PDE4DIP


Summary: The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

NameOMIM IDEnsembl IDHGNC IDPHARMGKB IDMap Location
phosphodiesterase 4D interacting proteinMIM:608117Ensembl:ENSG00000178104HGNC:HGNC:15580PA331311q21.2

GO terms in PDE4DIP


Term TypeEvidence TypeGO Term IDGO Des.
CCIDAGO:0005634nucleus
CCIDAGO:0005737cytoplasm
CCIDAGO:0005794Golgi apparatus
CCISSGO:0005794Golgi apparatus
CCIDAGO:0005813centrosome
CCISSGO:0005813centrosome
CCISSGO:0030016myofibril
BPISSGO:0034622cellular protein-containing complex assembly
BPIDAGO:1903358regulation of Golgi organization
MFIPIGO:0005515protein binding
MFISSGO:0019899enzyme binding
MFIDAGO:0032947protein-containing complex scaffold activity

Gene expression in normal tissue: PDE4DIP

Gene-model tissue-cancer distribution: Bubble Plot

Gene-drug pathway distribution

Pathways in PDE4DIP


DatabasePathway IDPathway Des.

Gene-Drug: Aster Plot


Drug IDDrug NameModel Num.
iGMDRD871BRD63681
iGMDRD286Nsc 6328398
iGMDRD329Merck608
iGMDRD662JQ-13
iGMDRD552AZD-17754
iGMDRD103SN-386
iGMDRD137Indisulam4
iGMDRD158NSC1415402
iGMDRD5Tyrphostin AG 14782
iGMDRD105Triptolide5
iGMDRD705Nakiterpiosin2
iGMDRD341Triacsin c3
iGMDRD237ABT-7512
iGMDRD123Isoevodiamine3
iGMDRD150RITA3
iGMDRD523Cyanoquinoline, 111
iGMDRD79Gemcitabine1
iGMDRD188Piperlongumine2
iGMDRD399Selumetinib1
iGMDRD74Idarubicin2
iGMDRD64Parbendazole6
iGMDRD356PNU-746543
iGMDRD524ISX-92
iGMDRD260FQI-26
iGMDRD294Batimastat1
iGMDRD639YK 4-2791
iGMDRD61Kinetin riboside3
iGMDRD2PK-111953
iGMDRD679Bistramide A1
iGMDRD466Chaetocin2
iGMDRD76Simvastatin3
iGMDRD126Tipifarnib2
iGMDRD433Lexibulin5
iGMDRD151CHM-16
iGMDRD889Compound 7d-cis1
iGMDRD420Leucascandrolide A5
iGMDRD427ABT7372
iGMDRD670ML 2103
iGMDRD779PRL-3 Inhibitor I3
iGMDRD484Pluripotin3
iGMDRD781Sirolimus2
iGMDRD872BRD71373
iGMDRD300Tozasertib2
iGMDRD505Pevonedistat3
iGMDRD246NPC263
iGMDRD42Vorinostat3
iGMDRD192CIL562
iGMDRD231Importazole3
iGMDRD85Ursolic acid2
iGMDRD351GW843682X2
iGMDRD512nutlin 35
iGMDRD116CD4373
iGMDRD345Compound 10b [PMID: 11504634]6
iGMDRD100Zebularine2
iGMDRD887Compound 23 citrate3
iGMDRD398Sepantronium2
iGMDRD562Navitoclax8
iGMDRD60Quinoclamine5
iGMDRD480KU00606484
iGMDRD138PX 126
iGMDRD255SB2250022
iGMDRD318PAC-11
iGMDRD446LY 21832403
iGMDRD193Fqi15
iGMDRD280CYTOCHALASIN B4
iGMDRD634SCHEMBL26080413
iGMDRD387CHIR-990212
iGMDRD1008SR-II-138A3
iGMDRD144NSC953973
iGMDRD494Neopeltolide3

Gene in drug-gene network: Network Plot

Gene-drug targets distribution

Gene Structure: PDB

Models in PDE4DIP

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