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iGMDRD246

Canonical SMILES: CCOC(=O)C1=C(SC2=C1CC(NC2(C)C)(C)C)NC(=O)C3=CC=C(S3)[N+](=O)[O-]

InChI: InChI=1S/C19H23N3O5S2/c1-6-27-17(24)13-10-9-18(2,3)21-19(4,5)14(10)29-16(13)20-15(23)11-7-8-12(28-11)22(25)26/h7-8,21H,6,9H2,1-5H3,(H,20,23)

InChI Key: DWGSXNATVAGHKZ-UHFFFAOYSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
NPC26	3465540	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
331	XIAP	3
1105	CHD1	4
27125	AFF4	3
7514	XPO1	1
8999	CDKL2	5
8019	BRD3	2
10903	MTMR11	5
79848	CSPP1	2
10641	NPRL2	1
6491	STIL	2
8444	DYRK3	3
21	ABCA3	3
3383	ICAM1	4
8915	BCL10	2
8476	CDC42BPA	2
7750	ZMYM2	3
2986	GUCY2F	2
2956	MSH6	2
4303	FOXO4	2
57679	ALS2	6
57554	LRRC7	2
7272	TTK	2
8289	ARID1A	3
8573	CASK	3
5934	RBL2	2
25778	DSTYK	3
6938	TCF12	3
2475	MTOR	4
4036	LRP2	3
10395	DLC1	2
5133	PDCD1	2
3069	HDLBP	2
11116	FGFR1OP	5
7444	VRK2	1
6657	SOX2	3
390502	SERPINA2	2
64783	RBM15	2
51684	SUFU	3
57580	PREX1	1
10892	MALT1	1
23235	SIK2	3
1786	DNMT1	1
23213	SULF1	3
3066	HDAC2	5
10142	AKAP9	2
23310	NCAPD3	3
6732	SRPK1	2
2241	FER	3
341676	NEK5	2
22821	RASA3	2
7048	TGFBR2	3
577	ADGRB3	1
1387	CREBBP	2
7555	CNBP	3
2043	EPHA4	2
5467	PPARD	2
5788	PTPRC	3
31	ACACA	2
10178	TENM1	2
51755	CDK12	3
3604	TNFRSF9	2
8295	TRRAP	2
2977	GUCY1A2	3
10438	C1D	4
27148	STK36	1
5159	PDGFRB	5
10215	OLIG2	3
4851	NOTCH1	1
5314	PKHD1	3
139378	ADGRG4	2
145264	SERPINA12	3
2033	EP300	7
6927	HNF1A	2
54567	DLL4	2
55728	N4BP2	2
54477	PLEKHA5	4
57670	KIAA1549	3
440279	UNC13C	5
340156	MYLK4	1
4301	AFDN	4
84033	OBSCN	5
342977	NANOS3	4
1540	CYLD	2
131096	KCNH8	3
23012	STK38L	3
8852	AKAP4	3
3556	IL1RAP	2
26353	HSPB8	3
22806	IKZF3	1
80351	TNKS2	4
1437	CSF2	3
8313	AXIN2	3
2042	EPHA3	2
2260	FGFR1	6
23255	MTCL1	2
730249	ACOD1	3
10188	TNK2	2
9636	ISG15	3
83990	BRIP1	3
269	AMHR2	2
83931	STK40	4
55681	SCYL2	3
4982	TNFRSF11B	4
375449	MAST4	2
85443	DCLK3	2
287015	TRIM42	3
65217	PCDH15	3
8395	PIP5K1B	3
286826	LIN9	3
7486	WRN	2
23191	CYFIP1	6
1456	CSNK1G3	2
6416	MAP2K4	3
9759	HDAC4	7
1452	CSNK1A1	2
57510	XPO5	2
6793	STK10	3
6098	ROS1	3
2778	GNAS	3
3667	IRS1	4
80243	PREX2	3
472	ATM	2
8945	BTRC	3
5229	PGGT1B	3
575	ADGRB1	4
4058	LTK	2
1123	CHN1	2
2272	FHIT	5
2066	ERBB4	3
10413	YAP1	3
2201	FBN2	3
1029	CDKN2A	2
9794	MAML1	8
57523	NYNRIN	2
2868	GRK4	2
11143	KAT7	2
28514	DLL1	6
58508	KMT2C	3
7157	TP53	4
