SEMA3B
Summary: The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
Namesemaphorin 3B OMIM IDMIM:601281 Ensembl IDEnsembl:ENSG00000012171 HGNC IDHGNC:HGNC:10724 PHARMGKB IDPA35646 Map Location3p21.31 | |||||
GO terms in SEMA3B
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | IBA | GO:0030215 | semaphorin receptor binding |
| MF | IBA | GO:0038191 | neuropilin binding |
| MF | IBA | GO:0045499 | chemorepellent activity |
| MF | TAS | GO:0045499 | chemorepellent activity |
| CC | IBA | GO:0005615 | extracellular space |
| CC | IEA | GO:0005783 | endoplasmic reticulum |
Gene expression in normal tissue: SEMA3B
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in SEMA3B
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in SEMA3B
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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