iGMDRD871
| Standard Name | Drug Status |
|---|---|
| BRD6368 | Alone |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 5 |
| 3696 | ITGB8 | 3 |
| 4854 | NOTCH3 | 1 |
| 6664 | SOX11 | 6 |
| 10460 | TACC3 | 3 |
| 5027 | P2RX7 | 2 |
| 997 | CDC34 | 3 |
| 7837 | PXDN | 5 |
| 10221 | TRIB1 | 3 |
| 1464 | CSPG4 | 3 |
| 10641 | NPRL2 | 3 |
| 23085 | ERC1 | 3 |
| 6491 | STIL | 3 |
| 21 | ABCA3 | 9 |
| 132 | ADK | 8 |
| 6774 | STAT3 | 3 |
| 5933 | RBL1 | 3 |
| 6319 | SCD | 3 |
| 11183 | MAP4K5 | 1 |
| 2986 | GUCY2F | 3 |
| 79947 | DHDDS | 3 |
| 4627 | MYH9 | 3 |
| 8929 | PHOX2B | 3 |
| 23513 | SCRIB | 3 |
| 2956 | MSH6 | 1 |
| 51765 | STK26 | 6 |
| 57679 | ALS2 | 2 |
| 220064 | LTO1 | 3 |
| 399 | RHOH | 3 |
| 10783 | NEK6 | 3 |
| 4477 | MSMB | 3 |
| 1520 | CTSS | 1 |
| 57554 | LRRC7 | 2 |
| 9706 | ULK2 | 2 |
| 7272 | TTK | 8 |
| 93 | ACVR2B | 2 |
| 347365 | ITIH6 | 1 |
| 3845 | KRAS | 6 |
| 51347 | TAOK3 | 2 |
| 4750 | NEK1 | 4 |
| 5295 | PIK3R1 | 1 |
| 2100 | ESR2 | 3 |
| 55215 | FANCI | 3 |
| 8289 | ARID1A | 6 |
| 80070 | ADAMTS20 | 3 |
| 8573 | CASK | 5 |
| 3939 | LDHA | 2 |
| 51231 | VRK3 | 3 |
| 25778 | DSTYK | 3 |
| 84700 | MYO18B | 3 |
| 4928 | NUP98 | 4 |
| 5593 | PRKG2 | 3 |
| 79092 | CARD14 | 3 |
| 53616 | ADAM22 | 2 |
| 4312 | MMP1 | 2 |
| 9760 | TOX | 5 |
| 6597 | SMARCA4 | 6 |
| 150209 | AIFM3 | 1 |
| 3551 | IKBKB | 2 |
| 3326 | HSP90AB1 | 3 |
| 4036 | LRP2 | 3 |
| 8780 | RIOK3 | 4 |
| 390502 | SERPINA2 | 1 |
| 56776 | FMN2 | 2 |
| 5079 | PAX5 | 2 |
| 64783 | RBM15 | 2 |
| 4771 | NF2 | 3 |
| 10863 | ADAM28 | 3 |
| 4170 | MCL1 | 1 |
| 1607 | DGKB | 6 |
| 23213 | SULF1 | 7 |
| 22853 | LMTK2 | 2 |
| 7253 | TSHR | 6 |
| 5298 | PI4KB | 5 |
| 2241 | FER | 4 |
| 8737 | RIPK1 | 3 |
| 22821 | RASA3 | 8 |
| 6455 | SH3GL1 | 3 |
| 114908 | TMEM123 | 6 |
| 7048 | TGFBR2 | 1 |
| 2249 | FGF4 | 8 |
| 112858 | TP53RK | 2 |
| 1387 | CREBBP | 10 |
| 1893 | ECM1 | 3 |
| 127933 | UHMK1 | 2 |
| 1859 | DYRK1A | 6 |
| 2885 | GRB2 | 2 |
| 2313 | FLI1 | 3 |
| 56164 | STK31 | 2 |
| 4881 | NPR1 | 4 |
| 5579 | PRKCB | 6 |
| 11200 | CHEK2 | 3 |
| 31 | ACACA | 5 |
