iGMDRD945
| Standard Name | Drug Status |
|---|---|
| ML214 | Alone |
Drug-model tissue-cancer distribution: Bubble Plot
Drug-gene pathway enrichments
Drug-gene GO enrichments
Drug-Gene: Aster Plot
| Gene ID | Gene Name | Model Num. |
|---|---|---|
| 331 | XIAP | 2 |
| 27102 | EIF2AK1 | 2 |
| 9833 | MELK | 1 |
| 8999 | CDKL2 | 2 |
| 7074 | TIAM1 | 1 |
| 10460 | TACC3 | 3 |
| 5296 | PIK3R2 | 5 |
| 471 | ATIC | 4 |
| 79848 | CSPP1 | 2 |
| 7837 | PXDN | 5 |
| 79054 | TRPM8 | 3 |
| 6491 | STIL | 2 |
| 2986 | GUCY2F | 2 |
| 57679 | ALS2 | 3 |
| 1588 | CYP19A1 | 3 |
| 57554 | LRRC7 | 3 |
| 9149 | DYRK1B | 6 |
| 7272 | TTK | 4 |
| 1138 | CHRNA5 | 6 |
| 8289 | ARID1A | 2 |
| 80070 | ADAMTS20 | 4 |
| 8573 | CASK | 3 |
| 11193 | WBP4 | 3 |
| 53616 | ADAM22 | 2 |
| 3431 | SP110 | 3 |
| 6938 | TCF12 | 3 |
| 2475 | MTOR | 1 |
| 9263 | STK17A | 6 |
| 5916 | RARG | 3 |
| 4036 | LRP2 | 2 |
| 7764 | ZNF217 | 2 |
| 10395 | DLC1 | 2 |
| 5133 | PDCD1 | 2 |
| 11116 | FGFR1OP | 4 |
| 10320 | IKZF1 | 3 |
| 3209 | HOXA13 | 6 |
| 7444 | VRK2 | 2 |
| 6657 | SOX2 | 3 |
| 390502 | SERPINA2 | 7 |
| 4771 | NF2 | 3 |
| 23235 | SIK2 | 3 |
| 1607 | DGKB | 4 |
| 3694 | ITGB6 | 5 |
| 23213 | SULF1 | 3 |
| 3066 | HDAC2 | 8 |
| 5298 | PI4KB | 3 |
| 8749 | ADAM18 | 3 |
| 2241 | FER | 3 |
| 55534 | MAML3 | 3 |
| 341676 | NEK5 | 3 |
| 22821 | RASA3 | 2 |
| 6455 | SH3GL1 | 3 |
| 1545 | CYP1B1 | 1 |
| 140469 | MYO3B | 3 |
| 54822 | TRPM7 | 2 |
| 943 | TNFRSF8 | 6 |
| 80122 | MAP3K19 | 2 |
| 1387 | CREBBP | 3 |
| 2043 | EPHA4 | 2 |
| 5788 | PTPRC | 2 |
| 31 | ACACA | 3 |
| 51755 | CDK12 | 3 |
| 9070 | ASH2L | 6 |
| 9048 | ARTN | 2 |
| 5533 | PPP3CC | 6 |
| 8558 | CDK10 | 6 |
| 3604 | TNFRSF9 | 2 |
| 8295 | TRRAP | 5 |
| 10438 | C1D | 1 |
| 23617 | TSSK2 | 2 |
| 5899 | RALB | 1 |
| 5166 | PDK4 | 2 |
| 10215 | OLIG2 | 3 |
| 4851 | NOTCH1 | 3 |
| 139378 | ADGRG4 | 8 |
| 145264 | SERPINA12 | 6 |
| 974 | CD79B | 3 |
| 54567 | DLL4 | 2 |
| 55728 | N4BP2 | 3 |
| 25865 | PRKD2 | 6 |
| 1453 | CSNK1D | 6 |
| 7852 | CXCR4 | 3 |
| 54477 | PLEKHA5 | 4 |
| 22861 | NLRP1 | 4 |
| 837 | CASP4 | 6 |
| 4301 | AFDN | 3 |
| 10272 | FSTL3 | 6 |
| 84033 | OBSCN | 1 |
| 256646 | NUTM1 | 3 |
| 1880 | GPR183 | 3 |
| 6418 | SET | 6 |
| 4478 | MSN | 6 |
| 1586 | CYP17A1 | 4 |
| 3714 | JAG2 | 3 |
| 5613 | PRKX | 1 |
