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iGMDRD267

Canonical SMILES: CCC1CCC2C(C(C(C3(O2)CCC(C(O3)CC(C)O)C)C)OC(=O)C=CC(C(C(C(=O)C(C(C(C(=O)C(C(C(CC=CC=C1)C)O)(C)O)C)O)C)C)O)C)C

InChI: InChI=1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15+,21-18+/t25-,26-,27+,28+,29+,30-,31-,32-,33-,34-,35-,36-,38+,40+,41+,42-,44+,45-/m1/s1

InChI Key: MNULEGDCPYONBU-WMBHJXFZSA-N

Standard Name	CHEMBL	Pubchem CID	Drug Status	Drug Type
Oligomycin A	CHEMBL2007230	5281900	Alone	Small Molecule

Drug Targets:

ATP5L2

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
1105	CHD1	1
9833	MELK	2
8019	BRD3	3
5027	P2RX7	5
10641	NPRL2	2
23085	ERC1	1
6774	STAT3	1
7421	VDR	3
26191	PTPN22	2
11183	MAP4K5	2
8929	PHOX2B	3
2200	FBN1	3
57554	LRRC7	3
9149	DYRK1B	4
3757	KCNH2	4
8289	ARID1A	3
6351	CCL4	3
80070	ADAMTS20	7
8266	UBL4A	2
25778	DSTYK	3
353345	GPR141	4
843	CASP10	1
79820	CATSPERB	5
64783	RBM15	6
4771	NF2	3
3694	ITGB6	2
5218	CDK14	1
7253	TSHR	2
23310	NCAPD3	6
3195	TLX1	6
5298	PI4KB	1
3841	KPNA5	5
2241	FER	3
6318	SERPINB4	1
2249	FGF4	3
28231	SLCO4A1	3
1387	CREBBP	2
2043	EPHA4	2
8844	KSR1	3
5467	PPARD	1
23225	NUP210	3
2313	FLI1	2
4283	CXCL9	3
5579	PRKCB	3
31	ACACA	4
7133	TNFRSF1B	3
10178	TENM1	7
9699	RIMS2	2
9411	ARHGAP29	2
8295	TRRAP	5
10438	C1D	7
23617	TSSK2	2
5159	PDGFRB	1
51512	GTSE1	3
89910	UBE3B	3
974	CD79B	6
2033	EP300	3
6927	HNF1A	4
9578	CDC42BPB	2
23522	KAT6B	2
284521	OR2L13	3
440279	UNC13C	2
5607	MAP2K5	2
152137	CCDC50	5
256646	NUTM1	3
2268	FGR	2
8767	RIPK2	1
2051	EPHB6	2
222484	LNX2	2
6256	RXRA	1
26353	HSPB8	3
2242	FES	7
10342	TFG	3
22984	PDCD11	4
200576	PIKFYVE	2
8313	AXIN2	2
116986	AGAP2	4
51343	FZR1	3
23255	MTCL1	1
9636	ISG15	4
2736	GLI2	2
6928	HNF1B	8
83931	STK40	1
1992	SERPINB1	3
7016	TESK1	2
238	ALK	2
171019	ADAMTS19	3
375449	MAST4	3
22858	ICK	2
65217	PCDH15	8
55361	PI4K2A	6
23387	SIK3	2
6416	MAP2K4	1
9759	HDAC4	3
64170	CARD9	3
10087	COL4A3BP	1
2068	ERCC2	5
6098	ROS1	3
9472	AKAP6	3
2778	GNAS	3
3667	IRS1	3
2580	GAK	3
139285	AMER1	7
575	ADGRB1	3
53942	CNTN5	6
2734	GLG1	6
1123	CHN1	1
7010	TEK	4
7533	YWHAH	5
5450	POU2AF1	3
898	CCNE1	3
5327	PLAT	6
5863	RGL2	2
10290	SPEG	2
2201	FBN2	4
10062	NR1H3	3
27436	EML4	2
83694	RPS6KL1	1
861	RUNX1	1
27347	STK39	3
7157	TP53	2
6092	ROBO2	3
4602	MYB	3
3673	ITGA2	1
2322	FLT3	1
7869	SEMA3B	1
