSA-167172 | Transcription of the HIV genome |
| reactome | R-HSA-167200 | Formation of HIV-1 elongation complex containing HIV-1 Tat |
| reactome | R-HSA-167238 | Pausing and recovery of Tat-mediated HIV elongation |
| reactome | R-HSA-167243 | Tat-mediated HIV elongation arrest and recovery |
| reactome | R-HSA-167246 | Tat-mediated elongation of the HIV-1 transcript |
| reactome | R-HSA-167287 | HIV elongation arrest and recovery |
| reactome | R-HSA-167290 | Pausing and recovery of HIV elongation |
| reactome | R-HSA-212436 | Generic Transcription Pathway |
| reactome | R-HSA-3700989 | Transcriptional Regulation by TP53 |
| reactome | R-HSA-5663205 | Infectious disease |
| reactome | R-HSA-5696398 | Nucleotide Excision Repair |
| reactome | R-HSA-674695 | RNA Polymerase II Pre-transcription Events |
| reactome | R-HSA-6781823 | Formation of TC-NER Pre-Incision Complex |
| reactome | R-HSA-6781827 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) |
| reactome | R-HSA-6782135 | Dual incision in TC-NER |
| reactome | R-HSA-6782210 | Gap-filling DNA repair synthesis and ligation in TC-NER |
| reactome | R-HSA-6796648 | TP53 Regulates Transcription of DNA Repair Genes |
| reactome | R-HSA-73857 | RNA Polymerase II Transcription |
| reactome | R-HSA-73894 | DNA Repair |
| reactome | R-HSA-74160 | Gene expression (Transcription) |
| reactome | R-HSA-75955 | RNA Polymerase II Transcription Elongation |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD137 | Indisulam | 8 |
| iGMDRD158 | NSC141540 | 6 |
| iGMDRD147 | Prima-1 | 3 |
| iGMDRD886 | Compound 1541A | 2 |
| iGMDRD300 | Tozasertib | 2 |
| iGMDRD872 | BRD7137 | 5 |
| iGMDRD871 | BRD6368 | 6 |
| iGMDRD286 | Nsc 632839 | 2 |
| iGMDRD79 | Gemcitabine | 6 |
| iGMDRD532 | Olaparib | 3 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD307 | Manumycin A | 6 |
| iGMDRD177 | Teniposide | 3 |
| iGMDRD123 | Isoevodiamine | 3 |
| iGMDRD901 | ELCPK | 3 |
| iGMDRD341 | Triacsin c | 4 |
| iGMDRD318 | PAC-1 | 6 |
| iGMDRD801 | 2,4-dideoxy-DC-45-A2 | 6 |
| iGMDRD255 | SB225002 | 2 |
| iGMDRD138 | PX 12 | 3 |
| iGMDRD474 | Avrainvillamide | 5 |
| iGMDRD64 | Parbendazole | 3 |
| iGMDRD690 | PRIMA-1MET | 6 |
| iGMDRD188 | Piperlongumine | 6 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD144 | NSC95397 | 4 |
| iGMDRD427 | ABT737 | 2 |
| iGMDRD425 | ERASTIN | 1 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD889 | Compound 7d-cis | 6 |
| iGMDRD126 | Tipifarnib | 2 |
| iGMDRD394 | BX-795 | 1 |
| iGMDRD193 | Fqi1 | 3 |
| iGMDRD201 | SKI II | 1 |
| iGMDRD446 | LY 2183240 | 4 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in TCEA1
CLASSFICATION
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