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iGMDRD705

Canonical SMILES: CC1CC(OC1=O)C(C(C2=C(C3=C(C=C2)C4CC(C56C(OCC(O5)CC6(C4C3=O)C)O)Br)C)C(Cl)Cl)O

InChI: InChI=1S/C27H31BrCl2O7/c1-10-6-16(36-24(10)33)21(31)19(23(29)30)13-4-5-14-15-7-17(28)27-25(34)35-9-12(37-27)8-26(27,3)20(15)22(32)18(14)11(13)2/h4-5,10,12,15-17,19-21,23,25,31,34H,6-9H2,1-3H3/t10-,12+,15-,16+,17+,19-,20+,21+,25+,26?,27+/m0/s1

InChI Key: ZZCVHHDIBFSYFY-JMQRXBQWSA-N

Standard Name	Pubchem CID	Drug Status	Drug Type
Nakiterpiosin	54613400	Alone	Small Molecule

Drug-model tissue-cancer distribution: Bubble Plot

Drug-gene pathway enrichments

Drug-gene GO enrichments

Drug-Gene: Aster Plot

Gene ID	Gene Name	Model Num.
1105	CHD1	2
27125	AFF4	4
5296	PIK3R2	3
5027	P2RX7	2
10903	MTMR11	3
79054	TRPM8	3
10641	NPRL2	3
23085	ERC1	4
7128	TNFAIP3	3
21	ABCA3	1
6581	SLC22A3	3
8915	BCL10	2
8476	CDC42BPA	3
7750	ZMYM2	4
4926	NUMA1	1
11183	MAP4K5	8
4627	MYH9	3
23513	SCRIB	3
2956	MSH6	4
2200	FBN1	3
57679	ALS2	2
9706	ULK2	3
7272	TTK	2
347365	ITIH6	7
3845	KRAS	1
3757	KCNH2	2
6563	SLC14A1	3
8289	ARID1A	2
80070	ADAMTS20	1
5934	RBL2	3
25778	DSTYK	3
3431	SP110	3
2475	MTOR	6
6597	SMARCA4	4
4036	LRP2	6
7764	ZNF217	3
11160	ERLIN2	2
5241	PGR	3
353345	GPR141	2
5133	PDCD1	1
843	CASP10	3
3069	HDLBP	3
11116	FGFR1OP	4
10320	IKZF1	3
9530	BAG4	1
390502	SERPINA2	2
64783	RBM15	5
4771	NF2	2
23213	SULF1	5
1272	CNTN1	4
3066	HDAC2	3
23310	NCAPD3	5
8749	ADAM18	3
2241	FER	2
22821	RASA3	5
6318	SERPINB4	2
604	BCL6	3
51199	NIN	4
577	ADGRB3	2
28231	SLCO4A1	2
114783	LMTK3	3
5467	PPARD	2
23225	NUP210	5
2313	FLI1	3
4283	CXCL9	2
31	ACACA	3
10178	TENM1	3
79858	NEK11	2
8295	TRRAP	3
2977	GUCY1A2	2
10438	C1D	9
6722	SRF	3
5396	PRRX1	3
5159	PDGFRB	1
7373	COL14A1	6
7173	TPO	2
10215	OLIG2	3
4851	NOTCH1	2
89910	UBE3B	2
10295	BCKDK	2
2033	EP300	3
6927	HNF1A	2
64324	NSD1	3
83439	TCF7L1	4
25865	PRKD2	3
25925	ZNF521	9
7852	CXCR4	3
54477	PLEKHA5	4
57670	KIAA1549	2
22861	NLRP1	3
440279	UNC13C	2
4301	AFDN	2
342667	STAC2	3
1540	CYLD	3
8600	TNFSF11	3
7025	NR2F1	3
23012	STK38L	4
4478	MSN	3
222484	LNX2	6
6256	RXRA	3
329	BIRC2	5
9175	MAP3K13	1
5468	PPARG	2
8313	AXIN2	2
6091	ROBO1	5
2042	EPHA3	7
1050	CEBPA	5
2260	FGFR1	6
199699	DAND5	3
5330	PLCB2	3
730249	ACOD1	3
2736	GLI2	1
83990	BRIP1	2
4194	MDM4	3
23405	DICER1	2
238	ALK	2
399979	SNX19	1
65266	WNK4	4
65217	PCDH15	6
26750	RPS6KC1	3
79971	WLS	1
54899	PXK	3
286826	LIN9	6
7486	WRN	2
23191	CYFIP1	3
6709	SPTAN1	4
6793	STK10	4
2068	ERCC2	1
80312	TET1	2
9472	AKAP6	2
2778	GNAS	6
3685	ITGAV	2
3667	IRS1	2
80243	PREX2	2
472	ATM	3
139285	AMER1	5
8148	TAF15	3
53942	CNTN5	1
5924	RASGRF2	3
2734	GLG1	2
9564	BCAR1	2
1496	CTNNA2	2
7010	TEK	3
898	CCNE1	5
2066	ERBB4	2
5863	RGL2	2
10413	YAP1	6
2201	FBN2	2
1029	CDKN2A	1
5108	PCM1	3
9874	TLK1	3
11143	KAT7	3
11197	WIF1	3
8743	TNFSF10	2
5834	PYGB	1
58508	KMT2C	6
7157	TP53	1
27086	FOXP1	3
6714	SRC	6
4296	MAP3K11	2
2322	FLT3	2
4857	NOVA1	2
25836	NIPBL	2
8218	CLTCL1	2
