MAPK15
Summary:
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| mitogen-activated protein kinase 15 | Ensembl:ENSG00000181085 | HGNC:HGNC:24667 | PA142671478 | - |
GO terms in MAPK15
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| BP | IEA | GO:0000165 | MAPK cascade |
| BP | IMP | GO:0003400 | regulation of COPII vesicle coating |
| BP | IDA | GO:0006974 | cellular response to DNA damage stimulus |
| BP | IMP | GO:0007029 | endoplasmic reticulum organization |
| BP | IDA | GO:0008284 | positive regulation of cell proliferation |
| BP | IMP | GO:0008284 | positive regulation of cell proliferation |
| BP | IBA | GO:0010468 | regulation of gene expression |
| BP | IDA | GO:0010506 | regulation of autophagy |
| BP | IMP | GO:0030336 | negative regulation of cell migration |
| BP | IDA | GO:0032212 | positive regulation of telomere maintenance via telomerase |
| BP | IMP | GO:0032212 | positive regulation of telomere maintenance via telomerase |
| BP | IBA | GO:0035556 | intracellular signal transduction |
| BP | IDA | GO:0046777 | protein autophosphorylation |
| BP | IDA | GO:0051973 | positive regulation of telomerase activity |
| BP | IMP | GO:0051973 | positive regulation of telomerase activity |
| BP | IDA | GO:0090494 | dopamine uptake |
| BP | IMP | GO:1902017 | regulation of cilium assembly |
| BP | ISS | GO:1902017 | regulation of cilium assembly |
| BP | IDA | GO:1904355 | positive regulation of telomere capping |
| BP | IMP | GO:1904355 | positive regulation of telomere capping |
| BP | IMP | GO:1904491 | protein localization to ciliary transition zone |
| BP | IEA | GO:1905188 | positive regulation of metaphase/anaphase transition of meiosis I |
| BP | IEA | GO:1905832 | positive regulation of spindle assembly |
| CC | NAS | GO:0005576 | extracellular region |
| CC | NAS | GO:0005622 | intracellular |
| CC | IBA | GO:0005634 | nucleus |
| CC | IDA | GO:0005634 | nucleus |
| CC | IBA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005737 | cytoplasm |
| CC | IDA | GO:0005776 | autophagosome |
| CC | IDA | GO:0005794 | Golgi apparatus |
| CC | IDA | GO:0005814 | centriole |
| CC | IDA | GO:0005911 | cell-cell junction |
| CC | IDA | GO:0005930 | axoneme |
| CC | IDA | GO:0036064 | ciliary basal body |
| CC | IEA | GO:0072687 | meiotic spindle |
| MF | IDA | GO:0003682 | chromatin binding |
| MF | IDA | GO:0004672 | protein kinase activity |
| MF | IBA | GO:0004707 | MAP kinase activity |
| MF | IDA | GO:0004707 | MAP kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IDA | GO:0016301 | kinase activity |
| MF | NAS | GO:0017124 | SH3 domain binding |
Gene expression in normal tissue: MAPK15
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in MAPK15
| Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04657 | IL-17 signaling pathway - Homo sapiens (human) |
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD584 | VER 155008 | 2 |
| iGMDRD546 | BMS-754807 | 3 |
| iGMDRD427 | ABT737 | 1 |
| iGMDRD424 | Tamatinib | 3 |
| iGMDRD781 | Sirolimus | 5 |
| iGMDRD523 | Cyanoquinoline, 11 | 5 |
| iGMDRD61 | Kinetin riboside | 2 |
| iGMDRD6 | AM-580 | 2 |
| iGMDRD870 | BRD63610 | 3 |
| iGMDRD267 | Oligomycin A | 2 |
| iGMDRD885 | Compound 110 | 3 |
| iGMDRD481 | Dactolisib | 4 |
| iGMDRD318 | PAC-1 | 3 |
| iGMDRD226 | ML006 | 2 |
| iGMDRD399 | Selumetinib | 3 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD367 | Ro 28-1675 | 3 |
| iGMDRD871 | BRD6368 | 2 |
| iGMDRD888 | Compound 44 | 2 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD300 | Tozasertib | 2 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD82 | Quiflapon | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in MAPK15
CLASSFICATION
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