IFNA2

Summary: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Use of the recombinant form of this protein has been shown to be effective in reducing the symptoms and duration of the common cold. [provided by RefSeq, Jun 2011].

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Name
OMIM ID
Ensembl ID
HGNC ID
PHARMGKB ID
Map Location
Nameinterferon alpha 2
OMIM IDMIM:147562
Ensembl IDEnsembl:ENSG00000188379
HGNC IDHGNC:HGNC:5423
PHARMGKB IDPA29662
Map Location9p21.3

Gene Categories:

DRUGGABLE GENOME

GO terms in IFNA2


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Term Type
Evidence Type
GO Term ID
GO Des.
MF IBA GO:0005125 cytokine activity
MF IBA GO:0005132 type I interferon receptor binding
MF TAS GO:0005132 type I interferon receptor binding
MF IPI GO:0005515 protein binding
CC TAS GO:0005576 extracellular region
CC IBA GO:0005615 extracellular space
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Gene expression in normal tissue: IFNA2

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

undefined24Proteasome1WNT signaling1DNA replication1Chromatin histone acetylation1p53 pathway1Chromatin other1

Pathways in IFNA2


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Database
Pathway ID
Pathway Des.
reactome R-HSA-109582 Hemostasis
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-1280215 Cytokine Signaling in Immune system
reactome R-HSA-168249 Innate Immune System
reactome R-HSA-168256 Immune System
reactome R-HSA-168256 Immune System
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Gene-Drug: Aster Plot


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Drug ID
Drug Name
Model Num.
iGMDRD263 AACOCF3 1
iGMDRD886 Compound 1541A 2
iGMDRD451 Serdemetan 1
iGMDRD268 Cerulenin 2
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Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in IFNA2

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Model
Level
Reference ID
Tissue
Cancer
Drug
Clinical Response
Source
No matching records found

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