TNKS2

Summary:

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nametankyrase 2
OMIM IDMIM:607128
Ensembl IDEnsembl:ENSG00000107854
HGNC IDHGNC:HGNC:15677
PHARMGKB IDPA38019
Map Location10q23.32

Gene Categories:

DRUGGABLE GENOME

GO terms in TNKS2


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Term Type
Evidence Type
GO Term ID
GO Des.
CC IEA GO:0000139 Golgi membrane
CC IDA GO:0000242 pericentriolar material
CC IC GO:0000784 nuclear chromosome, telomeric region
CC IBA GO:0005634 nucleus
CC IDA GO:0005634 nucleus
CC IDA GO:0005635 nuclear envelope
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Gene expression in normal tissue: TNKS2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in TNKS2


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Database
Pathway ID
Pathway Des.
wikipathways WP3645 NAD+ biosynthetic pathways
reactome R-HSA-1257604 PIP3 activates AKT signaling
reactome R-HSA-162582 Signal Transduction
reactome R-HSA-1643685 Disease
reactome R-HSA-195721 Signaling by WNT
reactome R-HSA-201681 TCF dependent signaling in response to WNT
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD512 nutlin 3 3
iGMDRD307 Manumycin A 3
iGMDRD405 PIK-75 3
iGMDRD424 Tamatinib 3
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in TNKS2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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