| 7133 | TNFRSF1B | 7 |
| 1602 | DACH1 | 2 |
| 10178 | TENM1 | 5 |
| 51755 | CDK12 | 1 |
| 9048 | ARTN | 3 |
| 5074 | PAWR | 1 |
| 29998 | BICRA | 2 |
| 8295 | TRRAP | 2 |
| 2977 | GUCY1A2 | 3 |
| 11122 | PTPRT | 2 |
| 27148 | STK36 | 2 |
| 5159 | PDGFRB | 6 |
| 5166 | PDK4 | 3 |
| 7173 | TPO | 2 |
| 51512 | GTSE1 | 3 |
| 139378 | ADGRG4 | 10 |
| 974 | CD79B | 3 |
| 10746 | MAP3K2 | 3 |
| 83439 | TCF7L1 | 3 |
| 1454 | CSNK1E | 3 |
| 23522 | KAT6B | 4 |
| 55728 | N4BP2 | 6 |
| 25865 | PRKD2 | 3 |
| 10006 | ABI1 | 2 |
| 284521 | OR2L13 | 3 |
| 816 | CAMK2B | 2 |
| 5081 | PAX7 | 2 |
| 342667 | STAC2 | 1 |
| 5607 | MAP2K5 | 3 |
| 5900 | RALGDS | 3 |
| 152137 | CCDC50 | 3 |
| 256646 | NUTM1 | 1 |
| 2268 | FGR | 3 |
| 8767 | RIPK2 | 6 |
| 1880 | GPR183 | 4 |
| 9693 | RAPGEF2 | 2 |
| 169436 | STKLD1 | 6 |
| 222484 | LNX2 | 1 |
| 8549 | LGR5 | 4 |
| 3714 | JAG2 | 3 |
| 8852 | AKAP4 | 3 |
| 5613 | PRKX | 2 |
| 329 | BIRC2 | 6 |
| 26353 | HSPB8 | 2 |
| 2242 | FES | 6 |
| 166614 | DCLK2 | 3 |
| 22984 | PDCD11 | 4 |
| 6041 | RNASEL | 1 |
| 9175 | MAP3K13 | 6 |
| 200576 | PIKFYVE | 4 |
| 80351 | TNKS2 | 4 |
| 8313 | AXIN2 | 3 |
| 6091 | ROBO1 | 4 |
| 116986 | AGAP2 | 3 |
| 5330 | PLCB2 | 3 |
| 730249 | ACOD1 | 3 |
| 5984 | RFC4 | 3 |
| 9636 | ISG15 | 6 |
| 4216 | MAP3K4 | 6 |
| 2736 | GLI2 | 6 |
| 2908 | NR3C1 | 2 |
| 4194 | MDM4 | 2 |
| 284217 | LAMA1 | 7 |
| 83931 | STK40 | 2 |
| 2045 | EPHA7 | 3 |
| 1992 | SERPINB1 | 6 |
| 399979 | SNX19 | 3 |
| 375449 | MAST4 | 6 |
| 2064 | ERBB2 | 5 |
| 6850 | SYK | 3 |
| 287015 | TRIM42 | 7 |
| 65217 | PCDH15 | 1 |
| 26750 | RPS6KC1 | 3 |
| 54899 | PXK | 6 |
| 286826 | LIN9 | 3 |
| 23387 | SIK3 | 3 |
| 338322 | NLRP10 | 3 |
| 1456 | CSNK1G3 | 3 |
| 783 | CACNB2 | 5 |
| 6416 | MAP2K4 | 6 |
| 7525 | YES1 | 6 |
| 1452 | CSNK1A1 | 3 |
| 6709 | SPTAN1 | 3 |
| 8215 | DVL1P1 | 3 |
| 2068 | ERCC2 | 3 |
| 6098 | ROS1 | 6 |
| 130497 | OSR1 | 3 |
| 9590 | AKAP12 | 2 |
| 6917 | TCEA1 | 6 |
| 3667 | IRS1 | 3 |
| 472 | ATM | 3 |
| 2580 | GAK | 2 |
| 139285 | AMER1 | 2 |
| 83903 | HASPIN | 2 |
| 8148 | TAF15 | 2 |