6092	ROBO2	2
4173	MCM4	4
7869	SEMA3B	2
836	CASP3	2
114788	CSMD3	4
2263	FGFR2	2
7249	TSC2	2
11213	IRAK3	3
84075	FSCB	2
9967	THRAP3	4
4921	DDR2	3
3572	IL6ST	3
6197	RPS6KA3	3
55589	BMP2K	3
65125	WNK1	5
136332	LRGUK	3
4436	MSH2	3
984	CDK11B	3
7175	TPR	3
5871	MAP4K2	6
80205	CHD9	6
23365	ARHGEF12	6
57578	UNC79	2
8997	KALRN	3
23269	MGA	5
3643	INSR	3
23469	PHF3	2
170692	ADAMTS18	2
7204	TRIO	2
78989	COLEC11	2
23373	CRTC1	3
9448	MAP4K4	3
285220	EPHA6	3
3426	CFI	6
3417	IDH1	6
5606	MAP2K3	3
5297	PI4KA	3
54756	IL17RD	3
7786	MAP3K12	6
56997	COQ8A	3
3702	ITK	4
3239	HOXD13	3
2187	FANCB	3
84823	LMNB2	1
3562	IL3	5
3720	JARID2	4
5034	P4HB	5
253260	RICTOR	2
2318	FLNC	2
675	BRCA2	3
26166	RGS22	4
7075	TIE1	4
744	MPPED2	3
157680	VPS13B	2
841	CASP8	2
11064	CNTRL	2
3308	HSPA4	3
5789	PTPRD	2
10461	MERTK	7
7297	TYK2	1
26278	SACS	2
894	CCND2	3
1440	CSF3	3
6776	STAT5A	3
51265	CDKL3	3
6446	SGK1	3
375056	MIA3	4
93627	TBCK	4
137872	ADHFE1	3
27330	RPS6KA6	6
6872	TAF1	6
57082	KNL1	3
1213	CLTC	3
4790	NFKB1	9
22976	PAXIP1	4
4863	NPAT	6
780	DDR1	2
8924	HERC2	3
2078	ERG	3
120892	LRRK2	4
867	CBL	4
146057	TTBK2	3
5205	ATP8B1	2
7468	NSD2	5
460	ASTN1	2
9451	EIF2AK3	2
11262	SP140	2
8491	MAP4K3	3
8312	AXIN1	5
1806	DPYD	3
667	DST	4
3554	IL1R1	3
2897	GRIK1	3
1950	EGF	2
1676	DFFA	3
8301	PICALM	3
7273	TTN	2
7465	WEE1	1
7059	THBS3	3
85415	RHPN2	3
23389	MED13L	2
2277	VEGFD	2
23411	SIRT1	3
8648	NCOA1	3
55561	CDC42BPG	3
23305	ACSL6	3
10595	ERN2	2
558	AXL	2
4619	MYH1	2
3985	LIMK2	3
57680	CHD8	2
2869	GRK5	2
5923	RASGRF1	3
1399	CRKL	3
8031	NCOA4	3
9223	MAGI1	3
53353	LRP1B	2
55289	ACOXL	1
1281	COL3A1	3
9659	PDE4DIP	3
63976	PRDM16	2
54101	RIPK4	3
131890	GRK7	2
5927	KDM5A	2
5587	PRKD1	1
5589	PRKCSH	2
5170	PDPK1	2
2321	FLT1	3
57448	BIRC6	3
2131	EXT1	3
23139	MAST2	1
2157	F8	2
3709	ITPR2	2
6778	STAT6	5
4221	MEN1	1
4067	LYN	2
3552	IL1A	1
2719	GPC3	5
80216	ALPK1	1
3977	LIFR	2
444	ASPH	2
182	JAG1	3
2122	MECOM	3
3815	KIT	3
4893	NRAS	1
8661	EIF3A	5
7403	KDM6A	3
1234	CCR5	2
7508	XPC	1
4302	MLLT6	3
4638	MYLK	7
197259	MLKL	2
5586	PKN2	3
7040	TGFB1	5
2011	MARK2	2
10494	STK25	3
4299	AFF1	2
581	BAX	3
9625	AATK	3
57096	RPGRIP1	3
2280	FKBP1A	3
23683	PRKD3	3
2178	FANCE	2
27255	CNTN6	4
1499	CTNNB1	4
2444	FRK	3
1436	CSF1R	3
4486	MST1R	6
5624	PROC	6
1488	CTBP2	3

Gene in drug-gene network: Network Plot

Models in NPC26

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.