147746	HIPK4	1
4292	MLH1	1
114788	CSMD3	2
2263	FGFR2	3
4086	SMAD1	1
5585	PKN1	1
1019	CDK4	3
11213	IRAK3	2
863	CBFA2T3	3
8874	ARHGEF7	2
1102	RCBTB2	2
23043	TNIK	2
4921	DDR2	3
55589	BMP2K	3
65125	WNK1	7
136332	LRGUK	4
4436	MSH2	2
676	BRDT	4
7175	TPR	6
5871	MAP4K2	6
80205	CHD9	3
4026	LPP	2
8997	KALRN	3
6795	AURKC	9
57551	TAOK1	6
23469	PHF3	3
4089	SMAD4	4
7204	TRIO	3
10733	PLK4	3
835	CASP2	3
546	ATRX	1
51366	UBR5	3
3426	CFI	2
23678	SGK3	6
7786	MAP3K12	3
10769	PLK2	6
56997	COQ8A	3
4214	MAP3K1	2
3702	ITK	4
440275	EIF2AK4	1
9972	NUP153	2
3239	HOXD13	3
5290	PIK3CA	2
92335	STRADA	2
5770	PTPN1	6
26524	LATS2	3
2318	FLNC	3
10565	ARFGEF1	2
675	BRCA2	8
607	BCL9	3
8445	DYRK2	1
157680	VPS13B	4
2735	GLI1	3
4609	MYC	8
11064	CNTRL	2
8021	NUP214	3
8013	NR4A3	3
51321	AMZ2	4
7297	TYK2	3
26278	SACS	1
29951	PDZRN4	4
51265	CDKL3	3
51701	NLK	2
5747	PTK2	3
3635	INPP5D	3
5187	PER1	4
7917	BAG6	3
375056	MIA3	3
10000	AKT3	3
93627	TBCK	4
137872	ADHFE1	9
7015	TERT	3
10186	LHFPL6	1
203102	ADAM32	2
673	BRAF	1
57082	KNL1	5
1981	EIF4G1	2
1213	CLTC	3
6011	GRK1	3
1769	DNAH8	4
23532	PRAME	3
4863	NPAT	2
780	DDR1	3
339345	NANOS2	2
89795	NAV3	4
2867	FFAR2	5
57507	ZNF608	3
7301	TYRO3	3
93273	LEMD1	4
7468	NSD2	3
8626	TP63	3
7849	PAX8	3
9321	TRIP11	2
9451	EIF2AK3	3
1977	EIF4E	4
4853	NOTCH2	2
23396	PIP5K1C	2
10752	CHL1	3
5728	PTEN	3
51592	TRIM33	2
8888	MCM3AP	5
667	DST	3
23281	MTUS2	5
115701	ALPK2	8
4004	LMO1	3
284086	NEK8	1
5347	PLK1	3
6770	STAR	2
2188	FANCF	3
2324	FLT4	3
177	AGER	1
2870	GRK6	3
8301	PICALM	3
7273	TTN	3
8522	GAS7	2
79834	PEAK1	3
23389	MED13L	7
6787	NEK4	6
55561	CDC42BPG	3
128869	PIGU	2
286151	FBXO43	2
57820	CCNB1IP1	3
344905	ATP13A5	3
10076	PTPRU	2
7248	TSC1	2
4619	MYH1	3
10111	RAD50	1
53353	LRP1B	2
9659	PDE4DIP	2
5335	PLCG1	3
5927	KDM5A	5
5587	PRKD1	6
10734	STAG3	3
2321	FLT1	1
6196	RPS6KA2	2
57448	BIRC6	3
2131	EXT1	3
3717	JAK2	8
22982	DIP2C	2
2157	F8	2
7227	TRPS1	3
5506	PPP1R3A	1
79837	PIP4K2C	6
3709	ITPR2	2
6778	STAT6	2
4067	LYN	2
1030	CDKN2B	1
65267	WNK3	4
6777	STAT5B	1
5932	RBBP8	2
3977	LIFR	3
3656	IRAK2	3
182	JAG1	6
7913	DEK	3
8536	CAMK1	3
2122	MECOM	9
5087	PBX1	3
3815	KIT	3
5925	RB1	3
4217	MAP3K5	3
1515	CTSV	3
4893	NRAS	2
2308	FOXO1	2
1432	MAPK14	6
112268437	LOC112268437	3
4638	MYLK	2
255239	ANKK1	3
4205	MEF2A	3
7040	TGFB1	6
3488	IGFBP5	5
3480	IGF1R	3
23092	ARHGAP26	3
10494	STK25	3
11086	ADAM29	3
142	PARP1	3
2261	FGFR3	4
23072	HECW1	2
55422	ZNF331	3
1013	CDH15	3
3092	HIP1	2
4763	NF1	2
63893	UBE2O	2
1840	DTX1	2
4591	TRIM37	3
57096	RPGRIP1	3
94	ACVRL1	1
2044	EPHA5	3
10048	RANBP9	6
7294	TXK	1
27255	CNTN6	2
1803	DPP4	1
83732	RIOK1	3
654790	PCP4L1	3
1499	CTNNB1	3
2444	FRK	5
56155	TEX14	3
2892	GRIA3	6
4916	NTRK3	3
1795	DOCK3	3
4486	MST1R	3

Gene in drug-gene network: Network Plot

Models in Nakiterpiosin

SITE

DATATYPES

CLASSFICATION

Disclaimer: iGMDR is intended for research purposes only. Its information cannot be used for emergencies or medical or professional advice.