| 575 | ADGRB1 | 3 |
| 53942 | CNTN5 | 4 |
| 2734 | GLG1 | 4 |
| 9096 | TBX18 | 2 |
| 9564 | BCAR1 | 2 |
| 1496 | CTNNA2 | 1 |
| 7010 | TEK | 3 |
| 5450 | POU2AF1 | 1 |
| 898 | CCNE1 | 2 |
| 23152 | CIC | 2 |
| 2050 | EPHB4 | 3 |
| 2272 | FHIT | 6 |
| 839 | CASP6 | 3 |
| 5863 | RGL2 | 5 |
| 10290 | SPEG | 3 |
| 2201 | FBN2 | 2 |
| 9794 | MAML1 | 2 |
| 27436 | EML4 | 5 |
| 157753 | TMEM74 | 8 |
| 57523 | NYNRIN | 4 |
| 1910 | EDNRB | 3 |
| 5336 | PLCG2 | 3 |
| 10018 | BCL2L11 | 5 |
| 27347 | STK39 | 2 |
| 648 | BMI1 | 3 |
| 2099 | ESR1 | 3 |
| 27086 | FOXP1 | 3 |
| 4602 | MYB | 2 |
| 25836 | NIPBL | 2 |
| 7869 | SEMA3B | 4 |
| 5910 | RAP1GDS1 | 6 |
| 3791 | KDR | 3 |
| 114788 | CSMD3 | 2 |
| 2263 | FGFR2 | 1 |
| 130399 | ACVR1C | 3 |
| 225689 | MAPK15 | 2 |
| 65243 | ZFP69B | 2 |
| 84075 | FSCB | 2 |
| 9967 | THRAP3 | 4 |
| 124540 | MSI2 | 3 |
| 1045 | CDX2 | 1 |
| 1555 | CYP2B6 | 1 |
| 1102 | RCBTB2 | 2 |
| 9088 | PKMYT1 | 9 |
| 5600 | MAPK11 | 1 |
| 7038 | TG | 2 |
| 57188 | ADAMTSL3 | 2 |
| 3187 | HNRNPH1 | 2 |
| 65125 | WNK1 | 1 |
| 57591 | MRTFA | 3 |
| 136332 | LRGUK | 2 |
| 4436 | MSH2 | 1 |
| 676 | BRDT | 2 |
| 5871 | MAP4K2 | 12 |
| 2081 | ERN1 | 9 |
| 8997 | KALRN | 2 |
| 57551 | TAOK1 | 2 |
| 6280 | S100A9 | 2 |
| 23469 | PHF3 | 7 |
| 4089 | SMAD4 | 3 |
| 51284 | TLR7 | 2 |
| 6654 | SOS1 | 2 |
| 1616 | DAXX | 2 |
| 2668 | GDNF | 3 |
| 4139 | MARK1 | 2 |
| 7204 | TRIO | 3 |
| 139760 | GPR119 | 5 |
| 78989 | COLEC11 | 2 |
| 285220 | EPHA6 | 2 |
| 546 | ATRX | 5 |
| 2047 | EPHB1 | 2 |
| 54756 | IL17RD | 5 |
| 7786 | MAP3K12 | 1 |
| 1978 | EIF4EBP1 | 3 |
| 10926 | DBF4 | 2 |
| 64840 | PORCN | 2 |
| 4958 | OMD | 3 |
| 30827 | CXXC1 | 3 |
| 56997 | COQ8A | 2 |
| 57144 | PAK5 | 3 |
| 5578 | PRKCA | 3 |
| 8216 | LZTR1 | 3 |
| 9972 | NUP153 | 2 |
| 3239 | HOXD13 | 3 |
| 50615 | IL21R | 2 |
| 84823 | LMNB2 | 3 |
| 5290 | PIK3CA | 2 |
| 1687 | GSDME | 5 |
| 8202 | NCOA3 | 2 |
| 26524 | LATS2 | 3 |
| 253260 | RICTOR | 9 |
| 5366 | PMAIP1 | 3 |
| 5045 | FURIN | 2 |
| 64919 | BCL11B | 4 |
| 675 | BRCA2 | 1 |
| 7075 | TIE1 | 2 |
