SEARCH

HOME / SEARCH / Ro 28-1675

iGMDRD367

Canonical SMILES: CS(=O)(=O)C1=CC=C(C=C1)C(CC2CCCC2)C(=O)NC3=NC=CS3

InChI: InChI=1S/C18H22N2O3S2/c1-25(22,23)15-8-6-14(7-9-15)16(12-13-4-2-3-5-13)17(21)20-18-19-10-11-24-18/h6-11,13,16H,2-5,12H2,1H3,(H,19,20,21)/t16-/m1/s1

InChI Key: NEQSWPCDHDQINX-MRXNPFEDSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Ro 28-1675	9886090	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
5027	P2RX7	3
10641	NPRL2	3
6581	SLC22A3	2
132	ADK	3
7750	ZMYM2	2
4627	MYH9	2
8929	PHOX2B	3
1520	CTSS	3
4750	NEK1	3
5295	PIK3R1	2
2100	ESR2	3
80070	ADAMTS20	4
3939	LDHA	3
25778	DSTYK	2
5079	PAX5	3
9891	NUAK1	3
4170	MCL1	2
23213	SULF1	2
5218	CDK14	3
7253	TSHR	5
6318	SERPINB4	3
9816	URB2	2
7048	TGFBR2	3
31	ACACA	2
1602	DACH1	2
5966	REL	2
3604	TNFRSF9	3
8295	TRRAP	2
11122	PTPRT	1
55351	STK32B	2
5605	MAP2K2	3
54567	DLL4	2
342977	NANOS3	3
152137	CCDC50	2
3621	ING1	2
8549	LGR5	3
4300	MLLT3	2
22806	IKZF3	3
2242	FES	6
7416	VDAC1	3
80351	TNKS2	3
6733	SRPK2	6
5330	PLCB2	3
114548	NLRP3	2
10217	CTDSPL	5
83990	BRIP1	2
6928	HNF1B	5
83931	STK40	2
287015	TRIM42	2
23191	CYFIP1	3
338322	NLRP10	3
783	CACNB2	2
25989	ULK3	3
8859	STK19	3
54437	SEMA5B	3
3685	ITGAV	2
3667	IRS1	3
139285	AMER1	2
8148	TAF15	6
2521	FUS	3
5924	RASGRF2	1
4058	LTK	3
5289	PIK3C3	3
2272	FHIT	4
2066	ERBB4	3
5327	PLAT	3
51517	NCKIPSD	3
2201	FBN2	6
1029	CDKN2A	2
9794	MAML1	2
58508	KMT2C	2
7157	TP53	1
79058	ASPSCR1	3
6794	STK11	1
7869	SEMA3B	2
225689	MAPK15	3
9639	ARHGEF10	2
1019	CDK4	1
1045	CDX2	1
105	ADARB2	2
55034	MOCOS	3
55437	STRADB	2
7038	TG	5
369	ARAF	5
57591	MRTFA	3
5650	KLK7	2
80205	CHD9	1
57578	UNC79	2
4026	LPP	3
8997	KALRN	2
4437	MSH3	4
23269	MGA	3
256536	TCERG1L	2
285220	EPHA6	2
546	ATRX	2
3417	IDH1	3
5297	PI4KA	3
64840	PORCN	3
8216	LZTR1	1
9972	NUP153	2
50615	IL21R	2
5290	PIK3CA	3
92335	STRADA	3
1000	CDH2	1
26524	LATS2	5
4803	NGF	2
3065	HDAC1	2
90956	ADCK2	3
1326	MAP3K8	3
894	CCND2	1
5462	POU5F1B	3
375056	MIA3	2
10971	YWHAQ	3
91754	NEK9	3
56924	PAK6	3
10186	LHFPL6	5
673	BRAF	1
988	CDC5L	3
4863	NPAT	3
57538	ALPK3	3
8924	HERC2	2
120892	LRRK2	2
6095	RORA	2
8626	TP63	3
8178	ELL	3
5378	PMS1	3
23396	PIP5K1C	2
23742	NPAP1	2
23049	SMG1	2
10010	TANK	2
23476	BRD4	3
7030	TFE3	3
5595	MAPK3	2
29959	NRBP1	2
8648	NCOA1	3
79012	CAMKV	2
221895	JAZF1	2
84930	MASTL	2
282974	STK32C	2
10595	ERN2	2
83417	FCRL4	3
81608	FIP1L1	3
2690	GHR	5
9021	SOCS3	3
10111	RAD50	1
54101	RIPK4	3
6093	ROCK1	3
3579	CXCR2	3
5587	PRKD1	2
1719	DHFR	4
10734	STAG3	3
5170	PDPK1	3
3717	JAK2	3
1030	CDKN2B	2
80216	ALPK1	1
444	ASPH	2
11076	TPPP	3
5087	PBX1	3
5925	RB1	2
4302	MLLT6	3
4638	MYLK	2
197259	MLKL	2
3488	IGFBP5	2
4915	NTRK2	3
4763	NF1	1
9625	AATK	2
4591	TRIM37	2
23031	MAST3	2
4629	MYH11	3
23683	PRKD3	3
6868	ADAM17	1
1499	CTNNB1	1
2892	GRIA3	3
2904	GRIN2B	3
5970	RELA	2
26206	SPAG8	1
5590	PRKCZ	3

Gene in drug-gene network: Network Plot

Models in Ro 28-1675

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.