| 4300 | MLLT3 | 2 |
| 26353 | HSPB8 | 3 |
| 22984 | PDCD11 | 1 |
| 80351 | TNKS2 | 3 |
| 8313 | AXIN2 | 2 |
| 6091 | ROBO1 | 2 |
| 2042 | EPHA3 | 2 |
| 2260 | FGFR1 | 2 |
| 23255 | MTCL1 | 1 |
| 11169 | WDHD1 | 3 |
| 4216 | MAP3K4 | 3 |
| 6198 | RPS6KB1 | 5 |
| 57761 | TRIB3 | 6 |
| 3303 | HSPA1A | 6 |
| 6928 | HNF1B | 2 |
| 7088 | TLE1 | 1 |
| 27324 | TOX3 | 3 |
| 284217 | LAMA1 | 2 |
| 207 | AKT1 | 7 |
| 55681 | SCYL2 | 3 |
| 4982 | TNFRSF11B | 3 |
| 2045 | EPHA7 | 3 |
| 375449 | MAST4 | 1 |
| 4752 | NEK3 | 3 |
| 22858 | ICK | 1 |
| 94103 | ORMDL3 | 3 |
| 287015 | TRIM42 | 4 |
| 65217 | PCDH15 | 3 |
| 8395 | PIP5K1B | 2 |
| 993 | CDC25A | 3 |
| 286826 | LIN9 | 6 |
| 23191 | CYFIP1 | 3 |
| 4294 | MAP3K10 | 4 |
| 783 | CACNB2 | 2 |
| 6416 | MAP2K4 | 1 |
| 7525 | YES1 | 4 |
| 57510 | XPO5 | 2 |
| 8215 | DVL1P1 | 3 |
| 1973 | EIF4A1 | 3 |
| 1909 | EDNRA | 3 |
| 50488 | MINK1 | 5 |
| 8859 | STK19 | 3 |
| 5568 | PRKACG | 2 |
| 6464 | SHC1 | 3 |
| 659 | BMPR2 | 4 |
| 9472 | AKAP6 | 1 |
| 8515 | ITGA10 | 3 |
| 2778 | GNAS | 3 |
| 80243 | PREX2 | 3 |
| 472 | ATM | 2 |
| 575 | ADGRB1 | 1 |
| 2734 | GLG1 | 6 |
| 84433 | CARD11 | 3 |
| 1123 | CHN1 | 7 |
| 7533 | YWHAH | 3 |
| 2050 | EPHB4 | 3 |
| 904 | CCNT1 | 3 |
| 10413 | YAP1 | 6 |
| 2201 | FBN2 | 3 |
| 7184 | HSP90B1 | 6 |
| 10062 | NR1H3 | 3 |
| 9361 | LONP1 | 6 |
| 5129 | CDK18 | 3 |
| 5336 | PLCG2 | 3 |
| 11143 | KAT7 | 2 |
| 10018 | BCL2L11 | 6 |
| 27347 | STK39 | 1 |
| 58508 | KMT2C | 2 |
| 6092 | ROBO2 | 4 |
| 7704 | ZBTB16 | 2 |
| 4173 | MCM4 | 3 |
| 4602 | MYB | 3 |
| 4855 | NOTCH4 | 1 |
| 6794 | STK11 | 12 |
| 25836 | NIPBL | 3 |
| 7869 | SEMA3B | 1 |
| 960 | CD44 | 4 |
| 3791 | KDR | 3 |
| 836 | CASP3 | 2 |
| 114788 | CSMD3 | 5 |
| 2263 | FGFR2 | 4 |
| 7249 | TSC2 | 2 |
| 11213 | IRAK3 | 3 |
| 9967 | THRAP3 | 2 |
| 85481 | PSKH2 | 6 |
| 5604 | MAP2K1 | 3 |
| 8874 | ARHGEF7 | 4 |
| 1555 | CYP2B6 | 3 |
| 51086 | TNNI3K | 3 |
| 55034 | MOCOS | 2 |
| 10516 | FBLN5 | 1 |
| 5164 | PDK2 | 6 |
| 5600 | MAPK11 | 3 |
| 8893 | EIF2B5 | 6 |
| 4921 | DDR2 | 3 |
| 5077 | PAX3 | 2 |
| 57105 | CYSLTR2 | 3 |
| 652 | BMP4 | 3 |
| 30012 | TLX3 | 6 |
| 5871 | MAP4K2 | 10 |
| 23365 | ARHGEF12 | 1 |
| 8831 | SYNGAP1 | 3 |
| 57578 | UNC79 | 2 |
| 8997 | KALRN | 3 |
| 7994 | KAT6A | 3 |
| 3643 | INSR | 3 |