| 157680 | VPS13B | 2 |
| 2735 | GLI1 | 3 |
| 4609 | MYC | 1 |
| 64750 | SMURF2 | 2 |
| 90956 | ADCK2 | 3 |
| 5789 | PTPRD | 2 |
| 5599 | MAPK8 | 3 |
| 8021 | NUP214 | 2 |
| 1459 | CSNK2A2 | 6 |
| 10461 | MERTK | 3 |
| 51321 | AMZ2 | 1 |
| 6725 | SRMS | 2 |
| 1326 | MAP3K8 | 6 |
| 26278 | SACS | 5 |
| 5592 | PRKG1 | 9 |
| 1594 | CYP27B1 | 4 |
| 7443 | VRK1 | 2 |
| 204851 | HIPK1 | 6 |
| 3635 | INPP5D | 2 |
| 1653 | DDX1 | 3 |
| 8900 | CCNA1 | 2 |
| 375056 | MIA3 | 3 |
| 10971 | YWHAQ | 3 |
| 1544 | CYP1A2 | 6 |
| 93627 | TBCK | 5 |
| 23005 | MAPKBP1 | 3 |
| 10186 | LHFPL6 | 1 |
| 6872 | TAF1 | 3 |
| 203102 | ADAM32 | 4 |
| 673 | BRAF | 1 |
| 1213 | CLTC | 2 |
| 4790 | NFKB1 | 3 |
| 4863 | NPAT | 2 |
| 57538 | ALPK3 | 5 |
| 6469 | SHH | 3 |
| 120892 | LRRK2 | 2 |
| 79184 | BRCC3 | 4 |
| 6095 | RORA | 4 |
| 29844 | TFPT | 6 |
| 84441 | MAML2 | 3 |
| 7301 | TYRO3 | 7 |
| 8029 | CUBN | 2 |
| 8626 | TP63 | 2 |
| 9113 | LATS1 | 2 |
| 7849 | PAX8 | 3 |
| 4298 | MLLT1 | 3 |
| 5979 | RET | 3 |
| 9321 | TRIP11 | 2 |
| 10253 | SPRY2 | 3 |
| 9843 | HEPH | 3 |
| 11262 | SP140 | 2 |
| 1230 | CCR1 | 2 |
| 157 | GRK3 | 2 |
| 266747 | RGL4 | 1 |
| 5563 | PRKAA2 | 5 |
| 23396 | PIP5K1C | 2 |
| 10010 | TANK | 2 |
| 8312 | AXIN1 | 5 |
| 23476 | BRD4 | 3 |
| 7155 | TOP2B | 2 |
| 1869 | E2F1 | 3 |
| 23281 | MTUS2 | 1 |
| 4004 | LMO1 | 3 |
| 3554 | IL1R1 | 4 |
| 53836 | GPR87 | 2 |
| 2897 | GRIK1 | 7 |
| 2188 | FANCF | 3 |
| 6146 | RPL22 | 1 |
| 2264 | FGFR4 | 3 |
| 177 | AGER | 3 |
| 5896 | RAG1 | 4 |
| 995 | CDC25C | 3 |
| 7465 | WEE1 | 3 |
| 7059 | THBS3 | 2 |
| 7454 | WAS | 5 |
| 7036 | TFR2 | 2 |
| 85415 | RHPN2 | 5 |
| 203447 | NRK | 3 |
| 2277 | VEGFD | 2 |
| 8667 | EIF3H | 6 |
| 23411 | SIRT1 | 3 |
| 3161 | HMMR | 3 |
| 10249 | GLYAT | 1 |
| 128869 | PIGU | 8 |
| 8821 | INPP4B | 3 |
| 221895 | JAZF1 | 6 |
| 8394 | PIP5K1A | 6 |
| 51151 | SLC45A2 | 3 |
| 5291 | PIK3CB | 4 |
| 558 | AXL | 2 |
| 7248 | TSC1 | 3 |
| 83417 | FCRL4 | 5 |
| 5581 | PRKCE | 3 |
| 5923 | RASGRF1 | 3 |
| 2317 | FLNB | 3 |
| 9223 | MAGI1 | 3 |
| 860 | RUNX2 | 3 |
| 1789 | DNMT3B | 2 |
