GO terms in PIP4K2C


Term TypeEvidence TypeGO Term IDGO Des.
BPTASGO:0006661phosphatidylinositol biosynthetic process
BPIMPGO:0010506regulation of autophagy
BPTASGO:0014066regulation of phosphatidylinositol 3-kinase signaling
BPIEAGO:0046854phosphatidylinositol phosphorylation
BPIMPGO:2000786positive regulation of autophagosome assembly
CCIMPGO:0005776autophagosome
CCTASGO:0005829cytosol
CCIEAGO:0016020membrane
CCHDAGO:0070062extracellular exosome
MFIEAGO:0005524ATP binding
MFEXPGO:00163091-phosphatidylinositol-5-phosphate 4-kinase activity
MFIPIGO:0042802identical protein binding

Gene expression in normal tissue: PIP4K2C

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PIP4K2C


DatabasePathway IDPathway Des.
reactomeR-HSA-1257604PIP3 activates AKT signaling
reactomeR-HSA-1430728Metabolism
reactomeR-HSA-1483255PI Metabolism
reactomeR-HSA-1483257Phospholipid metabolism
reactomeR-HSA-162582Signal Transduction
reactomeR-HSA-1660499Synthesis of PIPs at the plasma membrane
reactomeR-HSA-199418Negative regulation of the PI3K/AKT network
reactomeR-HSA-212436Generic Transcription Pathway
reactomeR-HSA-3700989Transcriptional Regulation by TP53
reactomeR-HSA-556833Metabolism of lipids
reactomeR-HSA-5633007Regulation of TP53 Activity
reactomeR-HSA-6804758Regulation of TP53 Activity through Acetylation
reactomeR-HSA-6811555PI5P Regulates TP53 Acetylation
reactomeR-HSA-6811558PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
reactomeR-HSA-73857RNA Polymerase II Transcription
reactomeR-HSA-74160Gene expression (Transcription)
reactomeR-HSA-8847453Synthesis of PIPs in the nucleus
reactomeR-HSA-9006925Intracellular signaling by second messengers
netpathPathway_BCRBCR
humancycPWY-6351D-myo-inositol (1,4,5)-trisphosphate biosynthesis
humancycPWY-6367D-myo-inositol-5-phosphate metabolism
humancycPWY-6371superpathway of inositol phosphate compounds
kegghsa00562Inositol phosphate metabolism - Homo sapiens (human)
kegghsa04070Phosphatidylinositol signaling system - Homo sapiens (human)
kegghsa04810Regulation of actin cytoskeleton - Homo sapiens (human)
wikipathwaysWP51Regulation of Actin Cytoskeleton

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD886Compound 1541A3
iGMDRD82Quiflapon2
iGMDRD414MST-3124
iGMDRD871BRD63684
iGMDRD286Nsc 6328396
iGMDRD872BRD71372
iGMDRD705Nakiterpiosin6
iGMDRD434BMS-5369241
iGMDRD213SMR0000686502
iGMDRD267Oligomycin A4
iGMDRD123Isoevodiamine1
iGMDRD237ABT-7511
iGMDRD523Cyanoquinoline, 114
iGMDRD148Pifithrin-mu2
iGMDRD60Quinoclamine3
iGMDRD23Gossypol5
iGMDRD188Piperlongumine4
iGMDRD100Zebularine2
iGMDRD887Compound 23 citrate2
iGMDRD74Idarubicin2
iGMDRD506Fedratinib2
iGMDRD888Compound 441
iGMDRD562Navitoclax4
iGMDRD782DC-45-A21
iGMDRD52Rotenone2
iGMDRD270Ciclosporin2
iGMDRD255SB2250022
iGMDRD280CYTOCHALASIN B3
iGMDRD446LY 21832402
iGMDRD201SKI II2
iGMDRD316N9-Isopropyl-olomoucine2
iGMDRD546BMS-7548073
iGMDRD427ABT7375
iGMDRD144NSC953972
iGMDRD781Sirolimus4
iGMDRD484Pluripotin4
iGMDRD126Tipifarnib4
iGMDRD889Compound 7d-cis4
iGMDRD772BRD47702
iGMDRD579PF7502

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PIP4K2C

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