iGMDRD1008


Standard NameDrug Status
SR-II-138AAlone

Drug Targets:

EIF4A2EIF4EEIF4G1

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot


Gene IDGene NameModel Num.
331XIAP2
1105CHD12
7514XPO11
8999CDKL22
5296PIK3R23
5027P2RX72
10903MTMR112
10221TRIB13
1464CSPG42
7128TNFAIP33
5261PHKG22
9261MAPKAPK21
5933RBL16
8476CDC42BPA2
11183MAP4K53
2986GUCY2F2
79947DHDDS1
5546PRCC3
2956MSH61
7171TPM43
150465TTL3
57554LRRC72
1969EPHA22
7272TTK2
3845KRAS2
4750NEK12
23552CDK202
23097CDK193
80070ADAMTS201
9475ROCK22
7764ZNF2173
10395DLC12
353345GPR1412
5133PDCD12
3069HDLBP1
83481EPPK11
7444VRK23
390502SERPINA23
64783RBM151
57580PREX11
10892MALT14
4771NF23
4313MMP22
3320HSP90AA12
3066HDAC22
10142AKAP92
22853LMTK22
7253TSHR1
7098TLR33
2241FER2
1404HAPLN12
9816URB21
1387CREBBP6
2043EPHA43
5579PRKCB4
11200CHEK23
1602DACH12
5074PAWR3
3604TNFRSF93
8295TRRAP2
10438C1D1
7173TPO1
51512GTSE16
89910UBE3B3
55294FBXW71
974CD79B3
9578CDC42BPB2
54477PLEKHA53
57670KIAA15493
22861NLRP12
440279UNC13C5
4610MYCL10
4301AFDN2
84033OBSCN3
342977NANOS32
8600TNFSF113
169436STKLD13
3556IL1RAP1
7416VDAC13
5468PPARG4
80351TNKS23
8313AXIN23
1050CEBPA3
2260FGFR13
730249ACOD13
10188TNK23
10298PAK43
2736GLI22
83990BRIP16
51804SIX42
269AMHR22
7424VEGFC3
55681SCYL22
238ALK2
375449MAST42
22858ICK4
2064ERBB23
6850SYK1
65217PCDH153
6663SOX101
9020MAP3K141
7486WRN2
92ACVR2A2
1452CSNK1A15
25989ULK32
1973EIF4A13
50488MINK16
8859STK196
6098ROS13
9472AKAP62
8515ITGA102
2778GNAS2
130497OSR14
6917TCEA13
80243PREX23
472ATM1
8945BTRC2
4605MYBL23
575ADGRB12
4087SMAD22
2734GLG13
9096TBX183
9564BCAR13
4058LTK2
6792CDKL52
7533YWHAH2
5289PIK3C31
5450POU2AF13
898CCNE13
7681MKRN32
9319TRIP131
2201FBN22
1029CDKN2A1
7184HSP90B12
157753TMEM743
2868GRK41
5834PYGB1
58508KMT2C2
7157TP534
2099ESR13
4173MCM42
2322FLT32
25836NIPBL6
7869SEMA3B2
8218CLTCL15
5910RAP1GDS16
4086SMAD11
225689MAPK153
7249TSC23
1019CDK41
65243ZFP69B10
863CBFA2T33
8874ARHGEF71
1555CYP2B63
55034MOCOS3
4921DDR23
3572IL6ST3
9965FGF191
57105CYSLTR23
136332LRGUK5
4436MSH22
80205CHD91
2081ERN16
2071ERCC33
3643INSR3
4089SMAD41
9448MAP4K43
285220EPHA62
546ATRX2
3426CFI2
3417IDH13
5297PI4KA1
2047EPHB11
10926DBF42
340533NEXMIF3
8216LZTR11
3562IL33
92335STRADA1
3720JARID22
4293MAP3K93
26524LATS21
5045FURIN5
675BRCA22
7075TIE15
841CASP82
3065HDAC13
4609MYC3
2624GATA23
5155PDGFB3
10461MERTK3
26278SACS2
1440CSF33
833CARS6
375056MIA32
203102ADAM322
7153TOP2A2
1213CLTC1
84879MFSD2A10
3315HSPB13
23532PRAME2
83452RAB33B2
8924HERC22
120892LRRK23
11126CD1603
29844TFPT1
8029CUBN3
8626TP632
9113LATS13
460ASTN13
7849PAX83
9321TRIP112
1977EIF4E1
8621CDK133
23049SMG13
55521TRIM363
208AKT23
5595MAPK33
1869E2F16
667DST2
3554IL1R12
352909DNAAF33
6146RPL222
2648KAT2A1
177AGER3
8301PICALM3
3899AFF33
7273TTN2
1445CSK3
1018CDK33
79834PEAK12
7465WEE13
7454WAS3
85415RHPN23
203447NRK3
2277VEGFD3
29959NRBP12
79012CAMKV2
2046EPHA82
221895JAZF12
84930MASTL2
8805TRIM243
22843PPM1E1
2353FOS2
51151SLC45A23
558AXL3
7248TSC12
2932GSK3B3
5923RASGRF13
10111RAD501
55289ACOXL3
1281COL3A12
9659PDE4DIP3
3557IL1RN3
6760SS181
5927KDM5A6
1385CREB13
5111PCNA1
2131EXT16
57007ACKR33
3717JAK23
23139MAST25
7227TRPS13
3709ITPR27
6778STAT64
4067LYN3
3984LIMK13
2719GPC33
80216ALPK13
5915RARB3
4261CIITA3
170685NUDT101
8536CAMK13
2122MECOM3
5054SERPINE11
5925RB16
1209CLPTM12
5324PLAG13
862RUNX1T12
7403KDM6A6
9878TOX43
10494STK251
2261FGFR33
3237HOXD111
138474TAF1L3
10891PPARGC1A1
5288PIK3C2G2
94ACVRL11
30811HUNK3
3679ITGA73
1608DGKG5
7294TXK1
6868ADAM171
27255CNTN62
3895KTN13
2892GRIA33
167359NIM1K2

Gene in drug-gene network: Network Plot

Models in SR-II-138A

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