| 7094 | TLN1 | 1 |
| 3181 | HNRNPA2B1 | 5 |
| 9659 | PDE4DIP | 1 |
| 63976 | PRDM16 | 6 |
| 54101 | RIPK4 | 2 |
| 283455 | KSR2 | 9 |
| 2130 | EWSR1 | 2 |
| 3624 | INHBA | 2 |
| 4628 | MYH10 | 5 |
| 598 | BCL2L1 | 4 |
| 5587 | PRKD1 | 1 |
| 55007 | FAM118A | 5 |
| 1719 | DHFR | 3 |
| 10734 | STAG3 | 2 |
| 6196 | RPS6KA2 | 2 |
| 2131 | EXT1 | 3 |
| 3717 | JAK2 | 4 |
| 7099 | TLR4 | 3 |
| 2157 | F8 | 4 |
| 7227 | TRPS1 | 2 |
| 53335 | BCL11A | 1 |
| 79837 | PIP4K2C | 4 |
| 6778 | STAT6 | 3 |
| 8428 | STK24 | 3 |
| 3516 | RBPJ | 3 |
| 6777 | STAT5B | 1 |
| 5932 | RBBP8 | 3 |
| 5915 | RARB | 5 |
| 4261 | CIITA | 6 |
| 4330 | MN1 | 5 |
| 23250 | ATP11A | 3 |
| 7046 | TGFBR1 | 2 |
| 80781 | COL18A1 | 7 |
| 8536 | CAMK1 | 6 |
| 2122 | MECOM | 3 |
| 3662 | IRF4 | 2 |
| 1515 | CTSV | 3 |
| 7124 | TNF | 3 |
| 5584 | PRKCI | 2 |
| 2065 | ERBB3 | 5 |
| 1576 | CYP3A4 | 3 |
| 7403 | KDM6A | 1 |
| 8717 | TRADD | 3 |
| 2308 | FOXO1 | 3 |
| 112268437 | LOC112268437 | 3 |
| 8841 | HDAC3 | 3 |
| 51364 | ZMYND10 | 3 |
| 197259 | MLKL | 2 |
| 7040 | TGFB1 | 5 |
| 55959 | SULF2 | 3 |
| 57120 | GOPC | 3 |
| 3488 | IGFBP5 | 2 |
| 3480 | IGF1R | 2 |
| 2011 | MARK2 | 2 |
| 4915 | NTRK2 | 3 |
| 11086 | ADAM29 | 2 |
| 142 | PARP1 | 2 |
| 865 | CBFB | 6 |
| 3237 | HOXD11 | 3 |
| 4040 | LRP6 | 3 |
| 55422 | ZNF331 | 4 |
| 4841 | NONO | 6 |
| 4763 | NF1 | 7 |
| 8814 | CDKL1 | 3 |
| 494551 | WEE2 | 3 |
| 1840 | DTX1 | 2 |
| 6886 | TAL1 | 3 |
| 10891 | PPARGC1A | 4 |
| 440270 | GOLGA8B | 2 |
| 5288 | PIK3C2G | 8 |
| 57096 | RPGRIP1 | 2 |
| 2044 | EPHA5 | 2 |
| 5287 | PIK3C2B | 3 |
| 4629 | MYH11 | 3 |
| 1608 | DGKG | 2 |
| 2178 | FANCE | 1 |
| 83732 | RIOK1 | 2 |
| 57699 | CPNE5 | 3 |
| 654790 | PCP4L1 | 3 |
| 27151 | CPAMD8 | 2 |
| 5602 | MAPK10 | 2 |
| 2892 | GRIA3 | 5 |
| 1436 | CSF1R | 3 |
| 1795 | DOCK3 | 2 |
| 4486 | MST1R | 3 |
| 5624 | PROC | 2 |
| 5970 | RELA | 2 |
| 578 | BAK1 | 3 |
Gene in drug-gene network: Network Plot
Models in BRD6368
CLASSFICATION
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Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.