| 5371 | PML | 3 |
| 23469 | PHF3 | 1 |
| 170692 | ADAMTS18 | 3 |
| 10733 | PLK4 | 3 |
| 835 | CASP2 | 3 |
| 51366 | UBR5 | 1 |
| 3426 | CFI | 2 |
| 5297 | PI4KA | 4 |
| 501 | ALDH7A1 | 3 |
| 7786 | MAP3K12 | 5 |
| 10926 | DBF4 | 4 |
| 56997 | COQ8A | 6 |
| 340533 | NEXMIF | 1 |
| 5578 | PRKCA | 1 |
| 3702 | ITK | 6 |
| 3239 | HOXD13 | 6 |
| 5290 | PIK3CA | 8 |
| 3720 | JARID2 | 3 |
| 5034 | P4HB | 3 |
| 1000 | CDH2 | 2 |
| 5045 | FURIN | 1 |
| 2318 | FLNC | 4 |
| 10565 | ARFGEF1 | 2 |
| 64919 | BCL11B | 6 |
| 2030 | SLC29A1 | 5 |
| 675 | BRCA2 | 4 |
| 26166 | RGS22 | 3 |
| 4803 | NGF | 5 |
| 10155 | TRIM28 | 3 |
| 7075 | TIE1 | 3 |
| 640 | BLK | 4 |
| 4609 | MYC | 1 |
| 64333 | ARHGAP9 | 3 |
| 64750 | SMURF2 | 1 |
| 91 | ACVR1B | 3 |
| 5789 | PTPRD | 3 |
| 1459 | CSNK2A2 | 2 |
| 8013 | NR4A3 | 3 |
| 10461 | MERTK | 9 |
| 7297 | TYK2 | 4 |
| 26278 | SACS | 6 |
| 894 | CCND2 | 3 |
| 6776 | STAT5A | 2 |
| 51265 | CDKL3 | 2 |
| 51701 | NLK | 3 |
| 6446 | SGK1 | 3 |
| 5663 | PSEN1 | 3 |
| 5747 | PTK2 | 2 |
| 8900 | CCNA1 | 1 |
| 23604 | DAPK2 | 3 |
| 7917 | BAG6 | 3 |
| 375056 | MIA3 | 1 |
| 93627 | TBCK | 4 |
| 27330 | RPS6KA6 | 2 |
| 6872 | TAF1 | 2 |
| 4790 | NFKB1 | 3 |
| 84879 | MFSD2A | 6 |
| 988 | CDC5L | 3 |
| 22976 | PAXIP1 | 2 |
| 23532 | PRAME | 6 |
| 4863 | NPAT | 2 |
| 5598 | MAPK7 | 11 |
| 2078 | ERG | 3 |
| 6469 | SHH | 2 |
| 120892 | LRRK2 | 4 |
| 89795 | NAV3 | 4 |
| 65268 | WNK2 | 2 |
| 867 | CBL | 3 |
| 6095 | RORA | 5 |
| 29844 | TFPT | 3 |
| 57507 | ZNF608 | 1 |
| 7468 | NSD2 | 5 |
| 9113 | LATS1 | 2 |
| 4298 | MLLT1 | 3 |
| 5979 | RET | 3 |
| 9451 | EIF2AK3 | 5 |
| 1977 | EIF4E | 6 |
| 11262 | SP140 | 2 |
| 8491 | MAP4K3 | 3 |
| 8621 | CDK13 | 3 |
| 3654 | IRAK1 | 6 |
| 23742 | NPAP1 | 1 |
| 10010 | TANK | 5 |
| 8312 | AXIN1 | 5 |
| 10752 | CHL1 | 2 |
| 1487 | CTBP1 | 2 |
| 5595 | MAPK3 | 2 |
| 140609 | NEK7 | 6 |
| 4004 | LMO1 | 3 |
| 284086 | NEK8 | 1 |
| 53836 | GPR87 | 3 |
| 1613 | DAPK3 | 6 |
| 5305 | PIP4K2A | 1 |
| 2897 | GRIK1 | 3 |
| 4317 | MMP8 | 3 |
| 2188 | FANCF | 6 |
| 2264 | FGFR4 | 2 |
| 3678 | ITGA5 | 4 |
| 1676 | DFFA | 3 |
| 9344 | TAOK2 | 3 |
| 8301 | PICALM | 3 |
| 3899 | AFF3 | 3 |
| 4055 | LTBR | 5 |
| 7273 | TTN | 2 |
| 1445 | CSK | 3 |
| 91807 | MYLK3 | 1 |
| 5582 | PRKCG | 4 |
| 7036 | TFR2 | 6 |
