ASTN1
Summary: Astrotactin is a neuronal adhesion molecule required for glial-guided migration of young postmitotic neuroblasts in cortical regions of developing brain, including cerebrum, hippocampus, cerebellum, and olfactory bulb (Fink et al., 1995).[supplied by OMIM, Jun 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| astrotactin 1 | MIM:600904 | Ensembl:ENSG00000152092 | HGNC:HGNC:773 | PA162376961 | 1q25.2 |
GO terms in ASTN1
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | ND | GO:0005575 | cellular_component |
| CC | IEA | GO:0005768 | endosome |
| CC | IEA | GO:0009897 | external side of plasma membrane |
| CC | IEA | GO:0016021 | integral component of membrane |
| CC | IEA | GO:0030136 | clathrin-coated vesicle |
| CC | IEA | GO:0043204 | perikaryon |
| BP | IEA | GO:0001764 | neuron migration |
| BP | IEA | GO:0007158 | neuron cell-cell adhesion |
| BP | IEA | GO:0007626 | locomotory behavior |
Gene expression in normal tissue: ASTN1
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD885 | Compound 110 | 2 |
| iGMDRD294 | Batimastat | 2 |
| iGMDRD188 | Piperlongumine | 5 |
| iGMDRD577 | BIX01294 | 1 |
| iGMDRD506 | Fedratinib | 1 |
| iGMDRD562 | Navitoclax | 2 |
| iGMDRD369 | TGX-115 | 3 |
| iGMDRD268 | Cerulenin | 2 |
| iGMDRD889 | Compound 7d-cis | 4 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD670 | ML 210 | 2 |
| iGMDRD427 | ABT737 | 3 |
| iGMDRD446 | LY 2183240 | 3 |
| iGMDRD201 | SKI II | 2 |
| iGMDRD297 | Austocystin D | 2 |
| iGMDRD634 | SCHEMBL2608041 | 5 |
| iGMDRD103 | SN-38 | 3 |
| iGMDRD202 | Curcumin | 2 |
| iGMDRD137 | Indisulam | 3 |
| iGMDRD158 | NSC141540 | 5 |
| iGMDRD105 | Triptolide | 2 |
| iGMDRD68 | Paclitaxel | 1 |
| iGMDRD77 | Itraconazole | 2 |
| iGMDRD286 | Nsc 632839 | 3 |
| iGMDRD872 | BRD7137 | 3 |
| iGMDRD886 | Compound 1541A | 3 |
| iGMDRD246 | NPC26 | 2 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD307 | Manumycin A | 3 |
| iGMDRD148 | Pifithrin-mu | 3 |
| iGMDRD79 | Gemcitabine | 2 |
| iGMDRD237 | ABT-751 | 2 |
| iGMDRD211 | (1S,3R)-RSL3 | 3 |
| iGMDRD123 | Isoevodiamine | 2 |
| iGMDRD177 | Teniposide | 3 |
| iGMDRD154 | NSC23766 | 2 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in ASTN1
CLASSFICATION
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