LHFPL6
Summary: This gene is a member of the lipoma HMGIC fusion partner (LHFP) gene family, which is a subset of the superfamily of tetraspan transmembrane protein encoding genes. This gene is fused to a high-mobility group gene in a translocation-associated lipoma. Mutations in another LHFP-like gene result in deafness in humans and mice. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq, Jul 2008].
| Name | OMIM ID | Ensembl ID | HGNC ID | PHARMGKB ID | Map Location |
|---|---|---|---|---|---|
| LHFPL tetraspan subfamily member 6 | MIM:606710 | Ensembl:ENSG00000183722 | HGNC:HGNC:6586 | PA30358 | 13q13.3-q14.11 |
GO terms in LHFPL6
| Term Type | Evidence Type | GO Term ID | GO Des. |
|---|---|---|---|
| CC | IEA | GO:0016021 | integral component of membrane |
Gene expression in normal tissue: LHFPL6
Gene-model tissue-cancer distribution: Bubble Plot
Gene-drug pathway distribution
Pathways in LHFPL6
| Database | Pathway ID | Pathway Des. |
|---|
Gene-Drug: Aster Plot
| Drug ID | Drug Name | Model Num. |
|---|---|---|
| iGMDRD523 | Cyanoquinoline, 11 | 2 |
| iGMDRD424 | Tamatinib | 2 |
| iGMDRD532 | Olaparib | 2 |
| iGMDRD579 | PF750 | 3 |
| iGMDRD512 | nutlin 3 | 2 |
| iGMDRD126 | Tipifarnib | 1 |
| iGMDRD280 | CYTOCHALASIN B | 1 |
| iGMDRD901 | ELCPK | 2 |
| iGMDRD639 | YK 4-279 | 3 |
| iGMDRD446 | LY 2183240 | 1 |
| iGMDRD267 | Oligomycin A | 7 |
| iGMDRD441 | TW 37 | 3 |
| iGMDRD705 | Nakiterpiosin | 1 |
| iGMDRD6 | AM-580 | 5 |
| iGMDRD158 | NSC141540 | 2 |
| iGMDRD137 | Indisulam | 1 |
| iGMDRD444 | Tivantinib | 1 |
| iGMDRD23 | Gossypol | 1 |
| iGMDRD60 | Quinoclamine | 2 |
| iGMDRD886 | Compound 1541A | 1 |
| iGMDRD300 | Tozasertib | 1 |
| iGMDRD888 | Compound 44 | 1 |
| iGMDRD506 | Fedratinib | 1 |
| iGMDRD730 | Kahalalide F | 2 |
| iGMDRD74 | Idarubicin | 2 |
| iGMDRD872 | BRD7137 | 8 |
| iGMDRD871 | BRD6368 | 1 |
| iGMDRD367 | Ro 28-1675 | 5 |
| iGMDRD286 | Nsc 632839 | 7 |
Gene in drug-gene network: Network Plot
Gene-drug targets distribution
Gene Structure: PDB
Models in LHFPL6
CLASSFICATION
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