3791	KDR	1
10114	HIPK3	3
114788	CSMD3	2
54498	SMOX	1
84513	PLPP5	3
2133	EXT3	3
225689	MAPK15	2
1019	CDK4	8
84075	FSCB	3
9967	THRAP3	3
1045	CDX2	2
105	ADARB2	2
863	CBFA2T3	2
10516	FBLN5	5
7038	TG	2
65125	WNK1	3
136332	LRGUK	1
676	BRDT	2
5650	KLK7	2
5871	MAP4K2	3
80205	CHD9	2
10499	NCOA2	1
8997	KALRN	3
23469	PHF3	2
6654	SOS1	1
672	BRCA1	3
7204	TRIO	3
9252	RPS6KA5	3
23373	CRTC1	3
9448	MAP4K4	3
285220	EPHA6	4
546	ATRX	2
3417	IDH1	2
5606	MAP2K3	5
10926	DBF4	2
30827	CXXC1	3
5578	PRKCA	1
84823	LMNB2	3
5290	PIK3CA	11
5034	P4HB	3
8202	NCOA3	3
4293	MAP3K9	5
26524	LATS2	3
2318	FLNC	2
5530	PPP3CA	1
4803	NGF	2
7075	TIE1	1
744	MPPED2	4
1956	EGFR	3
4318	MMP9	3
4609	MYC	3
2624	GATA2	3
3308	HSPA4	3
5789	PTPRD	5
26278	SACS	6
894	CCND2	1
1440	CSF3	4
3635	INPP5D	1
8900	CCNA1	3
375056	MIA3	2
7189	TRAF6	1
23005	MAPKBP1	2
10186	LHFPL6	7
6872	TAF1	3
203102	ADAM32	2
57082	KNL1	1
1213	CLTC	4
3315	HSPB1	1
57538	ALPK3	2
8924	HERC2	2
6469	SHH	2
120892	LRRK2	2
65268	WNK2	2
2867	FFAR2	1
6095	RORA	3
29844	TFPT	3
7301	TYRO3	1
11184	MAP4K1	3
8626	TP63	1
1024	CDK8	3
7849	PAX8	4
4298	MLLT1	3
5979	RET	1
10253	SPRY2	2
9509	ADAMTS2	1
8621	CDK13	3
23396	PIP5K1C	2
23049	SMG1	4
5595	MAPK3	5
667	DST	2
23281	MTUS2	6
85409	NKD2	3
5896	RAG1	6
3678	ITGA5	4
7042	TGFB2	6
7273	TTN	6
1445	CSK	2
8522	GAS7	2
79834	PEAK1	2
5582	PRKCG	2
7059	THBS3	1
10257	ABCC4	2
85415	RHPN2	1
2277	VEGFD	4
54904	NSD3	4
53904	MYO3A	2
29941	PKN3	3
2046	EPHA8	3
282974	STK32C	3
5588	PRKCQ	4
2690	GHR	3
5395	PMS2	2
53353	LRP1B	1
7094	TLN1	2
1281	COL3A1	1
63976	PRDM16	2
7293	TNFRSF4	2
2049	EPHB3	1
283455	KSR2	3
3624	INHBA	3
598	BCL2L1	1
5587	PRKD1	7
5583	PRKCH	1
5589	PRKCSH	4
5170	PDPK1	1
2131	EXT1	3
2157	F8	3
79837	PIP4K2C	4
8428	STK24	3
4261	CIITA	3
7046	TGFBR1	4
2122	MECOM	1
51167	CYB5R4	1
1760	DMPK	1
9212	AURKB	6
4217	MAP3K5	3
1515	CTSV	1
2065	ERBB3	4
2074	ERCC6	3
10420	TESK2	1
7403	KDM6A	1
197259	MLKL	1
5586	PKN2	3
55959	SULF2	1
51135	IRAK4	2
142	PARP1	4
2073	ERCC5	3
4040	LRP6	3
4763	NF1	1
57697	FANCM	4
9625	AATK	1
494551	WEE2	3
1840	DTX1	1
4591	TRIM37	1
3679	ITGA7	3
1608	DGKG	3
3265	HRAS	3
83732	RIOK1	3
29110	TBK1	7
2444	FRK	1
3440	IFNA2	1
1436	CSF1R	1
4916	NTRK3	3
26206	SPAG8	5

Gene in drug-gene network: Network Plot

Models in Oligomycin A

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.