NEXMIF
Summary: An inversion on the X chromosome which disrupts this gene and a G-protein coupled purinergic receptor gene located in the pseudoautosomal region of the X chromosome has been linked to X linked cognitive disability.[provided by RefSeq, Mar 2009].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| neurite extension and migration factor | MIM:300524 | Ensembl:ENSG00000050030 | HGNC:HGNC:29433 | PA162393214 | Xq13.3 |
Gene Categories:
DNA REPAIRGO terms in NEXMIF
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0005737 | cytoplasm |
| BP | IBA | GO:0001953 | negative regulation of cell-matrix adhesion |
| BP | IEA | GO:0001953 | negative regulation of cell-matrix adhesion |
| BP | IBA | GO:0006261 | DNA-dependent DNA replication |
| BP | IEA | GO:0006351 | transcription, DNA-templated |
| BP | IEA | GO:0006355 | regulation of transcription, DNA-templated |
| BP | IBA | GO:0033629 | negative regulation of cell adhesion mediated by integrin |
| BP | IEA | GO:0033629 | negative regulation of cell adhesion mediated by integrin |
| BP | IBA | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin |
| BP | IEA | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin |
| BP | IBA | GO:2001223 | negative regulation of neuron migration |
| BP | IEA | GO:2001223 | negative regulation of neuron migration |
Gene expression in normal tissue: NEXMIF
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NEXMIF
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD451 | Serdemetan | 2 |
| iGMDRD322 | FK 866 | 2 |
| iGMDRD524 | ISX-9 | 3 |
| iGMDRD353 | PD0325901 | 1 |
| iGMDRD23 | Gossypol | 2 |
| iGMDRD268 | Cerulenin | 1 |
| iGMDRD100 | Zebularine | 3 |
| iGMDRD188 | Piperlongumine | 2 |
| iGMDRD366 | PI-103 | 3 |
| iGMDRD562 | Navitoclax | 2 |
| iGMDRD506 | Fedratinib | 3 |
| iGMDRD662 | JQ-1 | 2 |
| iGMDRD434 | BMS-536924 | 2 |
| iGMDRD289 | Parthenolide | 4 |
| iGMDRD221 | Tamoxifen | 3 |
| iGMDRD207 | Capsaicin | 2 |
| iGMDRD52 | Rotenone | 3 |
| iGMDRD481 | Dactolisib | 3 |
| iGMDRD318 | PAC-1 | 2 |
| iGMDRD103 | SN-38 | 2 |
| iGMDRD945 | ML214 | 1 |
| iGMDRD359 | OSW-1 | 2 |
| iGMDRD85 | Ursolic acid | 1 |
| iGMDRD341 | Triacsin c | 3 |
| iGMDRD61 | Kinetin riboside | 1 |
| iGMDRD560 | MK-2206 | 6 |
| iGMDRD554 | CHEMBL1434137 | 3 |
| iGMDRD84 | Lovastatin acid | 3 |
| iGMDRD1008 | SR-II-138A | 3 |
| iGMDRD512 | nutlin 3 | 6 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NEXMIF
CLASSFICATION
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