NEK7
Summary: NIMA-related kinases share high amino acid sequence identity with the gene product of the Aspergillus nidulans 'never in mitosis A' gene, which controls initiation of mitosis.[supplied by OMIM, Jul 2002].
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Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
OMIM IDMIM:606848 Ensembl IDEnsembl:ENSG00000151414 HGNC IDHGNC:HGNC:13386 PHARMGKB IDPA31551 Map Location1q31.3 | |||||
GO terms in NEK7
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Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| MF | ISS | GO:0004674 | protein serine/threonine kinase activity |
| MF | IPI | GO:0005515 | protein binding |
| MF | IEA | GO:0005524 | ATP binding |
| MF | IEA | GO:0046872 | metal ion binding |
| CC | IEA | GO:0000922 | spindle pole |
| CC | IDA | GO:0005654 | nucleoplasm |
Gene expression in normal tissue: NEK7
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in NEK7
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Database | Pathway ID | Pathway Des. |
|---|---|---|
| kegg | hsa04621 | NOD-like receptor signaling pathway - Homo sapiens (human) |
| reactome | R-HSA-1640170 | Cell Cycle |
| reactome | R-HSA-2980766 | Nuclear Envelope Breakdown |
| reactome | R-HSA-2980767 | Activation of NIMA Kinases NEK9, NEK6, NEK7 |
| reactome | R-HSA-3301854 | Nuclear Pore Complex (NPC) Disassembly |
| reactome | R-HSA-68875 | Mitotic Prophase |
Gene-Drug: Aster Plot
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in NEK7
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Model | Level | Reference ID | Tissue | Cancer | Drug | Clinical Response | Source | |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||
CLASSFICATION
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