| 23389 | MED13L | 2 |
| 8028 | MLLT10 | 2 |
| 53904 | MYO3A | 3 |
| 9372 | ZFYVE9 | 3 |
| 2046 | EPHA8 | 1 |
| 7150 | TOP1 | 2 |
| 8821 | INPP4B | 3 |
| 84930 | MASTL | 2 |
| 8394 | PIP5K1A | 6 |
| 3207 | HOXA11 | 6 |
| 1662 | DDX10 | 3 |
| 10595 | ERN2 | 5 |
| 344905 | ATP13A5 | 2 |
| 5562 | PRKAA1 | 3 |
| 1399 | CRKL | 3 |
| 2690 | GHR | 3 |
| 2041 | EPHA1 | 3 |
| 2317 | FLNB | 3 |
| 8031 | NCOA4 | 3 |
| 100124696 | TEC | 3 |
| 6790 | AURKA | 6 |
| 1789 | DNMT3B | 2 |
| 55289 | ACOXL | 3 |
| 7094 | TLN1 | 3 |
| 5609 | MAP2K7 | 1 |
| 152110 | NEK10 | 3 |
| 2185 | PTK2B | 3 |
| 63976 | PRDM16 | 5 |
| 131890 | GRK7 | 1 |
| 2194 | FASN | 3 |
| 5927 | KDM5A | 5 |
| 5587 | PRKD1 | 1 |
| 6196 | RPS6KA2 | 3 |
| 57448 | BIRC6 | 6 |
| 5681 | PSKH1 | 3 |
| 3717 | JAK2 | 3 |
| 2157 | F8 | 3 |
| 57147 | SCYL3 | 3 |
| 6778 | STAT6 | 4 |
| 5603 | MAPK13 | 5 |
| 3516 | RBPJ | 1 |
| 6777 | STAT5B | 3 |
| 80216 | ALPK1 | 3 |
| 3977 | LIFR | 2 |
| 330 | BIRC3 | 6 |
| 4261 | CIITA | 2 |
| 1455 | CSNK1G2 | 8 |
| 11076 | TPPP | 2 |
| 7046 | TGFBR1 | 4 |
| 80781 | COL18A1 | 5 |
| 2122 | MECOM | 3 |
| 3662 | IRF4 | 3 |
| 51167 | CYB5R4 | 2 |
| 1760 | DMPK | 1 |
| 5087 | PBX1 | 4 |
| 3815 | KIT | 6 |
| 4217 | MAP3K5 | 1 |
| 7113 | TMPRSS2 | 8 |
| 7069 | THRSP | 6 |
| 63923 | TNN | 1 |
| 25 | ABL1 | 6 |
| 7403 | KDM6A | 2 |
| 7508 | XPC | 3 |
| 4615 | MYD88 | 3 |
| 4638 | MYLK | 3 |
| 5586 | PKN2 | 3 |
| 4205 | MEF2A | 2 |
| 7040 | TGFB1 | 6 |
| 30849 | PIK3R4 | 1 |
| 55959 | SULF2 | 2 |
| 10494 | STK25 | 3 |
| 4299 | AFF1 | 2 |
| 23072 | HECW1 | 1 |
| 84197 | POMK | 3 |
| 8711 | TNK1 | 4 |
| 156 | GRK2 | 2 |
| 4763 | NF1 | 2 |
| 57697 | FANCM | 3 |
| 5260 | PHKG1 | 3 |
| 55791 | LRIF1 | 1 |
| 9625 | AATK | 3 |
| 4613 | MYCN | 2 |
| 57096 | RPGRIP1 | 3 |
| 2044 | EPHA5 | 2 |
| 3110 | MNX1 | 6 |
| 4629 | MYH11 | 3 |
| 81788 | NUAK2 | 3 |
| 3265 | HRAS | 6 |
| 699 | BUB1 | 2 |
| 2178 | FANCE | 2 |
| 27255 | CNTN6 | 8 |
| 57699 | CPNE5 | 3 |
| 29110 | TBK1 | 1 |
| 5885 | RAD21 | 1 |
| 3440 | IFNA2 | 2 |
| 5602 | MAPK10 | 5 |
| 2892 | GRIA3 | 3 |
| 4486 | MST1R | 6 |
| 1488 | CTBP2 | 3 |
Gene in drug-gene network: Network Plot
Models in ML214
CLASSFICATION
Copyright © 2018 Modellab | All Rights Reserved
Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.